Member Profile
Membership type: full
Lerato Hlaka
Country of origin: South Africa Currently in: South Africa, Cape Town General field of specialization: Medical and Health Sciences incl Neurosciences-
Degrees
2015 Master Structural, Cell and Molecular Biology2011 Undergraduate Structural, Cell and Molecular Biology2019 Doctorate Medical and Health Sciences incl Neurosciences -
Current Research Activities
Medical and Health Sciences incl Neurosciences
Clinical sciences and Immunology. Immunology of Infectious diseases Pathogen/Host directed therapy for TB
Publications resulting from Research:
Lerato Hlaka*, Michael-Jon Rosslee*, Mumin Ozturk, Santosh Kumar, et al. Evaluation of Minor Groove Binders (MGBs) as novel anti-mycobacterial agents, and the effect of using non-ionic surfactant vesicles as a delivery system to improve their efficacy. Journal of Antimicrobial Chemotherapy. (2017).
Fraser J. Scott, Ryan J.O. Nichol, Abedawn I. Khalaf, Federica Giordani,…..Lerato Hlaka…et al. An evaluation of Minor Groove Binders as anti-fungal and anti-mycobacterial therapeutics. European Journal of Medicinal Chemistry. 136. 561-572. (2017).
Justin Komguep Nono; Hlumani Ndlovu; Nada Abdel Aziz; Thabo Mptoje; Lerato Hlaka; Frank Brombacher. Interleukin-4 Receptor Alpha is still required after Th2 polarization for the maintenance and the recall of protective immunity to Nematode infection. PLoS Neglected Tropical Diseases. 11. 1-17. (2017).
Justin Komguep Nono; Hlumani Ndlovu; Nada Abdel Aziz; Thabo Mptoje; Lerato Hlaka; Frank Brombacher. Host regulation of liver fibroproliferative pathology during experimental schistosomiasis via interleukin-4 receptor alpha. PLoS Neglected Tropical Diseases.11.1-22. (2017).
Current profession
Current professional activities type:Higher Education StudyPhD student,
Workshop and Conference Attended
2017 Dublin, Ireland Integrating Metabolism and Immunity (E4), Keystone Symposia on Molecular and Cellular Biology2017 Cape Town 6th South African Immunology Society Conference2017 Cape Town 7th African Flow Cytometry Workshop,2017 Cape Town Host-directed therapeutic strategies for infectious diseases. International Centre for Genetic Engineering and Biotechnology.2013 Parys Parasitological Society of Southern AfricaAffiliations
South African Women in Science and EngineeringSouth African Veterinary CouncilPresentation given
2017Metabolic control of Immune response by an L-amino acid oxidase at homeostasis and disease:IL-4i1Dublin, IrelandEvent: Integrating Metabolism and Immunity (E4), Keystone Symposia on Molecular and Cellular Biology2017Metabolic control of immune responses by IL-4i1 at steady state and disease.Cape TownEvent: Host-directed therapeutic strategies for infectious diseases. International Centre for Genetic Engineering and Biotechnology.2017IL-4i1 an L-amino acid oxidase is critical for homeostasisCape TownEvent: 6th South African Immunology Society Conference29-30 October 2019IL-4I1 REGULATES MACROPHAGE MEDIATED IMMUNE RESPONSES TO ACUTE MYCOBACTERIUM TUBERCULOSIS INFECTIONHyderabad, India.Event: TB Science: The 50th Union World Conference on Lung Health29-30 OCTOBER 2019MINOR GROOVE BINDERS AS NOVEL ANTI-MYCOBACTERIAL AGENTS AND THE EFFECT OF USING NON-IONIC SURFACTANT VESICLES AS A DRUG DELIVERY SYSTEMS FOR PATHOGEN-DIRECTED DRUG THERAPY FOR TUBERCULOSISHyderabad, India.Event: TB Science: The 50th Union World Conference on Lung Health -
Other Awards
Apr 2016SAMRC Internship Scholarship ProgrammeMar 2017WhiteHead Scientific Travel AwardJun 2017Mail and Guardian’s Top 200 Young South AfricansSep 2017Travel, accommodation and attendance Scholarship by SAIS to attend 6th South African Immunology Society ConferenceSep 2017Attendance scholarship by SAIS 7th African Flow Cytometry WorkshopOct 2018Keystone Symposia Global Health Travel AwardDec 2018L'Oreal-Unesco For Women in Science PhD Scholarship
