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Membership type: full

Prof. Dr. Shagufta Perveen

Country of origin: Pakistan Currently in: Saudi Arabia, Riyadh General field of specialization: Chemical Sciences
Academic Background


2009 Doctorate Chemical Sciences
Research and Profession

Current Research Activities

Biological Systems and Organisms

Extraction, fractionation, isolation, 1D 2D NMR identification, derivatization, bioactivity of important secondary metabolites. Microbial transformation of important medicinal compounds isolated from different natural sources. Bioassay guided isolation of natural metabolites. HPLC based determination. HPTLC standardization. Metabolomics. Plants endophyte.

Publications resulting from Research: 

List of Publications (International, Chapters & Books Editor)

I. Book Editor:
3- Shagufta Perveen*, Areej Mohammad Al-Taweel "Terpenes and Terpenoids", 2021, Terpenes and Terpenoids in press with Intech Open. (1)
2- Shagufta Perveen*, Areej Mohammad Al-Taweel "Pharmacognosy - Medicinal Plants". Intech Open, 2019, ISBNs: 978-1-83880-610-1, 978-1-83880-611-8. (1)
1- Shagufta Perveen*, Areej Mohammad Al-Taweel "Terpenes and Terpenoids", 2018, Terpenes and Terpenoids," ISBN 978-953-51-6013-7. (1)

II. Book Chapters:
5- Shagufta Perveen*, "Terpenes and Terpenoids", 2021, Chapter 1," in press Intech Open. (1)
4- Shagufta Perveen*, " Pharmacognosy - Medicinal Plants ", 2019, Chapter 1. (1)
3- Shagufta Perveen*, Areej Mohammad Al‑Taweel, Green Chemistry and synthesis of anticancer molecules, Intech publisher, ISBN 978-953-51-3848-8, Chapter 4, pages 51-72, 2018. (1)
2- Shagufta Perveen*, "Terpenes and Terpenoids", 2018, Chapter 1," ISBN 978-953-51-6013-7. (1)
1- Shagufta Perveen*, Areej Mohammad Al‑Taweel, Phenolic Compounds Natural Sources, Importance & Applications”, Chapter 2: Phenolic Compounds from the Natural Sources and their Cytotoxicity. Intech publisher, 2017, pages 28-60. (1)

III. ISI Index Journals Research Papers: (Impact Factor 144)
90- Raha Orfali, Shagufta Perveen*, Hanan Y. Aati, Perwez Alam, Omar M. Noman, Javier Palacios, Bayan Salem S. Al-Kurbi, Areej M. Al-Taweel, Afsar Khan, Rashad Mehmood, Shabana Iqrar Khan. High-Performance Thin-Layer Chromatography for Rutin, Chlorogenic Acid, Caffeic Acid, Ursolic Acid, and Stigmasterol Analysis in Periploca aphylla Extracts. Separation, 8, 44. 1-12, 2021. IF: 2.0. (1)

89- Areej Mohammad Al-Taweel, Shagufta Perveen*, Saleh Ibrahim Alqasoumi, Raha Orfali, Hanan Y. Aati, Shahnaz, Ebtesam Nasser Alsultan, Bandar Alghanem, Hayat Shaibah. New flavane gallates from the aerial part of an African/Arabian medicinal Plant Plicosepalus curviflorus by LC-MS and NMR based molecular characterization. Journal of King Saud University-Science. 33, 2021, 101289. IF: 3.82. (1)

88- Raha Orfali, Mostafa E. Rateb, Hossam M Hassan, Mona Alonazi, Mokhtar R. Gomaa, Noura Mahrous, Mohamed GabAllah, Ahmed Kandeil, Shagufta Perveen, Usama Ramadan Abdelmohsen, Sinapic acid suppresses SARS CoV-2 replication possibly by targeting its envelope protein. Antibiotics, 2021, 10, 420. IF: 3.9. (3) 3

