Uzma Salar

M. Ali, S. Shamim, U. Salar, P. Taslimi, S. M. Saad, T. Taskin-Tok, M. Taha, K. M. Khan, 2-Amino-6-ethoxy-4-arylpyridine-3,5-dicarbonitrile scaffolds as potential acetylcholinesterase and butyrylcholinesterase inhibitors. Journal of Molecular Structure, 2025, 1321, 139863.

F. Naz, F. Seraj, M. Taha, M. Özil, U. Salar, N. Baltaş, Z. Ul-Haq, S. S. Tariq, K. M. Khan, Diversely functionalized benzopyran scaffolds as potential lead candidates for treating Alzheimer's disease and diabetes. Journal of Molecular Structure, 2025, 1322, 140317.

Y. Khan, M. Solangi, K. M. Khan, N. Ullah, J. Iqbal, Z. Hussain, I. A. Khan, U. Salar, M. Taha, Exploration of thiazine Schiff bases as promising urease inhibitors: Design, synthesis, enzyme inhibition, kinetic analysis, ADME/T evaluation, and molecular docking studies. International Journal of Biological Macromolecules, 2024, 281, 136361.

U. Salar, Atia-tul-Wahab, M. I. Choudhary, Biochemical Evaluation and Ligand Binding Studies on Glycerophosphodiester Phosphodiesterase from Staphylococcus aureus using STD-NMR Spectroscopy and Molecular Docking Analysis. Bioorganic Chemistry, 2024, 144, 107153.

Atia-tul-Wahab, F. Nadeem, U. Salar, H. M. Bilal, M. Farooqui, S. Javaid, S. Sadaf, Coumarin derivatives as new anti-biofilm agents against Staphylococcus aureus. PloS one, 2024, 19 (9), e0307439.

M. Maqbool, M. Solangi, K. M. Khan, M. Özil, N. Baltaş, U. Salar, S. S. Tariq, Z. Ul Haq, M. Taha, Imidazole‐thiadiazole hybrids: A multitarget de novo drug design approach, in vitro evaluation, ADME/T, and in silico studies. Archiv der Pharmazie, 2024, e2400325.

Alishba, I. Ali, S. Hameed, K. M. Khan, U. Salar, M. Taha, N. Sadeghian, P. Taslimi, B. Tuzun, D. Özerkan, H. Dedeakayogullari, E. Ulukaya, Exploring benzo[b][1,4]thiazine derivatives: Multitarget inhibition, structure–activity relationship, molecular docking, and ADMET analysis. ChemistrySelect, 2024, 9, e202404087.

M. Khan, M. U. Rehman, A. Alam, M. Ashraf, U. Salar, K. M. Khan, A. F. AlAsmari, F. Alasmari, Exploring the DPPH radical scavenging potential in 5-arylidene-N,N-diethylthiobarbiturates. Russian Journal of Bioorganic Chemistry, 2024, 50, 1928-1934.

M. Khan, G. Ahad, A. Alam, S. Ullah, A. Khan, Kanwal, U. Salar, A. Wadood, A. Ajmal, K. M. Khan, S. Perveen, J. Uddin, A. Al-Harrasi, Synthesis of new bis(dimethylamino)benzophenone hydrazone for diabetic management: In-vitro and in-silico approach. Heliyon, 2024, 10(1), e23323

Alishba, U. Ahmed, M. Taha, N. A. Khan, U. Salar, K. M. Khan, A. Anwar, R. Siddiqui, Potential anti-amoebic effects of synthetic 1,4-benzothiazine derivatives against Acanthamoeba castellanii. Heliyon, 2024, 10(1), e23258.

S. Hameed, F. Saleem, M. Özil, N. Baltaş, U. Salar, S. Ashraf, Z. Ul-Haq, M. Taha, K. M. Khan, Indenoquinoxaline-phenylacrylohydrazide hybrids as promising drug candidates for the treatment of type 2 diabetes: In vitro and in silico evaluation of enzyme inhibition and antioxidant activity. International Journal of Biological Macromolecules, 2024, 129517.

M. Khan, N. Ambreen, F. Saleem, M. A. Lodhi, F. Jan, M. Kamal, U. Salar, M. Taha, K. M. Khan, Nicotinonitriles as potential inhibitors of α-glucosidase, tyrosinase, and urease enzymes: Synthesis, characterization, in vitro, and in silico studies. Journal of Molecular Structure, 2024, 1305, 137742.

