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Membership type: full

Priyani Ashoka Paranagama

Country of origin: Sri Lanka Currently in: Sri Lanka, Weliveriya General field of specialization: Chemical Sciences
Academic Background

Degrees

1994 Doctorate Chemical Sciences
Research and Profession

Current Research Activities

Chemical Sciences

Research on bioactivity of natural products


Publications resulting from Research: 


1. Nusra, M. S. F., Amarasinghe, L. D., Udukala, D. N. and Paranagama, P. A. (2020) Pheromone baited biopesticide for control of Leucinodes orbonalis Guenee in brinjal plant , Frontiers in Bioscience, Elite, 12, 35-47.

2. Wickramarachchi P.A.S.R., Samanthi K.A.U., Paranagama, P. (2019) A new antioxidant active compound from the endolichenic fungus, Penicillium citrinum inhabiting the lichen, Parmotrema sp. International Journal of Pharmaceutical Science and Research, 10(7), 1000 – 1009.

3. Kuruppu, A.I., Paranagama, P., De Silva, R., (2019) Anticancer potential of natural products: a review focusing on Sri Lankan plants, frontiers in Bioscience, scholar, 11, 161-177.
4. Kuruppu, A.I., Paranagama, P., Goonasekara, C., (2019) Medicinal plants commonly used against cancer in traditional medicine formulae in Sri Lanka, Saudi Pharmaceutical Journal, doi: https://doi.org/ 10.1016/j.jsps.2019.02.004
5. Nusra, M. S. F., Amarasinghe, L. D., Udukala, D. N. and Paranagama, P. A. (2018) Host plant volatile-mediated attraction of Leucinodes orbonalis Guenee, Proceeding of the conference Conference SLCARP International Agricultural Research Symposium 2018, pp 44, ISBN : 978-955-9224-69-3
6. Maduranga K, Attanayake RN, Santhirasegaram S, Weerakoon G, Paranagama PA (2018) Molecular phylogeny and bioprospecting of Endolichenic Fungi (ELF) inhabiting in the lichens collected from a mangrove ecosystem in Sri Lanka. PLoS ONE 13(8): e0200711. https://doi.org/ 10.1371/journal.pone.0200711
7. A. Kurian, G. Thiripuranathar, P.A. Paranagama (2017) Determination of total phenolic content and antioxidant activity of Borassus flabeliffer LINN. Fruit pulp collected from several parts of Sri Lanka, International Journal of Pharmaceutical Science and Research, 8(6), 2701 - 2705.

8. A. Kuganesan, G.Thirupuranathar, A.N.Navaratne, P.A.Paranagama (2017) Antioxidant and anti-inflammatory activities of peels,pulps and seed kernels of three common mango (Mangifera Indica L) varieties in Sri Lanka, International Journal of Pharmaceutical Science and Research, 8(1), 70-78.

9. Manuha,M.I., Nageeb, B.M., Iqbal, N.Z. and Paranagama, P.A. (2017) Assessment of antioxidant potential using total phenolic content and DPPH assay of a Sri Lankan ‘spice’ mixture used to impair obesity, International Journal of Multidisciplinary Education and Research, pp 34-36.

10. Senanayake, P.D., Mohotti, K., Paranagama, P.A. (2016) Identification and substrate utilization of fungi associated with low country live wood termite, Glyptotermes dilatatus Bugnion & Popoff and the host plant, Camellia sinensis L.O.Kuntze, Journal of the National Science Foundation, 44(2), 175-184.

11. Wickramarachchi P.A.S.R., Samratunge I. N., Kaushalya C.H.T.C., Rasangika W.P.M. and Paranagama P.A. (2016) Activity of chitosan films enriched with essential oil of Alpinia malaccensis rhizome against three common food pathogens, Journal of the National Science Foundation, 44(2), 129-135.

12. Senanayake, P.D., Mohotti, K., Paranagama, P.A. (2016) Volatile constituents of tea stems (Camellia sinensis L.O.Kuntze) as semiochemicals to attract low country live wood termite, (Glyptotermes dilatatus Bugnion&Popoff) in Sri Lanka, Journal of the National Science Foundation, 44 (1), 33-42.

