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Membership type: full

Olive Khaliq

Country of origin: South Africa Currently in: South Africa, Durban General field of specialization: Medical and Health Sciences incl Neurosciences
Academic Background


2020 Doctorate Medical and Health Sciences incl Neurosciences
Research and Profession

Current Research Activities

Medical and Health Sciences incl Neurosciences

The Association of ACE2 gene polymorphisms with the susceptibility of COVID-19 in South Africa. The SARS-CoV-2 coronavirus is currently a global pandemic and the epidemiology, pathophysiology and pathogenesis is still under immense investigations [41]. Recently, reports on COVID-19 gene mutations have been reported and a new variant (501Y.V2) has been discovered in South Africa [42]. Infection rates have increased since the initiation of the virus and with the rapid occurrence of mutations, it has become very difficult for clinicians to manage the infected population. Furthermore, it has been reported that the virus is more prevalent and aggressive in individuals of African ancestry , however, the scientific evidence on the reasons for this findings are unknown [43] The ACE2 receptor is known as the key entry port for the virus and studies have shown different levels of ACE2 expression in different racial groups and age groups [44, 45]. However, it is unclear whether the expression levels are altered by genetic mutations or environmental factors. Therefore there is an urgent need for further research on the pandemic to elucidate the association of genetic variations with COVID-19 in different racial groups.

Publications resulting from Research: 

1. The ACE2 expressions in males and females of different ages and racial groups in South Africa.

2. The association of ACE2 gene polymorphisms with COVID-19 in South Africa

Current profession

Current professional activities type: 
Currently employed as a research assistant at the University of KwaZulu-Natal in the Department of Obstetrics and Gynecology (Women's Health and HIV research group).

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