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Membership type: full

Lebo Francina Gafane-Matemane

Country of origin: South Africa Currently in: South Africa, Potchefstroom General field of specialization: Medical and Health Sciences incl Neurosciences
Academic Background

Degrees

2017 Doctorate Medical and Health Sciences incl Neurosciences
2014 Master Medical and Health Sciences incl Neurosciences
2011 Undergraduate Medical and Health Sciences incl Neurosciences
2010 Undergraduate Structural, Cell and Molecular Biology
Research and Profession

Current Research Activities

Medical and Health Sciences incl Neurosciences

Her research focuses on the low renin phenotype, particularly in Africans. This phenotype is characterised by volume-loading hypertension and salt sensitivity. She is interested in the role of the renin-angiotensin-aldosterone system, salt intake and sympathetic activity in the development of hypertension. Additionally, she is also collaborating with other researchers in creating awareness in the communities regarding hypertension and its co-morbidities.

Research Keywords: 
Hypertension
renin-angiotensin-aldosterone system
cardiovascular diseases

Publications resulting from Research: 


1. Crouch SH, Ware LJ, Gafane-Matemane LF, Kruger HS, Van Zyl T, Van der Westhuizen B, Schutte AE. Dietary sodium intake and its relationship to adiposity in young black and white adults: The African-PREDICT study. J Clin Hypertens 2018 Accepted May.
2. Breet Y, Huisman HW, Kruger R, van Rooyen JM, Gafane-Matemane LF, Ware LJ, Schutte AE. Pulse pressure amplification and its relationship with age in young, apparently healthy black and white adults: The African-PREDICT study. Int J Cardiol. 2017; 249: 387-391 doi: 10.1016/j.ijcard.2017.08.070. (IF=6.189)
3. Schutte AE, Botha S , Fourie CMT, Gafane-Matemane LF, Kruger R, Lammertyn L, Malan L, Mels CMC, Schutte R, Smith W, van Rooyen JM, Ware LJ,Huisman HW. Recent advances in understanding hypertension development in sub-Saharan Africa. J Hum Hypertens, 2017; 31(8):491-500. (IF=2.700)
4. Van Rooyen JM, Poglitsch M, Huisman HW, Mels CMC, Kruger R, Malan L, Botha S, Lammertyn L, Gafane L, Schutte AE. Quantification of systemic renin-angiotensin system peptides of hypertensive black and white African men established from the RAS-Fingerprint. J Renin-Angio-Aldo S (JRAAS), 2016; 17(4): 1-7. (IF=2.350)
5. Ware LJ, Rennie KL, Gafane LF, Nell TM, Thompson JES, Van Rooyen JM, Schutte R, Schutte AE. Masked hypertension in low-income South African adults. J Clin Hypertens (Greenwich), 2016; 18(5): 396-404. (IF=2.851)
6. Gafane LF, Schutte R, Van Rooyen JM, Schutte AE. Plasma renin and cardiovascular responses to the cold pressor test differ in black and white populations: The SABPA study J Hum Hypertens, 2016; 30(5): 346-51. (IF=2.700).
7. Gafane LF, Schutte R, Kruger IM, Schutte AE. Large artery stiffness and carotid intima-media thickness in relation to markers of calcium and bone mineral metabolism in African women older than 46 years: the PURE study The PURE-study. J Hum Hypertens, 2015; 29(3): 152-158. (IF=2.692)
8. Gafane L, Schutte A, Van Rooyen J, Schutte R. OS 32-08 Sympathetic nerve activity and the low renin phenotype: the SABPA study. International Society of Hypertension Meeting 2016 Seoul. Abstract published in: J Hypertens, 2016; 34 Suppl 1:e391.
9. CM Fourie, JM van Rooyen, HW Huisman, CM Mels, W Smith, R Kruger, S Botha, L Lammertyn, L Gafane, AE Schutte. Arterial stiffness in a black South African cohort infected with the human immunodeficiency virus (HIV). European Atherosclerosis Society Congress 2016 Innsbruck. Abstract published in: Atherosclerosis 252, e150.
10. Schutte, A., Gafane, L., Kruger, I. and Schutte, R. Large artery stiffness and carotid intima-media thickness in relation to markers of bone mineral metabolism in postmenopausal African women: The PURE-study. World Congress of Cardiology, Melbourne, Australia, 4-7 May 2014. Abstract published in: Global Heart 1 (9), e211.



Current profession

Current professional activities type: 
Research
Teaching
Teaching: Senior Lecturer in Human Physiology for undergraduate students in the Faculty of Health Sciences. Research: Involved in several research projects on cardiovascular diseases in terms of data collection and analyses, training of postgraduate students, article writing and hypertension awareness activities.

Workshop and Conference Attended

2014 North-West University, Potchefstroom, South Africa HIV counselling and testing, USAID & Foundation for Professional Development
2017 North-West University, Potchefstroom, South Africa International Research Grant Proposal Writing Workshop
2018 North-West University, Potchefstroom, South Africa NWU Health Research Ethics Training Course
2018 North-West University, Potchefstroom, South Africa Design thinking workshop for Health Professions
2016 North-West University, Potchefstroom, South Africa Records Management Workshop

Affiliations

Physiology Society of Southern Africa
Southern Africa Hypertension Society
International Society of Hypertension

Presentation given

2017
The low renin phenotype in Africans: Implications for all-cause and cardiovascular mortality.
Johannesburg, South Africa
Event: Society of Endocrinology, Metabolism, and Diabetes for South Africa (SEMDSA) Congress
2016
Sympathetic nerve activity and the low renin phenotype: the SABPA study.
Seoul, South Korea
Event: International Society of Hypertension Meeting 2016
2016
Renin predicts all-cause and cardiovascular mortality in Africans with low renin levels.
Muldersdrift, South Africa
Event: Stroke and Hypertension Congress
2014
Large artery stiffness and carotid intima-media thickness in relation to markers of bone mineral metabolism in African women older than 46 years: The PURE-study
Durban, South Africa
Event: Stroke and Hypertension Congress
2015
Plasma renin and cardiovascular responses to the cold pressor test differ in black and white populations
Parys, Free state, South Africa
Event: The Physiology Society of Southern Africa Congress
Prizes, Grants and Awards

Other Awards

Jun 2011
Industrial Development Corporation (IDC) award for Best Student in Physiology
Award given to the best student in undergraduate Physiology
Aug 2016
Platinum Award for Best Oral presentation
Platinum Award for Best Oral presentation at the Stroke and Hypertension Congress
Sep 2016
International Society of Hypertension Scientific Meeting Travel Grant
International Society of Hypertension Scientific Meeting Travel Grant to attend the scientific meeting in Seoul

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