13. Senanayake, P.D., Mohotti, K., Paranagama, P.A. (2016) Bioactive constituents of wood rot extract of tea, Camellia sinensis L.O. Kuntze against alates of low country live wood termite, Glyptotermes dilatatus Bugnion & Popoff (Isoptera: Kalotermitidae), SpringerPlus 2015, 4:711, doi:10.1186/s40064-015-1513-6.

14. Samanthi K.A.U., Wickramaarachchi S., Wijeratne E. M. K., Paranagama P. A. (2015) Two New Bioactive curvularin derivatives from Curvularia trifolii, an endolichenic fungus isolated from Usnea sp., in Sri Lanka, Journal of the National Science Foundation of Sri Lanka, 43 (3): 217-224, DOI: http://dx.doi.org/10.4038/jnsfsr.v43i3.7950


15. Samanthi K.A.U., Wickramaarachchi S., Wijeratne E. M. K., Paranagama P. A. (2015) Two New bioactive polyketides from Penicillium citrinum, endolichenic fungus isolated from Parmotreama sp., in Sri Lanka, Journal of the National Science Foundation, 42(02), 119-126.

16. Jaysisri, AAP, Senanayake, SP, Paranagama, P A, Amarasinghe, APG (2015), Phenetic analysis and phytochemical screening of medicinally important Albizia spp. in Sri Lanka, Ceylon Journal of Science (Bio. Sci.), 44 (2): 85-90.

17. Jayasiri, A.P.A., Paranagama.P. , Senanayake, S.P. , Amarasinghe, A.P.G. (2014) In-vitro anti- inflammatory activity of stem bark extract of Sri Lankan Albizia lebbeck (Fabaceae), Sri Lanka Journal of Indigenous Medicine, Institute of Indigenous Medicine, University of Colombo, Rajagiriya, Sri Lanka.

18. Jaysisri, AAP, Senanayake, SP, Paranagama, P A, Amarasinghe, APG (2013) Preliminary phytochemical screening of the medicinal plant Adenanthera pavonina and its morphological variation, Sri Lanka Journal of Indigenous Medicine, 03(01), 152-156.

19. Manuha, MI, Iqbal, NZ, Nageeb, BM, Paranagama, P. A. (2013) A study on the correlation between Body Mass Index of overweight / obese, Total Physical Activity and Cardiovascular risk factors with special reference to dyslipidaemia in adult women, Sri Lanka Journal of Indigenous Medicine, 03(01), 157-163.

20. Manuha, M.I., Nageeb, B.M., Iqbal, N.Z. and Paranagama, P.A. (2013) Association of Physical Activity and Sedentary Lifestyle with Overweight and Obesity among Adult Women in Sri Lanka, World Applied Science Journal, 24 (6): 724-731, 2013

21. Kannangara, B.T.S.D.P., Rajapaksha, R. S. C. G. and Paranagama, P.A. (2009) Nature and bioactivities of endolichenic fungi in Pseudocypellaria sp., Parmotrema sp., and Usnea sp.at Hakgala montane forest in Sri Lanka, Journal of Letters in Applied Microbiology, 48, 203-209.

22. Wijeratne, E. M. K.; Paranagama, P. A.;Burns, A. M.; Marron, M. T.; Gunatilaka, M. K.; Arnold, A. E; Gunatilaka, A. A. L. (2008) Sesquiterpene Quinones and Related Metabolites from Phyllosticta spinarum, A Fungal Strain Endophytic in Platycladus orientalis of the Sonoran Desert, J. Nat. Prod., 71, 218 – 222.

23. Paranagama, P. A., Wijeratne, E. M., and Gunatilaka, A. A. L. (2007) Uncovering Biosynthetic Potential of Plant-Associated Fungi: Effect of Culture Conditions on Metabolite Production by Paraphaeosphaeria quadriseptata and Chaetomium chiversii, J. Nat. Prod. 70, 1939 - 1945.

