You are here

Member Profile

Membership type: full

Laure Stella Ghoma Linguissi

Country of origin: Congo, Republic Currently in: Congo, Republic, Brazzaville General field of specialization: Structural, Cell and Molecular Biology
Academic Background


2017 Doctorate Structural, Cell and Molecular Biology
2009 Master Engineering sciences
2004 Master Biological Systems and Organisms
Research and Profession

Current Research Activities

Structural, Cell and Molecular Biology

1. Molecular epidemiology of Mycobacterium tuberculosis in individuals suspected of pulmonary tuberculosis at the Pierre MOBENGO Central Army Hospital 2. Characterization of the resistance profile to Mycobacterium tuberculosis (MTB) anti-tuberculosis drugs in naive tuberculosis patients co-infected with TB / HIV consulted at Makelekele hospital 3. Surveillance of bovine tuberculosis and characterization of causative agents in a slaughterhouse in Brazzaville

Publications resulting from Research: 

1. LAURE STELLA GHOMA LINGUISSI, TANI SAGNA, SERGE THEOPHILE SOUBEIGA, LUC CHRISTIAN GWOM, CELINE NGUEFEU NKENFOU, DORCAS OBIRI-YEBOAH, ABDOUL KARIM OUATTARA, VIRGINIO PIETRA, JACQUES SIMPORE. Prevention of mother-to-child transmission (PMTCT) of HIV: a review of the achievements and challenges in Burkina-Faso. HIV/AIDS - Research and Palliative Care 2019:11 165–177
2. LAURE STELLA GHOMA LINGUISSI, VIOLAINE LUCACCIONI, MATTHEW BATES, ALIMUDDIN ZUMLA, FRANCINE NTOUMI. Achieving Sustainable Development Goals for HIV/AIDS in the Republic of Congo - Progress, Obstacles and Challenges in HIV/AIDS Health Services. Int J Infect Dis. 2018 Dec; 77:107-112. doi: 10.1016/j.ijid.2018.10.009. Epub 2018 Oct 17. PMID: 30342250
3. LAURE STELLA GHOMA LINGUISSI, ROBIN NOÉ ONGAGNA YOMBI, CÉLINE NGUEFEU NKENFOU, JEAN ROSAIRE IBARA. Knowledge of HIV/AIDS among students of the Faculty of Health Sciences, Brazzaville, Republic of Congo. American Journal of Epidemiology and Infectious Disease. 2018, Vol. 6 No. 1, 7-13. DOI: 10.12691/ajeid-6-1-2
4. GHOMA LINGUISSI LAURE STELLA, ROBIN NOÉ ONGAGNA YOMBI, MISSAMOU GERARD LEYNAU EVRARD AND LOUVOUANDOU SUZANNE. Knowledge of HIV/AIDS among General Practitioners in Health Facilities in Brazzaville in Republic of Congo. 2018. J Aids Hiv Inf 4(1): 102. ISSN: 2454-499X
5. LAURE STELLA GHOMA LINGUISSI. Evaluation of HIV knowledge among general practitioners in health centers in Brazzaville. International Journal of Scientific and Research Publications, Volume 8, Issue 5, May 2018 253 ISSN 2250-3153
6. LAURE STELLA GHOMA LINGUISSI, GWOM LC, NKENFOU CN, BATES M, PETERSEN E, ZUMLA A, ET AL. Health systems in the Republic of Congo: challenges and opportunities for implementing tuberculosis and HIV collaborative service, research, and training activities. Int J Infect Dis. 2017 Mar; 56:62-67. doi: 10.1016/j.ijid.2016.10.012
7. MALM S, LAURE STELLA GHOMA LINGUISSI, Emmanuel M. Tekwu, Jeannhey C. Vouvoungui, Thomas A. Kohl, Patrick Beckert, Anissa Sidibe, Sabine Rüsch-Gerdes, Igor K. Madzou-Laboum, Sylvie Kwedi, Véronique Penlap Beng, Matthias Frank, Francine Ntoumi, and Stefan Niemann. New Mycobacterium tuberculosis Complex Sublineage, Brazzaville, Congo. Emerg Infect Dis. 2017 Mar; 23(3): 423–429. doi: 10.3201/eid2303.160679. PMID: 28221129
8. LAURE STELLA GHOMA LINGUISSI, OUATTARA AK, NTAMBWE EK, MBALAWA CG, NKENFOU CN. Mobile applications: effective tools against HIV in Africa. Health Technol [Internet]. 28 juin 2017 [cité 6 mars 2018]; Disponible sur:
9. LAURE STELLA GHOMA LINGUISSI, NKENFOU CN. Epidemiology of viral hepatitis in the Republic of Congo: review. BMC Res Notes. 2017 Dec 2; 10(1):665. doi: 10.1186/s13104-017-2951-8. PMID: 29197421
10. LAURE STELLA GHOMA LINGUISSI, DAGENE FRUINOVY EBOUROMBI, ANISSA SIDIBE, THOMAS SERGE KIVOUELE, JEANNHEY CHRISTEVY VOUVOUNGUI, PIERRE POULAIN AND FRANCINE NTOUMI. Factors influencing acceptability of voluntary HIV testing among pregnant women in Gamboma, Republic of Congo. BMC Res Notes. 2015 8:652. Doi: 10.1186/s13104-015-1651-5
11. LAURE STELLA GHOMA LINGUISSI, BISSEYE C, POULAIN P, NTOUMI F, SIMPORE J. Prevention of Mother-to-Child HIV Transmission (PMTCT) in the Republic of Congo: Challenges to Implementation. J AIDS Clin Res. 2015;6 (9):503. doi:10.4172/2155- 6113.1000503
12. LAURE STELLA GHOMA LINGUISSI, VOUVOUNGUI CJ, POULAIN P, ESSASSA GB, KWEDI S, NTOUMI F. Diagnosis of smear-negative pulmonary tuberculosis based on clinical signs in the Republic of Congo. BMC Research Notes20158:804.
13. LAURE STELLA GHOMA LINGUISSI, NICAISE NDEMBI, CÉLINE NGUEFEU NKENFOU, PIERRE POULAIN AND FRANCINE NTOUMI. HIV-1 Genetic Diversity in the Republic of Congo: Seventeen Years in Review. JSM Microbiology. 3(2): 1025.
14. SIMPORE A, BISSEYE C, NAGALO BM, SANOU M, NÉBIÉ Y, GHOMA-LINGUISSI LS, DAHOUROU H, SAWADOGO B, DJIGMA F, OUATTARA S, PIETRA V, NICHOL J, SIMPORE J. Importance of extending the use of Polymerase chain reaction in the diagnosis of Venereal syphilis in a blood transfusion center in Burkina Faso, West Africa. Pan Afr Med J. 2014 May 15; 18:56. doi: 10.11604/pamj.2014.18.56.3850. PMID: 26113890
15. LAURE STELLA GHOMA LINGUISSI, MAYENGUE P, SIDIBÉ A, VOUVOUNGUI JC, MISSONTSA M, MADZOU-LABOUM I, ET AL. Prevalence of national treatment algorithm defined smear positive pulmonary tuberculosis in HIV positive patients in Brazzaville, Republic of Congo. BMC Res Notes. 2014; 7(1):578.
16. LAURE STELLA GHOMA LINGUISSI, BISSEYE C, SAGNA T, NAGALO BM, OUERMI D, DJIGMA FW, PIGNATELLI S, SIA JD, PIETRA V, MORET R, NIKIEMA JB, SIMPORE J. Efficiency of HAART in the prevention of mother to children HIV–1 transmission at Saint Camille medical centre in Burkina Faso, West Africa. Asian Pac J Trop Med. 2012 Dec; 5(12):991-4. doi: 10.1016/S1995-7645(12)60188-6. PMID: 23199720
17. LAURE STELLA GHOMA LINGUISSI, NAGALO BM, BISSEYE C, KAGONÉ TS, SANOU M, TAO I, BENAO V, SIMPORÉ J, KONÉ B. Seroprevalence of toxoplasmosis and rubella in pregnant women attending antenatal private clinic at Ouagadougou, Burkina Faso. Asian Pac J Trop Med. 2012 Oct; 5(10):810-3. doi: 10.1016/S1995-7645(12)60148-5. PMID: 23043921