S. A. Egu, I. Ali, K. M. Khan, S. Chigurupati, U. Qureshi, U. Salar, Z. Ul-Haq, S. A Almahmoud, S. G. Felemban, M. Ali, M. Taha, Rhodanine-benzamides as potential hits for α-amylase enzyme inhibitors and radical (DPPH and ABTS) scavengers. Molecular Diversity, 2024 https://doi.org/10.1007/s11030-024-10813-z.

M. Manzoor, M. Solangi, S. Perveen, U. Salar, F. Naz, J. Iqbal, Z. Hussain, A. Imran, M. Taha, K. M. Khan, Exploring tricycle acridines as prospective urease inhibitors: synthesis via microwave assistance, in vitro evaluation, kinetic profiling, and molecular docking investigations. Journal of the Iranian Chemical Society, 2024, 21 (4), 1163-1183.

N A Siregar, M I Choudhary, A T Wahab, U Salar, and E Munir, Urease from Vigna umbellata seeds: isolation, partial purification, characterization and antifungal activity. IOP Conf. Series: Earth and Environmental Science, 2024, 1302, 012091. (Conference Paper)

F. Saleem, M. Haider, K.M. Khan, M. Özil, N. Baltaş, Z. Ul-Haq, U. Qureshi, U. Salar, M. Taha, S. Hameed, N. Ullah, Regioselective syntheses of 2-oxopyridine carbonitrile derivatives and evaluation for antihyperglycemic and antioxidant potential. International Journal of Biological Macromolecules, 2023, 241, 124589.

M. Solangi, K.M. Khan, X. Ji, M. Özil, N. Baltaş, U. Salar, A. Khan, Z. Ul Haq, H. Meghwar, M. Taha, Indole-pyridine carbonitriles: multicomponent reaction synthesis and bio-evaluation as potential hits against diabetes mellitus. Future Medicinal Chemistry, 2023, 5(21), 1943-1965.

M. Khan, A. Alam, U. Salar, S. Chigurupati , F. Saleem, S. Hameed, M. Taha , and K. M. Khan, Flurbiprofen derivatives as potential DPPH and ABTS radical scavengers. Russian Journal of Organic Chemistry, 2023, 59(9), 1577-1582.

S. Hameed, Kanwal, U. Salar, M. Lateef, A. Wadood, M. Taha, A. Ur. Rehman, K. M. Khan, 1,2,3-Benzotriazoles as potential leads for gastric and peptic ulcer management: in vitro urease inhibitory activity and molecular docking study. Russian Journal of Organic Chemistry, 2023, 59(9), 1563-1576.

F. Seraj, K. M. Khan, J. Iqbal, A. Imran, Z. Hussain, U. Salar, S. Hameed, M. Taha, Evaluation of synthetic aminoquinoline derivatives as urease inhibitors: in vitro, in silico and kinetic studies. Future Medicinal Chemistry, 2023, 15(18), 1703-1717.

M. Hamid, U. Salar, Y. Rashid, M.K. Azim, M. Khalid, S. Naz, T. Aziz, M. Alharbi, A. Alshammari, A.F. Alasmari, Determining the 3-substituted Coumarins inhibitory potential against the HslV protease of E. coli. European Review for Medical and Pharmacological Sciences, 2023, 27, 9169-9182.

B. Fatima, F. Saleem, U. Salar, S. Chigurupati, S. G. Felemban, Z. Ul-Haq, S. S. Tariq, S. A. Almahmoud, M. Taha, S. T. A. Shah, K. M. Khan, Multitargeted inhibition of key enzymes associated with diabetes and alzheimer's disease by 1,3,4-oxadiazole derivatives: synthesis, in vitro screening, and computational studies. Archiv der Pharmazie, 2023, e2300384.

S. Shamim, K. M. Khan M. Ali, M. Mahdavi, U. Salar, M. Mohammadi-Khanaposhtani, M. A. Faramarzi, N. Ullah, M. Taha, Diphenyl substituted triazine derivatives: synthesis, α-glucosidase inhibitory activity, kinetics, and in silico studies. Future Medicinal Chemistry, 2023, 15(18), 1651-1668.

F. Saleem, F. Shamim, M. Özil, N. Baltaş, U. Salar, S. Ashraf, Z. Ul-Haq, M. Taha, M. Solangi, K. M. Khan, Multicomponent diastereoselective synthesis of tetrahydropyridines as α-amylase and α-glucosidase enzymes inhibitors. Future Medicinal Chemistry, 2023, 15(15), 1343-1368.