24. Paranagama, P. A.; Wijeratne, E. M. K.; Burns, A. M.; Marron, M. T.; Gunatilaka, M. K.; Arnold, A. E; Gunatilaka, A. A. L. Heptaketides from Corynespora sp. (2007) Inhabiting the Cavern Beard Lichen, Usnea cavernosa: First Report of Metabolites of an Endolichenic Fungus, J. Nat. Prod., 70, 1700–1705.

25. Wijeratne, E. M., Paranagama, P. A. and Gunatilaka, A. A. L. (2006): Five new isocoumarins from Sonoran desert plant-associated fungal strains Paraphaeosphaeria quadriseptata and Chaetomium chiversii, Tetrahedron, 62, 8439 – 8446.


Essential oils and Biopesticides

26. Balachandra, B. A. H. E., Pathirathna, P.U. and Parangama, P. A. (2011) Control of stored grain pest, Callosobruchus maculatus (F.) (Coleoptera: Bruchidae) using the essential oil isolated from Plectranthus zeylanicus, Natural Products Research, 1-4.

27. Paranagama, P. A. and Gunasekera, J. A. (2011) The Efficacy of the Essential Oils of Sri Lankan Cinnamomum zeylanicum fruit and Micromelum minutum leaf against Callosobruchus maculatus (F.) (Coleoptera: Bruchidae), Journal of Essential Oil Research, 23,75 – 82.

28. Rubasinghe, G. R.S., Paranagama, P. A. and Abeywickrama, K.P. (2006) Physiochemical changes of stored cowpea, Vigna unguiculata treated with selected essential oils to control cowpea bruchid, Callosobruchus manculatus (F.), Journal of Food Agriculture and Environment,04, 41-44.

29. Abeywickrama, K.P., Adhikari, A.C.C.K., Paranagama, P.A. and Gamage, C.S.P. (2006): The efficacy of essential oil of Alpinia calcarata (Rosc.) and its major constituent, 1,8-cineole, as protectants of cowpea against Callosobruchus manculatus(F.) (Coloeptera; Bruchidae), Canadian Journal of Plant Science, 821-827.

30. Paranagama, P.A. and Ekanayake, E.M.K.S. (2004): Repellent properties of essential of Alpinia calcarata ROSC. against American cockroach, Periplenata americana, Journal of National Foundation,32, (1&2), 1-12.

31. Paranagama, P.A., Connolly, J.D., Strang, R.H.C. (2004):Azadirachtin effects protein synthesis in fat body, haemolymph, ovary and mid gut of the locusts, Schistocerca gregaria, Journal of National Science Foundation, 32, (1&2), 13-28.

32. Paranagama, P.A, Abeysekera, K.H.T., Nugeliyadde, L. and Abeywickrama, K.P. (2004): Repellency and toxicity of four essential oils to Sitophilusoryzae L. (Coleptera; Curculionidae), Journal of National Science Foundation, 32 (3 & 4), 127-138.

33. Paranagama, P.A, Abeysekera, K.H.T., Nugeliyadde, L. and Abeywickrama, K.P. (2003): Fungicidal and antiaflatoxigenic effects of the essential oil of Cymbopogon citratus against Aspergillus flavus Link. Isolated from stored rice, Letters in Applied Microbiology, 37(1), 86-90.

34. Paranagama, P.A, Abeysekera, K.H.T., Nugeliyadde, L. and Abeywickrama, K.P. (2003): Effect of the essential oils of Cymbopogon citratus, Cymbopogon nardus and Cinnamomum zeylanicumon pest incidence and grain quality of rough rice (paddy) stored in an enclosed seed box, Journal of Food Agriculture & Environment, 01(2),134-136.

35. Paranagama, P.A.,Adhikari, A. A. C. K., Abeywickrama, K. P. and Bandara , K. A. N. P. (2003): Deterrent effects of some Sri Lankan essential oils on oviposition and progeny production of the cowpea bruchid; Callosobruchus manculatus (F.) (Coloeptera; Bruchidae), Journal of Food, Agriculture & Environment, 01(2),254-257.