87- Raha Orfali, Mahmoud A. Aboseada, Nada M. Abdel-Wahab, Hossam M. Hassan, Shagufta Perveen, Fuad Ameen, Eman Alturki , Usama Ramadan Abdelmohsen. Recent updates on the bioactive compounds of the marine-derived genus Aspergillus. RSC Advance, 2021 (Accepted). (3)

86- Raha Orfali, Shagufta Perveen*, Muhamamd F. Khan, Atallah F. Ahmed, Sobia Tabassum, Paolo Luciano, Giuseppina Chianese, and Orazio Taglialatela-Scafati. Asporychalasin, a bioactive cytochalasan with an unprecedented 6/6/11 skeleton from the Red Sea sediment Aspergillus oryzae. Bioorganic Chemistry. 2021 (Under review). IF: 4.8. (1)

85- Hanan Y. Aati, Shagufta Perveen*, Raha Orfali, Muhammad Farooq, Areej M. Al-Taweel, Fahd A. Nasr, Maged S. Abdel-Kader. New cytotoxic guaiane type sesquiterpenoids from the leaves of Anvillea garcinia. Plants. 2021 (Under review). (1)

84- Raha Orfali, Shagufta Perveen*, Areej Al-Taweel, Hannan Ati, Atallah F. Ahmed, Muhammad Farooq, and Orazio Taglialatela-Scafati, Illudalane sesquiterpenes from the Red Sea marine fungus Aspergillus oryzae. Marine Drugs. 2021 (Under review). (1)

83- Maryam Sarwar, Siraj Din, Rehman Ullah, Raha Orfali, Hanan Aati, Shagufta Perveen*. Pharmacological Screening of Rhamnus triquetra to find out its Antipyretic, Analgesic, Antidiarrheal and Sedative potential. Evidence-Based Complementary and Alternative Medicine. (1)

82- Raha Orfali, Shagufta Perveen*, Hanan Aati; Areej Al-Taweel. nCOVID-19 Outcomes on curfews and lockdown: Precautionary decisions in Saudi Arabia. Health Policy and Technology. 2020 (Under review). (1)

81- Hanan Ati, Shagufta Perveen*, Raha Orfali, Juergen Wanner, Sultan Yahya, Areej Al- Taweel. Antimicrobial activity of Volatile Constituents Extracted by Hydrodistillation and Headspace Solid-Phase Microextraction Methods from Different Parts of Saudi Anethum graveolens L. (Dill) Growing in Jazan Province. Plants. (submitted). (1)

80- Rashad Mehmood, Sajjad Hussain Sumrra, Muhammad Imran, Ahmad Irfan, Mohammed A. Assiri, Rasool Bakhsh Tareen, Shagufta Perveen. Phytochemical, pharmacological and in silico studies on Teucrium stocksianum Bioss. Theoretical Chemistry Accounts. (Under review). (3) 4

79- Raha Orfali, Shagufta Perveen*, Areej Al-Taweel, Atallah F. Ahmed, Najwa Majrashi, Khulud Alluhay, Afsar Khan, Paolo Luciano, Orazio Taglialatela-Scafati. Penipyranicins A-C, Antibacterial Methylpyran Polyketides from a Hydrothermal Spring Sediment Penicillium sp. Journal of Natural Products, 83, 12, 3591–3597 2020. IF: 4.25. (1)

78- Jawaher Alqahtani; Formisano, Carmen; Chianese, Giuseppina; Luciano, Paolo; Stornaiuolo, Mariano; Shagufta Perveen*, Orazio Taglialatela-Scafati, Glycosylated Polyphenols and an Unprecedented Diacid from the Saudi Food Plant Cissus rotundifolia. Journal of Natural Products, 83, 11, 3298-3304, 2020. IF: 4.25. (1)