I.U. Haq, I. Ali, U. Salar, S. Chigurupati, U. Qureshi, S.A. Almahmoud, S. Hameed, S. Konanki, M. Ahmad, M. Ali, Z.U. Haq, Synthetic piperidine-substituted chalcones as potential hits for α-amylase inhibitory and antioxidant activities. Future Medicinal Chemistry, 2023, 15 (6), 497 – 515.

I. G. Asuquo, M. Solangi, K. M. Khan, S. Chigurupati, I. E. Otuokere, F. K. Ekuma, U. Salar, S. G. Felemban, A. U. Rehman, A. Wadood, M. Taha, Design, synthesis and bio-evaluation of indolin-2-ones as potential antidiabetic agents. Future Medicinal Chemistry, 2023, 15(1), 25-42.

I. U. Haq, I. Ali, K. M. Khan, S. Chigurupati, A. Habib, U. Salar, M. Ahmad, M. Aldubayan, S. G. Felemban, M. Taha, Z. U. Haq, New Arylidene linked Chromane-2,4-dione Analogs: Syntheses and Evaluation as α-Amylase Inhibitors and Radical Scavengers. Chemical Papers, 2023, 77(5), 2581–2604.

I. Ali, R. Rafique, K. M. Khan, S. Chigurupati, X. Ji, A. Wadood, U. Salar, S. A. Almahmoud, A. U. Rehman, S. G. Felemban, S. Hameed, S. Perveen, Synthetic Benzofuran-linked Chalcones with Dual Actions: A Potential Therapeutic Approach to Manage Diabetes Mellitus. Future Medicinal Chemistry, 2023, 15(2), 167-187.

M. Khan, M. Raheel, S. Shah, M. Ibrahim, M. Asif, U. Salar, K. M. Khan, Synthesis, Characterization, DPPH, Ferric Reducing and Ferrous Ion-Chelating Activities of Isophthalate Schiff Bases. Letters in Drug Design & Discovery, 2023, 20, 31-39.

Z. Shaikh, U. Ashiq, R. A. Jamal, S. Gul, M. M. Tahir, S. Sultan, U. Salar, K. M. Khan, Synthesis, Characterization, Lipoxygenase, and Tyrosinase Inhibitory Activities of Non-Cytotoxic Titanium(III) and (IV) Hydrazide Complexes. Bulletin of the Chemical Society of Ethiopia, 2023, 37(2), 315-333.

F. Saleem, K. M. Khan, N. Ullah, M. Özil, N. Baltaş, S. Hameed, U. Salar, A. Wadood, A. U. Rehman, M. Kumar, M. Taha, S. M. Haider, Bioevaluation of Synthetic Pyridones as Dual Inhibitors of α-Amylase and α-Glucosidase Enzymes and Potential Antioxidants. Archiv der Pharmazie, 2023, 356, e2200400.

A. Ata, K. M. Khan, M. Lateef, U. Salar, A. Anwar, A. Wadood, A. U. Rehman, S. Hameed, F. Zafar, M. Taha, S. Perveen, Evaluation of S-Substituted-2-mercaptobenzimidazole Analogs for Urease Inhibitory and DPPH Radical Scavenging Potential: Synthesis, Bioactivity, and Molecular Docking Study. Journal of the Iranian Chemical Society, 2023, 20:175-191.

A. Ata, U. Salar, F. Saleem, M. Lateef, S. A. Khan, K. M. Khan, M. Taha, S. M. Haider, Z. Ul-Haq, Identification of Potential Urease Inhibitors and Antioxidants based on Saccharin Derived Analogs: Synthesis, In Vitro, and In Silico Studies. Journal of Molecular Structure, 2023, 134376.

S. A. Egu, I. Ali, K. M. Khan, S. Chigurupati, U. Qureshi, U. Salar, M. Taha, S. G. Felemban, V. Venugopal, Z. Ul-Haq, Syntheses, in vitro, and in silico studies of rhodanine based Schiff bases as potential α-amylase inhibitors and radicals (DPPH and ABTS) scavengers. Molecular Diversity, 2023, 27(2), 767-791.

U. Salar, A. T. Wahab, M. I. Choudhary, Functional and ligand binding studies of NAD(P)H hydrate dehydratase enzyme from vancomycin-resistant Staphylococcus aureus by NMR spectroscopic approach, including saturation transfer difference (STD-NMR) spectroscopy. Biochimie, 2022, 201, 148-156.

S. Hameed, K. M. Khan, U. Salar, M. Özil, N. Baltaş, F. Saleem, U. Qureshi, M. Taha, Z. Ul-Haq, Hydrazinyl Thiazole linked Indenoquinoxalin Hybrids: Potential Leads to Treat Hyperglycemia and Oxidative Stress; Multistep Synthesis, α-Amylase, α-Glucosidase Inhibitory and Antioxidant Activities. International Journal of Biological Macromolecules, 2022, 221, 1294-1312.