36. Paranagama, P.A., Adhikari, A. A. C. K., Abeywickrama, K. P. and Bandara , K. A. N. P. (2003): Evaluation of volatile constituents of neem, Azadirachta indica A. Juss. (Neem) leaf extract against Callosobruchus maculatus(F.). Journal of the National Science Foundation, 31(3&4), 445-458.

37. Paranagama, P.A. Connolly, J. D., Strang, R.H.C. (2003): Effect of azadirachtin on incorporation of 35S-cysteine into peptides in the brain and corpus cardiacum in the locusts, Schistocerca gregaria, Journal of National Science Foundation, 31(3&4), 459-471.

38. Paranagama, P.A,Abeysekera, K.H.T., Nugeliyadde, L. and Abeywickrama, K.P. (2002): Bioactivity of leaf volatiles of Azadirachta indica A. and Murrayako enigii(spreng) agaomst Sitophilus orysae (L.) (Coleoptera: Curculionidae), Tropical Agricultural Research and Extension, 5(1&2), 17-21.

39. Paranagama, P.A.,Adhikari, A. A. C. K., Abeywickrama, K. P. andBandara , K. A. N. P. (2002): Toxicity and repellent activity of essential oils of Cymbopogon citratus (DC) Stapf and Murraya koinigii Spreng against Callosobruchus maculatus (F.) (Coleoptera; Bruchidae). Tropical Agricultural Research and Extension, 5(1&2), 22-28.

40. Jayaratne, K.H.T., Paranagama,P.A., Nugeliyadde, L. and Abeywickrama, K.P. (2002): Inhibition of Aspergillus flavus (Link) and aflatoxin formation by the essential oils of Cinnamomum zeylanicum (L.) leaf and Cymbopogon nardus Rendle, Tropical Agricultural Research, 14,148-153.

41. Adhikari, A. A. C. K., Paranagama, P. A., Abeywickrama, K. P. and Bandara, K. A. N. P. (2002):Behavioral studies of Cowpea brchid, Callosobruchus maculatus (F.) against Volatile extracts from leaves of Lemongrass (Cymbopogon citratus), Neem (Azadirachta indica) and curry leaf (Murraya koenigii). Tropical Agricultural Research, 14, 138-147.

42. Paranagama, P.A., Kodikara, K.A.B.C.H., Nishantha, H.M.I. and Mubarak, A.M. (2002): Effect of azadirachtin on growth and activity of mid-gut enzymes of cockroach Periplaneta americana, Journal of National Science Foundation in Sri Lanka, 29 (1&2), 69-70.

43. Paranagama, P.A.,Jayathilake, G.S., Jayawardene, A. L., Mubarak, A. M., Senanayeke, U. M., and Wimalasena, S. (2002) Analysis of volatile oil in the leaves of Murraya koenigii, Malaysian Journal of Tropical Medicinal Plants, ,03:02, 187 – 180.

44. Paranagama, P.A., Jayathilake, G. S., Jayawardene, A.L., Mubarak, Senanayeke, U.M. and Wimalasena, S. (2001): A comparison of volatile constituents of Cinnamon bark, leaf, root bark and fruit in Sri Lanka, Journal of National Science Foundation in Sri Lanka, 29 (3&4), 147-153.

45. Paranagama,P.A., Lovell, H., Denholm, A.A., Ley, S.V., Connolly, J.D. and Strang, R.H.C. (1993): Uptake retention metabolism and excretion of 22,233H-dihydroazadirachtin in schistocerca gregaria, Journal of Insect Physiology, 39 (11), 935-943.

46. Channa Jayasumana, Saranga Fonseka, Ashvin Fernando, Kumudika Jayalath, Mala Amarasinghe, Sarath Gunatilake, Sisira Siribaddana and Priyani Paranagama (2015) Phosphate fertilizer is a main source of arsenic in areas affected with chronic kidney disease of unknown etiology in Sri Lanka, SpringerPlus, http://dx.doi.org/10.1186/s40064-015-0868-z, DOI:10.1186/s40064-015-0868-z.