77- Hanan Y. Aati, Shagufta Perveen*, Raha Orfali, Areej M. Al-Taweel, Sultan Yahya, Juergen Wanner Afsar Khan, Rashad Mehmood. Chemical composition and antimicrobial activity of the essential oils of Artemisia absinthium, Artemisia scoparia, and Artemisia sieberi grown in Saudi Arabia. Arabia Journal of Chemistry, 2020. IF: 476. (1)

76- Roberto Ybañez-Julca, Daniel Asunción-Álvarez, Iván Quispe-Diaz, Javier Palacios, Jorge Bórquez, Mario J. Simirgiotis, Shagufta Perveen, Chukwuemeka R. Nwokocha, Fredi Cifuentes, Adrián Paredes. Metabolomic Profiling of Mango (Mangifera indica Linn) Leaf Extract and Its Intestinal Protective Effect and Antioxidant Activity in Different Biological Models. Molecules, 25, 5149, 2020. IF: 3.06. (3)

75- Shagufta Perveen*, Jawaher Alqahtani, Raha Orfali, Areej Mohammad Al- Taweel, Hasan Soliman Yusufoglu, Maged Saad Abdel-Kader, Afsar Khan, Orazio Taglialatela-Scafati, Antibacterial and Antifungal Sesquiterpenoids from Aerial Parts of Anvillea garcinii. Molecules. 2020, 25, 1730. IF: 3.06. (1)

74- Raha Orfali, Weaam Ebrahim, Shagufta Perveen, Najwa Mohammad Mejrashi, Khulud Alluhayb, Sherif S. Ebada, Cytotoxic Secondary Metabolites from Mangrove-Rhizosphere-Associated Fungus Emericella sp. Strain SWR1718, Journal of King Saud University – Science 32 (2020) 2656–2661. IF: 2.835. (2) 5

73- Shagufta Perveen*, Raha Orfali, Muhammad Shafiq ul Azam, Hanan Y. Aati, Areej Mohammad Al-Taweel. Coronavirus nCOVID-19: A Pandemic Disease and the Saudi precautions. Saudi Pharmaceutical Journal. 28, 2020, 888-897. IF: 2.88. (1)

72- Raha Orfali, Mahmoud Abdel-Azim, Mohammad Hassan, Shagufta Perveen, Arwa Bin-Swuilih, Hanan Abu Al-Ala’a, Saja Bane-jamea, Nada Zaidan. Production of a Biopesticide on Host and Non-Host Serine Protease Inhibitors for Red Palm Weevil in Palm Trees. Saudi Journal of Biological Sciences, 27, 2020, 2803-2808. IF: 2.802. (4)

71- Shagufta Perveen*, Ian H. Sadler, Raha Orfali Areej Mohammad Al-Taweel, Lorna Murray, Stephen C. Fry, Montbresides A-D: antibacterial p-coumaroyl esters of a new sucrose-based tetrasaccharide from Crocosmia × crocosmiiflora (montbretia) flowers, Fitoterapia. 2019 Nov;139:104377. doi: 10.1016/j.fitote.2019.104377. 2.431 (1)

70- Al-Hamoud GA, Saud Orfali R, Perveen S, Mizuno K, Takeda Y, Nehira T, Masuda K, Sugimoto S, Yamano Y, Otsuka H, Matsunami K. Lasianosides A-E: New Iridoid Glucosides from the Leaves of Lasianthus verticillatus (Lour.) Merr. and Their Antioxidant Activity. Molecules. 2019 Nov 5;24(21). pii: E3995. doi: 10.3390/molecules24213995. 3.06 (4)

69- Shagufta Perveen*, Jawaher Alqahtani, Raha Orfali , Areej Mohammad Al- Taweel, Hasan Soliman Yusufoglu, Maged Saad Abdel-Kader, Orazio Taglialatela-Scafati, Antimicrobial guaianolide sesquiterpenoids from leaves of the Saudi Arabian plant Anvillea garcinii, Fitoterapia 134, 129-134, 2019. 2.431 (1)