S. Hameed, O. Babatunde, U. Salar, A. Jabbar, S. Chigurupati, M. Solangi, L. Atta, Z. U. Haq, F. Saleem, S. Bhatia, A. A. Harrasi, M. Taha, K. M. Khan, Efficient one-pot synthesis of arylated pyrazole-fused pyran analogs: As leads to treating diabetes and Alzheimer's disease. Future Medicinal Chemistry, 2022, 14(21), 1507-1526.

M. Hamid, S. Aurangzeb, Y. Rashid, S. Shamim, U. Salar, M.K. Azim, K.M. Khan, S. Bashir, Inhibitory potential of triazines and hydrazinyl thiazole substituted chromones against the HslVU protease/chaperone complex, a novel drug target. European Review for Medical and Pharmacological Sciences, 2022, 26 (22): 8567-8575.

S. Hameed, K. M. Khan, P. Taslimi, U. Salar, T. Taskin-Tok, D. Kisa, F. Saleem, M. Solangi, M. H. U. Ahmed, K. Rani, Evaluation of synthetic 2-aryl quinoxaline derivatives as α-amylase, α-glucosidase, acetylcholinesterase, and butyrylcholinesterase inhibitors. International Journal of Biological Macromolecules, 2022, 211, 653-668.

M. M. Balogun, S. Shamim, K. M. Khan, M. Mahdavi, U. Salar, I. A. Oladosu, M. M. Khanaposhtani, M. A. Faramarzi, D. O. Moronkola, M. Taha, F. Rahim, S. Perveen, Synthesis and Evaluation of 6-Ethoxy-2-mercaptobenzothiazole Scaffolds as Potential α-Glucosidase Inhibitors. ChemistrySelect, 2022, 7 (26), e202200855.

U. Kulsoom, U. Salar, K. M. Khan, S. Chigurupati, S. Syed, A. Wadood, A. U. Rehman, B. Fatima, F. Saleem, M. Taha, S. G. Felemban, S. R. Dachani, S. Perveen, Synthesis and Evaluation of Aryl Aminomethylene Substituted Barbiturates and Thiobarbiturates as Novel α-Amylase Inhibitors and Radical Scavengers. Monatshefte für Chemie-Chemical Monthly, 2022, 153, 949-960.

H. N. Malik, A. Jabeen, S. Ashraf, Z. Ul Haq, U. Salar, Arshia, K. M. Khan, Benzophenone and coumarin derivatives as 3-CLPro inhibitors: Targeting cytokine storm through in silico and in vitro approaches. Journal of Molecular Structure, 2022, 1265, 133478.

I. Ali, R. Rafique, K. M. Khan, S. Chigurupati, X. Ji, A. Wadood, A. U. Rehman, U. Salar, N. M. Alyamani, S. Hameed, M. Taha, S. Hussain, S. Perveen, Benzofuran Hybrids as Cholinesterase (AChE and BChE) Inhibitors: In Vitro, In Silico, and Kinetic Studies. Russian Journal of Bioorganic Chemistry, 2022, ISSN 1068-1620.

S. Aurangzeb, M. Hamid, U. Salar, Y. Rashid, K. M. Khan, M. K. Azim, S. Bashir, 3-substituted coumarin derivatives over-activate the HslV protease: A potential drug target for antibacterial activity. Pakistan Journal of Pharmaceutical Sciences, 2022, 35(4), 1241 – 1250.

M. A. Ansari, S. M. Saad, K. M. Khan, U. Salar, P. Taslimi, T. Taskın‐Tok, F. Saleem, S. Jahangir, Biology‐oriented drug synthesis and evaluation of secnidazole esters as novel enzyme ınhibitors. Archiv der Pharmazie, 2022, 355(2), 2100376.
U. Salar, B. Qureshi, K. M. Khan, M. A. Lodhi, Z. Ul Haq, F. A. Khan, F. Naz, M. Taha, S. Perveen, S. Hussain, Aryl hydrazones linked thiazolyl coumarin hybrids as potential urease inhibitors. Journal of the Iranian Chemical Society, 2022, 19:1221-1238.

O. Babatunde, S. Hameed, U. Salar, S. Chigurupati, A. Wadood, A. U. Rehman, V. Venugopal, K. M. Khan, M. Taha, S. Perveen, Dihydroquinazolin-4 (1H)-one derivatives as novel and potential leads for diabetic management. Molecular Diversity, 2022, 26, 849-868.

