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Membership type: full

Maham Ghouri

Country of origin: Pakistan Currently in: Pakistan, Karachi General field of specialization: Biological Systems and Organisms
Academic Background

Degrees

2020 Master Biological Systems and Organisms
2016 Undergraduate Biological Systems and Organisms
Research and Profession

Current Research Activities

Biological Systems and Organisms

Rheumatoid arthritis (RA) is an autoimmune joint disorder, that starts from small joints followed by tissue damage. The definite cause is still unknown, but some genetic and environmental factors may be involved. RA progression is initiated when macrophage appears and degrades cellular material by receptor-mediated endocytosis, against self cells and tissues. The research mainly focus on identification of susceptible genetic markers and role of immune regulators in the pathophysiology of RA. Being a M.Phil. / Ph. D. I have been involved in different research projects related to the field of Microbiology, and susceptible genetic marker among Leprosy patients

Research Keywords: 
Rheumatoid arthritis
IRAK2
LRP5
Animal model
health
Diseased animal model

Publications resulting from Research: 


Ghouri, M., Lateef, M., Liaquat, L., Zulfquar, A., Saleem, S., & Zehra, S. (2023). Decreased muscle strength in adjuvant-induced rheumatoid arthritis animal model: A relationship to behavioural assessments. Heliyon. https://doi.org/10.1016/j.heliyon.2023.e23264


Khan, A., Kulsoom, U. ., Ghouri, M., Fatima, S., Saleem, S., & Zehra, S. (2023). A Comparative Analysis of Inflammatory Markers and Disease Activity Score between Seropositive and Seronegative Rheumatoid Arthritis. BioSight, 4(3), 1–8. https://doi.org/10.46568/bios.v4i3.133.

Zehra, S., Ghouri, M., Jafari, H., Saleem, S., Fatima, S., & Azhar, A. (2022). Single nucleotide polymorphisms (rs3736228 and rs4988321) in low-density lipoprotein receptor-related protein-5 gene with predisposition to rheumatoid arthritis. Gene, 147025. Advance online publication. https://doi.org/10.1016/j.gene.2022.147025.

Ghouri M, Ismail M, Zaidi SA, Rehman S, Dahani A, et al. (2022) Multi-locus SNP analyses of interleukin 1 receptor associated kinases 2 gene polymorphisms with the susceptibility to rheumatoid arthritis. Plos One 17(5): e0268496. https://doi.org/10.1371/journal.pone.0268496.

Afshan, N., Ghouri, M., Hayat, A., & Nadeem, S. G. (2023). Molecular and biochemical characterization of solid waste biodegrading microbes isolated from municipal waste dump site. Acta Brasiliensis, 7(1), 7-13. https://doi.org/10.22571/2526-4338629.

Saleem, S., Zia, M., Siddiqui, F., Ghouri, M., Kulsoom, U., Kawal, S., Fatima, S., & Zehra, S. (2023). Hyperfunction variant rs708035 of interleukin 1 receptor-associated kinases 2 gene involved in the predisposition of leprosy infection. The Journal of Gene Medicine, e3473. Advance online publication. https://doi.org/10.1002/jgm.3473.

Fatima, A., Ghouri, M., & Sajid, T. (2018). Citrus Fruit Peels in Combating Various Foodborne Pathogens. RADS Journal of Biological Research & Applied Sciences, 9(2), 64-66.

Ghouri, M., Afshan, N., Javed, S., Fatima, A., Sadat, A., Chohan, A., & Nadeem, S. G. (2016). Physiochemical evaluation and liability of dromedary camels’ milk in combating various pathogens. African Journal of Microbiology Research, 10(41), 1739-1745.



Workshop and Conference Attended

March 10,14, and 17, 2023 Karachi Institute of Biotechnology and Genetic Engineering (KIBGE), University of Karachi. Research Proposal Writing-Secrets of Success and Reasons for Failures
August 29-31, 2022, The University of Tennessee, USA. Countering Biological Threats and Securing Dual Use Information, Technology and Expertise in Pakistan
The Muhammad Bin Rashid University of Medicine and Health Sciences Let’s break the chain of COVID-19 infection
June 22nd, 2020. Deep Exploration of the Genetic Dependencies of Antibiotic Function
February 20-22, 2019. Abbottabad University of Health and Sciences “Stem Cell Therapeutics” at TIBC, “Next Generation of Microbial Therapeutics
November 11, 2017, KIBGE, University of Karachi, Conducted by Sean Kaufman Doing Safety Together. A Day of Leadership in Biosafety

Affiliations

American Society of Microbiology
Pakistan Biological Safety Association – PBSA

Presentation given

December 29-30, 2023.
IRAK2 Gene Missense Variants D431E AND L392V: Prospective Genetic Markers for Rheumatoid Arthritis
KIBGE, University of Karachi
Event: Bio-safety: Navigating Biorisk Management in Pakistan
November 17-18, 2023.
Adjuvant-induced rheumatoid arthritis animal model: An approach to identify the role of immune mediators in the pathogenesis of disease
Pearl Continental, Lahore
Event: 44th Annual Conference of Pakistan Association of Pathologists (PAP) & 9th Joint Conference of Societies of Pathology
September 14-16, 2023.
Cultivating Genetically Modified Microbial Communities for the Biodegradation of Plastics: An Eco-Friendly Strategy to Enhance Environmental Sustainability
Hazara University, Mansehra
Event: All Pakistan Poster Competition, “From waste to worth: Mastering zero plastic use and innovation in plastic recycling under HEC Green Youth Movement The Green Youth Movement (GYM)”. An initiative of the Prime Minister's Youth Program.
JUNE 1-5, 2017
Physio-Chemical Evaluation and Liability of Dromedary Camel’s Milk in Combating Various Pathogens
New Orleans, LA.
Event: ASM MICROBES2017
Prizes, Grants and Awards

Other Awards

Jun 2021
Best Poster Presentation
Best Poster Presentation, Fourth International Conference on Biosciences organized by Biological Society of Pakistan (BSP) at Quaid-e-Azam University, June 15, 2021.
Sep 2023
First position in all Pakistan Poster Competition
First position in all Pakistan Poster Competition, “From waste to worth: Mastering zero plastic use and innovation in plastic recycling under HEC Green Youth Movement The Green Youth Movement (GYM)”. An initiative of the Prime Minister's Youth Program. Hazara University, Mansehra from September 14-16, 2023.
Nov 2023
First position (Medal) in oral presentation
First position (Medal) in oral presentation and Nominated for Prestigious Bukhari Gold Medal, Association of Molecular Pathology Pakistan (AMPP) at 44th Annual Conference of Pakistan Association of Pathologists (PAP) & 9th Joint Conference of Societies of Pathology, November 17-18, 2023.
Dec 2023
Third Position (Cash Prize) in poster presentation
Third Position (Cash Prize) in poster presentation at second OWSD Pakistan National Chapter Conference on “Bio-safety: Navigating Biorisk Management in Pakistan” dated December 29-30, 2023.

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