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Membership type: full

Soledad Astrada

Country of origin: Uruguay Currently in: Uruguay, Montevideo General field of specialization: Structural, Cell and Molecular Biology
Academic Background

Degrees

2011 Master Structural, Cell and Molecular Biology
Research and Profession

Current Research Activities

Structural, Cell and Molecular Biology

PhD Studen

Research Keywords: 
Cancer
Bioactive peptides
cellular biology

Publications resulting from Research: 


HT-29 and Caco-2 reporter cell lines for functional studies of nuclear factor kappa B activation. Mastropietro G, Tiscornia I, Perelmuter K, Astrada S, Bollati-Fogolín M.
Mediators Inflamm. 2015;2015:860534. doi: 10.1155/2015/860534. Epub 2015 Mar 10.
PMID: 25861164

Antitumor efficacy, pharmacokinetic and biodistribution studies of the anticancer peptide CIGB-552 in mouse models. Vallespí MG, Pimentel G, Cabrales-Rico A, Garza J, Oliva B, Mendoza O, Gomez Y, Basaco T, Sánchez I, Calderón C, Rodriguez JC, Markelova MR, Fichtner I, Astrada S, Bollati-Fogolín M, Garay HE, Reyes O. J Pept Sci. 2014 Nov;20(11):850-9. doi: 10.1002/psc.2676. Epub 2014 Jul 20. PMID: 25044757

The transcriptional activities and cellular localization of the human estrogen receptor alpha are affected by the synonymous Ala87 mutation. Fernández-Calero T, Astrada S, Alberti A, Horjales S, Arnal JF, Rovira C, Bollati-Fogolín M, Flouriot G, Marin M. J Steroid Biochem Mol Biol. 2014 Sep;143:99-104. doi: 10.1016/j.jsbmb.2014.02.016. Epub 2014 Mar 4. PMID: 24607813

Mucin-like peptides from Echinococcus granulosus induce antitumor activity. Noya V, Bay S, Festari MF, García EP, Rodriguez E, Chiale C, Ganneau C, Baleux F, Astrada S, Bollati-Fogolín M, Osinaga E, Freire T. Int J Oncol. 2013 Sep;43(3):775-84. doi: 10.3892/ijo.2013.2000. Epub 2013 Jun 28. PMID: 23817837

The Antitumor Peptide CIGB-552 Increases COMMD1 and Inhibits Growth of Human Lung Cancer Cells. Fernández Massó JR, Oliva Argüelles B, Tejeda Y, Astrada S, Garay H, Reyes O, Delgado-Roche L, Bollati-Fogolín M, Vallespí MG. J Amino Acids. 2013;2013:251398. doi: 10.1155/2013/251398. Epub 2013 Jan 16. PMID: 23401744

Direct role of Bardet-Biedl syndrome proteins in transcriptional regulation. Gascue C, Tan PL, Cardenas-Rodriguez M, Libisch G, Fernandez-Calero T, Liu YP, Astrada S, Robello C, Naya H, Katsanis N, Badano JL. J Cell Sci. 2012 Jan 15;125(Pt 2):362-75. doi: 10.1242/jcs.089375. Epub 2012 Feb 2. PMID: 22302990




Current profession

Current professional activities type: 
Research
PhD Student, Reseash Assistant