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Membership type: full

Ana Paula Mattos Areas Dau

Country of origin: Brazil Currently in: Brazil, São Paulo General field of specialization: Biological Systems and Organisms
Academic Background


2005 Doctorate Biological Systems and Organisms
Research and Profession

Current Research Activities

Biological Systems and Organisms

My research activities comprises the obtainance and functional studies of proteic virulence factors involved in bacterial pathogenic processes.

Publications resulting from Research: 

Research articles:
Staphylococcus aureus manganese transport protein C (MntC) is an extracellular matrix- and plasminogen-binding protein.
Salazar N, Castiblanco-Valencia MM, da Silva LB, de Castro Í, Monaris D, Masuda HP, Barbosa AS, Arêas AP.
PLoS One. 2014 Nov 19;9(11):e112730. doi: 10.1371/journal.pone.0112730. eCollection 2014. Erratum in: PLoS One. 2015;10(3):e0121192.
PMID: 25409527 Free PMC Article
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Select item 18403234
Nasal immunization of mice with Lactobacillus casei expressing the Pneumococcal Surface Protein A: induction of antibodies, complement deposition and partial protection against Streptococcus pneumoniae challenge.
Campos IB, Darrieux M, Ferreira DM, Miyaji EN, Silva DA, Arêas AP, Aires KA, Leite LC, Ho PL, Oliveira ML.
Microbes Infect. 2008 Apr;10(5):481-8. doi: 10.1016/j.micinf.2008.01.007. Epub 2008 Jan 20.
PMID: 18403234
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Select item 17542756
Intranasal vaccines for protection against respiratory and systemic bacterial infections.
Oliveira ML, Arêas AP, Ho PL.
Expert Rev Vaccines. 2007 Jun;6(3):419-29. Review.
PMID: 17542756
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Select item 16861686
Intranasal immunization with the cholera toxin B subunit-pneumococcal surface antigen A fusion protein induces protection against colonization with Streptococcus pneumoniae and has negligible impact on the nasopharyngeal and oral microbiota of mice.
Pimenta FC, Miyaji EN, Arêas AP, Oliveira ML, de Andrade AL, Ho PL, Hollingshead SK, Leite LC.
Infect Immun. 2006 Aug;74(8):4939-44.
PMID: 16861686 Free PMC Article
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Select item 16549380
Induction of systemic and mucosal immune response and decrease in Streptococcus pneumoniae colonization by nasal inoculation of mice with recombinant lactic acid bacteria expressing pneumococcal surface antigen A.
Oliveira ML, Arêas AP, Campos IB, Monedero V, Perez-Martínez G, Miyaji EN, Leite LC, Aires KA, Lee Ho P.
Microbes Infect. 2006 Apr;8(4):1016-24. Epub 2006 Jan 18.
PMID: 16549380
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Select item 16533983
DNA vaccines expressing pneumococcal surface protein A (PspA) elicit protection levels comparable to recombinant protein.
Ferreira DM, Miyaji EN, Oliveira ML, Darrieux M, Arêas AP, Ho PL, Leite LC.
J Med Microbiol. 2006 Apr;55(Pt 4):375-8.
PMID: 16533983
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Select item 16487311
DNA vaccines based on genetically detoxified derivatives of pneumolysin fail to protect mice against challenge with Streptococcus pneumoniae.
Ferreira DM, Arêas AP, Darrieux M, Leite LC, Miyaji EN.
FEMS Immunol Med Microbiol. 2006 Mar;46(2):291-7.
PMID: 16487311 Free Article
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Select item 15908419
Intradermal immunization of mice with cholera toxin B-pneumococcal surface protein A fusion protein is protective against intraperitoneal challenge with Streptococcus pneumoniae.
Arêas AP, Oliveira ML, Miyaji EN, Leite LC, Ho PL.
Infect Immun. 2005 Jun;73(6):3810-3. No abstract available.
PMID: 15908419 Free PMC Article
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Select item 15358234
Expression and characterization of cholera toxin B-pneumococcal surface adhesin A fusion protein in Escherichia coli: ability of CTB-PsaA to induce humoral immune response in mice.
Arêas AP, Oliveira ML, Miyaji EN, Leite LC, Aires KA, Dias WO, Ho PL.
Biochem Biophys Res Commun. 2004 Aug 13;321(1):192-6.
PMID: 15358234
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Select item 15213177
Multiserotype protection of mice against pneumococcal colonization of the nasopharynx and middle ear by killed nonencapsulated cells given intranasally with a nontoxic adjuvant.
Malley R, Morse SC, Leite LC, Areas AP, Ho PL, Kubrusly FS, Almeida IC, Anderson P.
Infect Immun. 2004 Jul;72(7):4290-2.
PMID: 15213177 Free PMC Article
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Select item 12182829
Synthesis of cholera toxin B subunit gene: cloning and expression of a functional 6XHis-tagged protein in Escherichia coli.
Arêas AP, Oliveira ML, Ramos CR, Sbrogio-Almeida ME, Raw I, Ho PL.
Protein Expr Purif. 2002 Aug;25(3):481-7.
PMID: 12182829
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Current profession

Current professional activities type: 


Member of Brazilian Society of Microbiology
Prizes, Grants and Awards

Other Awards

Dec 2006
Honorable mention and first place in Research for SUS, Health Ministry, Brazil
The group I participated as long as I developed my PhD project received an honorable mention and the first place in a prize conceded by Brazilian Health Ministry. The aim of the prize was to laureate significant contribution of scientific works to Public Health System. I was the first autor of the article which received the honorable mention and a co-author of the work laureated in this cathegory.