68- Raha Orfali, Shagufta Perveen*, Secondary metabolites from the Aspergillus sp. in the rhizosphere soil of Phoenix dactylifera (Palm tree), BMC Chemistry (2019) 13:103 (Formerly Chemistry Central Journal). 1.77 (1)

67- Raha Orfali, Shagufta Perveen*, Nasir Siddiqui, Perwez Alam, Tawfeq Alhowiriny, Areej Al-Taweel, Sami Al-Yahya, Najwa Mejrashi, Rashad Mehmood, Shabana I. Khan. Quantitative and biological analysis of active extract of the leaves of Plicosepalus curviflorus by validated HPTLC method, Journal of Analytical Methods in Chemistry, 2019 Volume 2019, Article ID 7435909, pp. 1-8. 1.589 (1) 6

66- Raha Orfali, Shagufta Perveen*, New Bioactive Metabolites from the Thermophilic Fungus Penicillium sp. Isolated from Ghamiqa Hot Spring in Saudi Arabia, Journal of Chemistry, 2019, Volume 2019, Article ID 7162948, 1-7. 1.727 (1)

65- Rabia Hameed, Afsar Khan, Sehroon Khan, Shagufta Perveen, Computational Approaches towards Kinases as Attractive Targets for Anticancer Drug Discovery and Development. Anticancer Agents in Medicinal Chemistry. 2019, 19 (5):592-598. 2.556 (4)

64- Shagufta Perveen*, Raha Orfali, Areej Mohammad Al-Taweel, Afsar Khan, Bandar Alghanem, Hayat Shaibah. Simultaneous identification of phenolic and flavonoid contents in bee pollen by HPLC-ESI-MS data, Biomedical Research 2019; 30 (5) (1). 2018

63- Muhammad Aamir, Asma Sadaf, Sehroon Khan, Shagufta Perveen, Afsar Khan, Recent Advancement in the Diagnosis and Treatment of Leprosy, Current Topics in Medicinal Chemistry, Volume 18, Issue 18, 2018, 1550-1558. 3.442 (4)

62- Raha Orfali, Nasir Siddiqui, Perwez Alam, Tawfeq Alhowiriny, Areej Al-Taweel, Sami Al-Yahya, Najwa Mejrashi, Rsshad Mehmood, Shabana I. Khan, and Shagufta Perveen*.

61- Quantitative and biological analysis of iridoid glycoside & ursolic acid in aerial parts of Nepeta deflersiana by validated HPTLC method, Evidence-Based Complementary and Alternative Medicine, Volume 2018, Article ID 8790769, 11 pages. 2.064 (4)

60- Shagufta Perveen*, Areej Mohammad Al-Taweel, Hasan Soliman Yusufoglu, Ghada Ahmed Fawzy, Ahmed Foudah, Maged Saad Abdel-Kader, Hepatoprotective and cytotoxic activities of Anvillea garcinii and isolation of four new secondary metabolites, Journal of Natural Medicine. 2018, 72:106-117. 1.966 (1)

59- Nourah Al-Zoman, Iman, Areej Al-Taweel, Ghada Fawzy, Shagufta Perveen, Rasool Tareen, Ruba Sabbagh, CE-DAD Determination of Scutellarein and Caffeic Acid in Abelia triflora crude extract, Journal of Chromatographic Science, 2018, Vol. 56, No. 8, 746–752. 1.216 (3)7

Current profession

Current professional activities type: 


Royal Society of Chemistry
Prizes, Grants and Awards

Other Awards

Apr 2020
Fellowship awarded by Royal Society of Chemistry of United Kingdom.
Jul 2006
Scholarship International Research Support Program
Scholarship awarded by Higher Education Commission of Pakistan in 2006 to 2007
Jan 2003
Scholarship Indigenous 5000 PhD Fellowship
Scholarship awarded by HEC Pakistan in 2003-2008

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