47. Channa Jayasumana, Priyani Paranagama, Saranga Fonseka, Mala Amarasinghe, Sarath Gunatilake and Sisira Siribaddana (2015) Presence of arsenic in Sri Lankan rice, International Journal of Food Contamination (2015) 2:1, DOI 10.1186/s40550-015-0007-1.

48. Jayasumana, M.A.C.S., Paranagama, P.A., Agampodi, S., Wijewardane, K.M.R.C., Gunatilake, S. and Siribaddana, S. (2015) Drinking well water and occupational exposure to Herbicides is associated with chronic kidney disease, in Padavi-Sripura, Sri Lanka, Environmental Health, 14(06), DOI: 10.1186/1476-069X-14-6

49. Paranagama, P. A. (2013) Potential link between ground water hardness, arsenic content and prevalence of CKDu, Full paper of the Proceedings of the Symposium on“Chronic Kidney Disease of uncertain origin (CKDu): a scientific basis for future action”, National Academy of Sciences of Sri Lanka, http://nas-srilanka.org/?page_id=202

50. Paranagama, P A (2013) Global Environmental Impacts of Agriculture, Requirement for sustainable agricultural practices to save the world, Chemistry in Sri Lanka, 30 (03), 43-51

51. Jayasumana, M.A.C.S., Paranagama, P.A.,Amarasinghe, M. D., Wijewardane, K.M.R.C., Dahanayake, K.S., Fonseka, S.I., Rajakaruna, K.D.L.M.P., Mahamithawa, A.M.P., Samarasinghe, U.D., Senanayake, V.K. (2013) Possible link of Chronic arsenic toxicity with Chronic Kidney Disease of unknown etiology in Sri Lanka, Journal of Natural Sciences Research, 3(1), 64-73.

52. Jayasumana, MACS, Fonseka, SI, Fernando, A, Jayalath, K, Amarasinghe, MD, Paranagama, PA, (2014) Presence of arsenic in agrochemicals and their association with the agricultural kidney disease in Sri Lanka, The Journal of Toxicology and Health, 104, 352-361.https://sites.google.com/site/photonjournalpeer/home/the-journal-of-toxicology-and-health



Current profession

Current professional activities type: 
Administration
Director, Institute of Indigenous Medicine, University of Colombo, Sri Lanka President, Institute of Chemistry, Ceylon, Sri Lanka

Workshop and Conference Attended

2019 Taiwan Asian Chemical Congress in Taiwan 2019
2019 France • IUPAC conference 2019 in France
2018 Australia Asian Chemical Congress 2018 in Australia

Affiliations

Institute of Chemistry Ceylon

Presentation given

2019
BIOPROSPECTING OF ENDOLICHENIC FUNGI FROM MANGROVE ECOSYSTEM OF PUTTALAM LAGOON IN SRI LANKA
France
Event: IUPAC congress
Prizes, Grants and Awards

Other Awards

Dec 2019
• Senate award, 2019 for the publication in peer review journal
Senate award was given for publications made in peer reviewed index journals
May 2017
SUSRED award, 2017, National Science Foundation, Sri Lanka
This award was given for supervision of postgraduate degree which was completed within 3 years
Jan 2016
Vice Chancellors Award – 2016
for the highest amount of External Research Grant funding in the Faculty of Science in 2015
Jan 2015
• Dr. C. L. De Silva Gold Medal -2015 for outstanding research contribution in chemical sciences • Merit award from National Research Council, 2014. • Silver medal was awarded to the paper presented at the annual research symposium of the college of For
• Dr. C. L. De Silva Gold Medal -2015 for outstanding research contribution in chemical sciences • Merit award from National Research Council, 2014. • Silver medal was awarded to the paper presented at the annual research symposium of the college of Forensic Pathologist of Sri Lanka, 25th February 2012. • Presidential awards, 2009 & 2008 • Professor M U S Sultanbawa Memorial Oration Gold Medal Award – 2008 • Merit certificate for Scientific Research at Young Scientists Forum – 2007, National Science and Technology Commission, Ministry of Science and Technology.

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