S. Shah, M. Raheel, M. Khan, M. Ali, A. Wadood, A.U. Rehman, Z. Shah, U. Salar, K. M. Khan, Bis-1,3,4-oxadiazole derivatives as novel and potential urease inhibitors; Synthesis, in vitro, and in silico studies. Medicinal Chemistry, 2022, 18(7), 820-830.

A. A. Akande, U. Salar, K. M. Khan, S. Syed, S. A. Aboaba, S. Chigurupati, A. Wadood, M. Riaz, M. Taha, S. Bhatia, Kanwal, S. Shamim, S. Perveen, Substituted Benzimidazole Analogues as Potential α-Amylase Inhibitors and Radical Scavengers. ACS Omega, 2021, 6, 22726-22739.

M. M. Balogun, S. Shamim, K. M. Khan, U. Salar, I. A. Oladosu, M. Lateef, A. Wadood, M. Taha, D. O. Moronkola, A. U. Rehman, F. Rahim, S. Perveen, 2-Mercapto Benzoxazole Derivatives as Novel Leads: Urease Inhibition, In Vitro and In Silico Studies. ChemistrySelect, 2021, 6 (33), 8490-8498.

F. Ali, S. Shamim, M. Lateef, K. M. Khan, M. Taha, U. Salar, A. Wadood, A. U. Rehman, N. U. A. Nawaz, S. Perveen, N-Aryl-3,4-dihydroisoquinoline Carbothioamide Analogues as Potential Urease Inhibitors. ACS Omega, 2021, 6, 15794-15803.

Bushra, S. Shamim, K. M. Khan, N. Ullah, M. Mahdavi, M. A. Faramarzi, B. Larijani, U. Salar, R. Rafique, M. Taha, S. Perveen, Synthesis, In Vitro, and In Silico Evaluation of Indazole Schiff Bases as Potential α-Glucosidase Inhibitors. Journal of Molecular Structure, 2021, 1242, 130826.

H. A. Younus, M. al-Rashida, A. Hameed, M. Uroos, U. Salar, S. Rana, K. M. Khan, Multicomponent reactions (MCR) in medicinal chemistry: a patent review (2010-2020). Expert Opinion on Therapeutic Patents, 2021, 31(3), 267-289.

H. Wali, A. Anwar, S. Shamim, K. M. Khan, M. Mahdavi, U. Salar, B. Larijani, S. Perveen, M. Taha, M. A. Faramarzi, Synthesis, in vitro, and in silico studies of newly functionalized quinazolinone analogs for the identification of potent α-glucosidase inhibitors. Journal of the Iranian Chemical Society, 2021, 18 (8), 2017-2034.

A. T. Bale, U. Salar, K. M. Khan, S. Chigurupati, T. Fasina, F. Ali, M. Ali, S. S. Nanda, M. Taha, S. Perveen, Chalcones and bis-chalcones analogs as DPPH and ABTS radical scavengers. Letters in Drug Design & Discovery, 2021, 18 (3), 1-9.

F. Seraj, K.M. Khan, A. Khan, M. Ali, R. Khalil, Z. Ul-Haq, S. Hameed, M. Taha, U. Salar, S. Perveen, Biology-oriented drug synthesis (BIODS), in vitro urease inhibitory activity, and in silico studies on ibuprofen derivatives. Molecular Diversity, 2021, 25 (1), 143-157.

I. Ali, R. Rafique, K. M. Khan, S. Chigurupati, X. Ji, A. Wadood, A. U. Rehman, U. Salar, M. S. Iqbal, M. Taha, S. Perveen, B. Ali, Potent α-amylase inhibitors and radical (DPPH and ABTS) scavengers based on benzofuran-2-yl(phenyl)methanone derivatives: Syntheses, in vitro, kinetics, and in silico studies. Bioorganic Chemistry, 2020, 104, 104238.

F. Naz, Kanwal, M. Latif, U. Salar, K. M. Khan, M. al-Rashid, I. Ali, B. Ali, M. Taha, S. Perveen, 4-Oxycoumarinyl Linked Acetohydrazide Schiff bases as Potent Urease Inhibitors. Bioorganic Chemistry, 2020, 105, 104365.

S. Shamim, K. M. Khan, N. Ullah, S. Chigurupati, A. Wadood, A. U. Rehman, M. Ali, U. Salar, A. Alhowail, M. Taha, S. Perveen, Synthesis and screening of (E)-3-(2-benzylidenehydrazinyl)-5,6-diphenyl-1,2,4-triazine analogs as novel dual inhibitors of α-amylase and α-glucosidase. Bioorganic Chemistry, 2020, 101, 103979.

