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Membership type: full

Mylene Uy Uy

Country of origin: Philippines Currently in: Philippines, Iligan City General field of specialization: Chemical Sciences
Academic Background

Degrees

2005 Doctorate Chemical Sciences
Research and Profession

Current Research Activities



Working on the discovery and development of natural products from terrestrial and marine resources as drug leads or herbal supplements for infectious diseases, cancer and oxidative stress-related diseases

Research Keywords: 
Drug discovery
MEDICINAL PLANTS
marine organisms
herbal products
Anticancer agents

Publications resulting from Research: 


1. Evaluation of the antioxidant and antimicrobial potentials of marine invertebrates collected off Agusan del Norte, Philippines: Lobophytum baratum, Sarcophyton ehrenbergi, Isis sp., and Demospongia sp.
M.K.P. Barela, E. B. Metillo, M. M. Uy
International Journal of Biosciences, 12(4): 127-133, 2018.
2. Ficusnotins A-F: Rare diarylbutanoids from the leaves of Ficus nota
F. S. Latayada, M. M. Uy, Y. Akihara, E. Ohta, T. Nehira, H. Omura, S. Ohta
Phytochemistry ,141:98-104, 2017.
3. Two New C11-Terpenes with an Octahydrobenzofuran Skeleton Isolated from the Leaves of Ficus nota
F. S. Latayada, M. M. Uy, Y. Akihara, E. Ohta, S. Ohta
Phytochemistry Letters, 19:237–240, 2017.
4. Phytochemical analysis and cytotoxic activity of ant plant (Myrmecodia tuberosa Jack.)
M. T. Demetillo, M. L. Baguio, M. M. Uy and Olga M. Nuñeza
Journal of Biodiversity and Environmental Sciences, 11(6):85-91, 2017.
5. Ethnobotany of Medicinal Plants Used by the Talaandig Tribe in Brgy. Lilingayon, Valencia, Bukidnon, Philippines
N. M. 0. Odchimar, O. M. Nuñeza, M. M. Uy, W. T. P. S. K. Senarath
Asian Journal of Biological and Life Sciences, 6:358-364, 2017.
Cytotoxicity and Photochemical Screening of Four Species of Plants from Pualas, Lanao del Sur, Philippines
Asian Journal of Biological and Life Sciences, 6:394-398, 2017.
6. Toxicity and Antioxidant Potential Screening of Extracts from Five Marine Sponges Collected off Zamboanga Peninsula, Philippines
J. M. Francisco, M. M. Uy
Asian J. of Biological and Life Sciences, 5(3):233-236, 2016.
7. Antimicrobial Activities and Toxicities of the Leaf Extracts of Ficus nota (Blanco) Merr
F. S. Latayada, M. M. Uy
Accepted for Publication, Asian J. of Biological and Life Sciences, 5(3):248-252, 2016.
6. Toxicity and Hypoglycemic Effect of Tannin-Containing Extract from the Mangrove Tree Sonneratia Alba Sm.
N.J. Morada, EB Metillo, M. M. Uy, J. M. Oclarit
Bull. Env. Pharmacol. Life Sci., Vol 5(6):58-64, 2016.
8. Antioxidant Activity, Total Phenolic Content, and GC-MS Analysis of the root of Kawilan (Embelia philippinensis A. DC.)
N. M. O. Odchimar, O, M. Nuñeza, M. M. Uy, W. T. P. S. K. Senarath
Bull. Env.Pharmacol. Life Sci., Vol 5(5): 42-47, 2016.
9. Ethnobotany of Medicinal Plants Used by the Subanen of Lapuyan, Zamboanga del Sur
J. R. L. Pizon, O. M. Nuñeza, M. M. Uy, W. T. P. S. K. Senarath
Bull. Env.Pharmacol. Life Sci., Vol 5(5): 53-67, 2016.
10. Cytotoxicity to Artemia salina L. of Marine Sponge Extracts from Surigao del Norte, Philippines
C. D. Gelani, M. M. Uy
Bull.Environment, Pharmacology and Life Sciences 5(5):14-18, 2016.
11. Screening of the Antioxidant Properties of the Leaf Extracts of Philippine Medicinal Plants Ficus nota (Blanco) Merr., Metroxylon sagu Rottb., Mussaenda philippica A. Rich., Inocarpus fagifer, and Cinnamomum mercadoi Vidal
F. S. Latayada, M. M. Uy
Bulletin of Environment, Pharmacology and Life Sciences 5(3):18-24, 2016.
12. Bioactivity studies on the extracts and the phlebotonic diosmetin isolated from Premna odorata Blanco (Lamiaceae)
L. Pinzon, M. Uy
Bulletin of Environment, Pharmacology and Life Sciences 5(3): 1-4, 2016.
13. In vitro alpha-amylase and antioxidant activities of bark extracts of charcoal tree (Trema orientalis Linn.)
D. J. V. L. Trono, O. M. Nuñeza, M. M. Uy and W. T. P. S. K. Senarath
International Journal of Biosciences 8(1): 33-46, 2016.
14. GC-MS Analysis and evaluation of in vitro antioxidant potential and total phenolics content of wild hops (Flemingia strobilifera (l.) W. T. Aiton)
J. R. L Pizon, O. M. Nuñeza, M. M. Uy and W. T. P. S. K. Senarath
International Journal of Biosciences 8(1): 25-32, 2016.
15. Brine Shrimp Lethality Assay of the Ethanol Extracts of Antidesma ghaesembilla Gaerth
R.P. Jose, K. P. Ramos, M. L. Gelsao, O. M. Nuñeza and M. M. Uy
Bulletin of Environment, Pharmacology and Life Sciences 4(9): 88-92, 2015.
16. Evaluating the Potential Cytotoxic Activity of Ficus nota Using Brine Shrimp Lethality Test
C. D. Arquion, O. M. Nuñeza and M. M. Uy
Bulletin of Environment, Pharmacology and Life Sciences 4(12): 40-44, 2015.
17. Toxicity and antioxidant properties of the extracts of Prunus grisea (C. Muell.) Kalkm leaves
M. M. Uy and P. T. Pundogar
Asian Journal of Biological and Life Sciences, 4(2):81-86, 2015.
18. The brine shrimp lethality of the leaf extracts of Piper baccatum Blume and their antioxidant properties
M. M. Uy and M. P. Villanueva
Asian Journal of Biological and Life Sciences, 4(3):179-184, 2015.
19. The antioxidant properties of the Philippine medicinal plants Cassia sophera Linn., Derris elliptica Benth, Ficus minahassea Tesym. and De Vr., Leea aculeata Blume and Leucosyke capitellata Wedd.
M. M. Uy and M. G. L. Villazorda
AAB Bioflux 7(3):150-156, 2015.
20. Brine shrimp lethality assay of whole plant extracts of Eleusine indica
M. A. Responte,M. R. B. Dacar, O.M. Nuñeza and M. M. Uy
AAB Bioflux 7(2):90-95, 2015.
21. Evaluation of toxicity and antioxidant activities of the crude leaf extracts of
Cnidoscolus chayamansa
J.B. Espinosa and M. M. Uy
AAB Bioflux 7(2):109-114, 2015.
22. Evaluation of the antioxidant properties of the leaf extracts of Philippine medicinal
plants Casuarina equisetifolia Linn, Cyperus brevifolius (Rottb) Hassk, Drymoglossum piloselloides Linn, Ixora chinensis Lam, and Piper abbreviatum Opiz.
M. M. Uy and K. I. Garcia
AAB Bioflux 7(2):71-79, 2015.
23. Evaluation of the phytochemical constituents of the leaves of Ficus minahassae Tesym & De Vr., Casuarina equisetifolia Linn., Leucosyke capitellata (Pior) Wedd., Cassia sophera Linn., Derris elliptica Benth., Cyperus brevifolius (Rottb.) Hassk., Piper abbreviatum Opiz., Ixora chinensis Lam.,
Leea aculeata Blume, and Drymoglossum piloselloides Linn.
R.A.E. Lagunay and M. M. Uy
ABB Bioflux 7(1):51-58, 2015.
24. Brine Shrimp Lethality Test of Kleinhovia hospita stem and bark from Agusan del Sur, Philippines
L.J.G. Morilla, O.M. Nuñeza and M.M. Uy
ELBA Bioflux 7(1):61-66, 2015.
25. Effect of Phyllanthus niruri and Passiflora foetida Extracts on the Mortality and Survival rate of the Brine Shrimp Artemia salina
J. Juzavil, E. Mondejar, O. Nuñeza and M. Uy
Research Journal of Recent Sciences 4(2):61-67, 2015.
26. Evaluating the Potential Cytotoxic Activity of Acmella grandifolia Flower and Whole Plant Using Bring Shrimp Lethality Test
N.U. Elias, O.M. Nuῆeza and M.M. Uy
International Journal of Biological Sciences 3(10): 90-92, 2014.
27. Brine Shrimp (Artemia salina) Bioassay of the Medicinal Plant Pseudelephantopus spicatus from Iligan City, Philippines
J.A. Lalisan, O.M. Nuῆeza and M.M. Uy
International Research Journal of Biological Sciences 3(9):47-50, 2014.
28. In vitro Antioxidant and Cytotoxic Activities of Some Marine Sponges Collected Off
Misamis Oriental Coast, Philippines
A.P. Rivera and M. M. Uy
E-Journal of Chemistry 9(1):354-358, 2012.
29. Isolation and characterization of antimicrobial, anti-inflammatory and chemopreventive flavones from Premna odorata Blanco
L.C. Pinzon, M. M. Uy, K. H. Sze, M. Wang and I.K. Chu
J. of Med. Plant Res. 5(13):2729-2735, 2011.