Current profession

Current professional activities type: 
1. 2018-2022, ‘Assessment of the situation of Mycobacterium tuberculosis infection at Makélékélé base hospital in Brazzaville’ within the Central Africa clinical research Network on Tuberculosis, HIV/AIDS and Malaria (CANTAM) II project, EDCTP, 3,000,000,000 Euros. My responsibility as researcher is to perform experiments, analyse, interpret results and write articles. 2. 2018-2020 ‘Establishing a TB portal of Mycobacterium tuberculosis patients from tertiary care hospital in the Republic of Congo’ funded by Clinical Research and Development Fellowships (CRDF) Global (USA), €150,000. As senior researcher in this project, I participate in the enrollment of patients, the recording of data on the portal TB platform and the implementation of molecular diagnostic techniques. 3. 2020-2022 Contribution to the epidemiological surveillance of neglected tropical diseases in the Republic of Congo, the project PRC2018004 is funded by international atomic energy agency, €100,000. I have been appointed principal investigator and as such, I am responsible for overseeing the progress of the work. This project called PRC 6002 by the Congolese state is funded by the International Atomic Energy Agency (IAEA). IAEA funding only relates to the detection of nucleic acids, the acquisition of laboratory equipment, training and does not take into account epidemiological surveys, field surveys. The PRC project focuses on the molecular epidemiology of neglected tropical diseases.

Workshop and Conference Attended

2015 Cermel, Lambaréné, Gabon Regional workshop on laboratory methods for tuberculosis diagnosis
2019 Kigali, Rwanda 20th ICASA


Centre de Recherche Biomoléculaire Pietro Annigoni / Laboratoire de Biologie Moléculaire et de Génétique (CERBA/LABIOGENE)

Presentation given

Challenges in conducting HIV-TB clinical research in Central Africa: Experience from the Republic of Congo
kIgali, Rwanda
Event: EDCTP ICASA 2019 satellite symposium

Search form