M. Ali, K. M. Khan, M. Mahdavi, A. Jabbar, S. Shamim, U. Salar, M. Taha, S. Parveen, B. Larijani, M. A. Faramarzi, Synthesis, In vitro and In silico screening of 2-amino-4-aryl-6-(phenylthio) pyridine-3, 5-dicarbonitriles as novel α-glucosidase inhibitors. Bioorganic Chemistry, 2020, 100, 103879.

R. Rafique, Arshia, Kanwal, K. M. Khan, S. Chigurupati, U. Salar, M. Taha, S. Perveen, Discovery of new N-hydrazinecarbothioamide indazole hybrids: As potential radical (ABTS and DPPH) scavengers. Letters in Drug Design & Discovery, 2020, 17, 1177-1185.

U. Salar, K. M. Khan, A. Jabeen, S. Hussain, A. Faheem, F. Naqvi, S. Perveen, Diversified Thiazole Substituted Coumarins and Chromones; As Non Cytotoxic ROS and NO Inhibitors. Letters in Drug Design & Discovery, 2020, 17 (5), 545-553.
M. Khan, G. Ahad, A. Khan, S. Shah, Kanwal, U. Salar, S. M. Salman, K. M. Khan, Antiglycation Activity of N,N-Diethylthiobarbiturates Derivatives. Letters in Drug Design & Discovery, 2020, 17 (4), 409-515.

S. Wahid, S. Jahangir, M. A. Versiani, K. M. Khan, U. Salar, M. Ashraf, U. Farzand, A. Wadood, M. Taha, S. Perveen, Atenolol Thiourea Hybrid as Potent Urease Inhibitors: Design, Biology-Oriented Drug Synthesis, Inhibitory Activity Screening, and Molecular Docking Studies. Bioorganic Chemistry, 2020, 94, 103359.

R. Rafique, K. M. Khan, Arshia, S. Chigurupati, A. Wadood, A. U. Rehman, U. Salar, V. Venugopal, S. Shamim, M. Taha, S. Perveen, Synthesis, In vitro α-Amylase Inhibitory, and Radicals (DPPH & ABTS) Scavenging Potentials of New N-Sulfonohydrazide Substituted Indazoles. Bioorganic Chemistry, 2020, 94, 103410.

Z. Arshad, S. Saied, B. Ali, U. Salar, S. Tauseef, Arshia, M. Ajaz, U. Khan, S. M. Haider, M. Taha, K. M. Khan, Synthesis of N'-Nicotinoyl Sulfonohydrazides and their Antimicrobial Activity. Journal of The Chemical Society of Pakistan, 2020, 42, 597-604.

M. Khan, M. U. Rehman, N. Qadir, M. Ashraf, T. Ismail, M. Ismail, Kanwal, U. Salar, K. M. Khan, S. Perveen, Acetylcholinesterase and Butyrylcholinesterase Inhibitory Activities of 5-Arylidene-N, N-Diethylthiobarbiturates. Journal of The Chemical Society of Pakistan, 2020, 42 (1), 134-140.

U. Salar, K. M. Khan, A. Jabeen, A. Faheem, F. Naqvi, S. Ahmed, E. Iqbal, F. Ali, Kanwal, S. Perveen, ROS Inhibitory Activity and Cytotoxicity Evaluation of Benzoyl, Acetyl, Alkyl Ester, and Sulfonate Ester Substituted Coumarin Derivatives. Medicinal Chemistry, 2020, 16, 1-13.

S. Ullah, S. Mirza, U. Salar, S. Hussain, K. Javaid, K. M. Khan, R. Khalil, Atia-tul-Wahab, Zaheer Ul-Haq, S. Perveen, M. I. Choudhary, 2-Mercapto Benzothiazole Derivatives: As Potential Leads for the Diabetic Management. Medicinal Chemistry, 2020, 16 (6), 826-840.

U. Salar, A. Nizamani, F. Arshad, K. M. Khan, M. I. Fakhri, S. Perveen, N. Ahmed, M. I. Choudhary, Bis-coumarins; Non-Cytotoxic Selective Urease Inhibitors and Antiglycation Agents. Bioorganic Chemistry, 2019, 91, 103170.

S. Hameed, Kanwal, F. Seraj, R. Rafique, S. Chigurupati, A. Wadood, Ashfaq Ur Rehman, V. Venugopal, U. Salar, M. Taha, K. M. Khan, Synthesis of benzotriazoles derivatives and their dual potential as α-amylase and α-glucosidase inhibitors in vitro: Structure-activity relationship, molecular docking, and kinetic studies. European Journal of Medicinal Chemistry, 2019, 183, 111677.