30. Antioxidant and Cytotoxic Activities and Phytochemical Screening of Four Philippine
Medicinal Plants
N.P. Peteros and M.M. Uy
J. of Med. Plant Res. 4(5):407-414, 2010.
31. Antioxidant Hyrdoxycinammic Acid Derivatives Isolated from Brazilian Bee Pollen
S. Ohta, T. Fujitaki, M. M. Uy, M. Yanai, A. Yukiyoshi and T. Hirata
Nat. Prod. Res, 21(8):726-732, 2007.
32. Exiguolide, A New Macrolide from the Marine Sponge Geodia exigua
S. Ohta, M. M. Uy, M. Yanai, E. Ohta, T. Hirata and S. Ikegami
Tetrahedron Lett., 47(12):1957-1960, 2006.
33. New spirocyclic sesquiterpenes from the marine sponge Geodia exigua
M. M. Uy, S. Ohta, M. Yanai, E. Ohta, T. Hirata and S. Ikegami
Tetrahedron 59(6):731-736, 2003.
34. Exiguamide, a New Spirocyclic Sesquiterpene from the Marine sponge Geodia exigua
that Inhibits Cell Fate Specification During Sea Urchin Embryogenesis
M. M. Uy, S. Ohta, M. Yanai, E. Ohta, T. Hirata and S. Ikegami
Bioorg. Med. Chem. Lett. 12(21):3037-3039, 2002.



Current profession

Current professional activities type: 
Other
Currently Director of the Premier Research Institute of Science and Mathematics of our University; also teaching graduate courses and doing research

Prizes, Grants and Awards

Other Awards

Jul 2016
Novartis Next Generation Scientist