G. Mohiuddin, K. M. Khan, U. Salar, Kanwal, M. A. Lodhi, F. Begum, S. Perveen, Tyrosinase Inhibitory Activity of S-Naproxen Derivatives. Letters in Drug Design & Discovery, 2019, 16 (11), 1276-1285.

M. Khan, S. Khan, U. Salar, K. M. Khan, G. Rehman, N. Gul, I. Khan, Biology-oriented drug synthesis (BIODS), structural characterization and bioactivities of novel albendazole derivatives. Letters in Drug Design & Discovery, 2019, 16 (12), 1329-1338.

M. Khan, G. Ahad, A. Manaf, R. Naz, S. R. Hussain, F. Deeba, S. Shah, A. Khan, M. Ali, K. Zaman, S. Zafar, U. Salar, A. Hameed, K. M. Khan, Synthesis, in vitro urease inhibitory activity, and molecular docking studies of (perfluorophenyl)hydrazone derivatives. Medicinal Chemistry Research, 2019, 28 (6), 873-883.

U. Salar, K. M. Khan, S. Chigurupati, S. Syed, S. Vijayabalan, A. Wadood, M. Riaz, M. Ghufran, S. Perveen, New hybrid scaffolds based on hydrazinyl thiazole substituted coumarin; As novel leads of dual potential; in vitro α-amylase inhibitory and antioxidant (DPPH and ABTS radical scavenging) activities. Medicinal Chemistry, 2019, 15, 87-101.

Kanwal, K. M. Khan, U. Salar, S. Afzal, A. Wadood, M. Taha, S. Perveen, H. Khan, J. Lecka, J. Sévigny, J. Iqbal, Schiff bases of tryptamine as potent inhibitors of nucleoside triphosphate diphosphohydrolases (NTPDase): Structure-activity relationship. Bioorganic Chemistry, 2019, 82, 253-266.

G. Mohiuddin, K. M. Khan, U. Salar, Kanwal, M. A. Lodhi, A. Wadood, M. Riaz, S. Perveen, Biology-oriented drug synthesis (BIODS), in vitro urease inhibitory activity, and in silico study of S-naproxen derivatives. Bioorganic Chemistry, 2019, 83, 29-46.

U. Salar, K. M. Khan, S. A. Ejaz, A. Hameed, M. al-Rashida, S. Perveen, M. N. Tahir, J. Iqbal, M. Taha, Coumarinyl aryl/alkyl sulfonates with dual potential: Alkaline phosphatase and ROS inhibitory activities; In silico molecular modeling and ADME evaluation. Letters in Drug Design & Discovery, 2019, 6, 256-272.

M. Khan, R. Ahmad, G. Rehman, N. Gul, S. Shah, U. Salar, S. Perveen, K. M. Khan, Synthesis of pyridinyl-benzo[d]imidazole/pyridinyl-benzo[d]thiazole derivatives and their yeast glucose uptake activity In vitro. Letters in Drug Design & Discovery, 2019, 16, 984-993.

A. A. Adegboye, K. M. Khan, U. Salar, S. A. Aboaba, Kanwal, S. Chigurupati, I. Fatima, M. Taha, A. Wadood, J. I. Mohammad, H. Khan, S. Perveen, 2-Aryl benzimidazoles: Synthesis, in vitro α-amylase inhibitory activity, and molecular docking study. European Journal of Medicinal Chemistry, 2018, 150, 248-260.

A. T. Bale, K. M. Khan, U. Salar, S. Chigurupati, T. Fasina, F. Ali, Kanwal, A. Wadood, M. Taha, S. S. Nanda, M. Ghufran, S. Perveen, Chalcones and bis-chalcones: As potential α-amylase inhibitors; Synthesis, in vitro screening, and molecular modelling studies. Bioorganic Chemistry, 2018, 79, 179-189.

S. Yousuf, K. M. Khan, U. Salar, S. Chigurupati, M. T. Muhammad, A. Wadood, M. Aldubayan, V. Vijayan, M. Riaz, S. Perveen, 2ʹ-Aryl and 4ʹ-Arylidene Substituted Pyrazolones: As Potential α-Amylase Inhibitors. European Journal of Medicinal Chemistry, 2018, 159, 47-58.

B. Ali, K. M. Khan, U. Salar, Kanwal, S. Hussain, M. Ashraf, M. Riaz, A. Wadood, M. Taha, S. Perveen, 1-[(4′-Chlorophenyl) carbonyl-4-(aryl) thiosemicarbazide derivatives as potent urease inhibitors: Synthesis, in vitro and in silico studies. Bioorganic Chemistry, 2018, 79, 363-371.

M. Ali, K. M. Khan, U. Salar, M. Ashraf, M. Taha, A. Wadood, S. Hamid, M. Riaz, B. Ali, S. Shamim, F. Ali, S. Perveen, Synthesis, in vitro α-glucosidase inhibitory activity, and in silico study of (E)-thiosemicarbazones and (E)-2-(2-(arylmethylene)hydrazinyl)-4-arylthiazole derivatives. Molecular Diversity, 2018, 22(4), 841-61.

B. Bano, Kanwal, K. M. Khan, F. Begum, A. Lodhi, U. Salar, R. Khalil, Zaheer-Ul-Haq, S. Perveen, Benzylidine indane-1,3-diones: As Novel Urease Inhibitors; Synthesis, In vitro, and In silico Studies. Bioorganic Chemistry, 2018, 81, 658-671.

B. Bano, Kanwal, K. M. Khan, A. Lodhi, U. Salar, F. Begum, M. Ali, M. Taha, S. Perveen, Synthesis, in vitro urease inhibitory activity, and molecular docking studies of thiourea and urea derivatives. Bioorganic Chemistry, 2018, 80, 129-144.

M. Khan, A. Alam, K. M. Khan, U. Salar, S. Chigurupati, A. Wadood, F. Ali, J. I. Mohammad, M. Riaz, S. Perveen, Flurbiprofen derivatives as novel α-amylase inhibitors: Biology-oriented drug synthesis (BIODS), In vitro, and In silico evaluation. Bioorganic Chemistry, 2018, 81, 157-167.

M. Nazir, M. A. Abbasi, Aziz-ur-Rehman, S. Z. Siddiqui, K. M. Khan, Kanwal, U. Salar, M. Shahid, M. Ashraf, M. A. Lodhi, F. A. Khan, New indole based hybrid oxadiazole scaffolds with N-substituted acetamides: As potent anti-diabetic agents. Bioorganic Chemistry, 2018, 81, 253-263.

U. Salar, K. M. Khan, H. Muhammad, M. I. Fakhri, Sanaullah, S. Perveen, M. I. Choudhary, Anti-MRSA (Multidrug resistant Staphylococcus aureus) activity of 3-substituted coumarins. Letters in Drug Design & Discovery, 2018, 15(4), 353-362.
U. Salar, K. M. Khan, M. I. Fakhri, S. Hussain, S. Tauseef, S. Ameer, A. Wadood, H. Khan, S. Perveen, 1,1ꞌ-Carbonyldiimidazole (CDI) mediated facile synthesis, structural characterization, antimicrobial activity and in-silico studies of coumarin-3-carboxamide derivatives. Medicinal Chemistry, 2018, 14, 86-101.

S. Shamim, K. M. Khan, U. Salar, F. Ali, M. A. Lodhi, M. Taha, F. A. Khan, S. Ashraf, Zaheer-Ul-Haq, M. Ali, S. Perveen, 5-Acetyl-6-methyl-4-aryl-3,4-dihydropyrimidin-2(1H)-ones: As potent urease inhibitors; synthesis, in vitro screening, and molecular modeling study. Bioorganic Chemistry, 2018, 76, 37-52.

A. Yasir, S. Ishtiaq, M. Jahangir, M. Ajaib, U. Salar, K. M. Khan, Biology-oriented synthesis (BIOS) of piperine derivatives and their comparative analgesic and antiinflammatory activities. Medicinal Chemistry, 2018, 14, 269-280.

S. Yousuf, K. M. Khan, U. Salar, A. Jabeen, S. Ahmed, M. T. Muhammad, A. Faheem, S. Perveen, New bis-pyrazolones as potential leads for ROS inhibition; environment friendly green synthesis, structural characterization, and in vitro studies. Medicinal Chemistry, 2018, 14, 536-548.

M. Hayat, K. M. Khan, S. Saeed, U. Salar, M. Khan, T. Baig, A. Ahmad, S. Parveen, M. Taha, Antimicrobial activities of synthetic arylidine nicotinic and isonicotinic hydrazones. Letters in Drug Design & Discovery, 2018, 15(10), 1057-1067.
G. Ahad, M. Khan, A. Khan, M. Ibrahim, U. Salar, Kanwal, K. M. Khan, S. Perveen, Synthesis, structural characterization, and antioxidant activities of 2,4-dinitrophenyl-hydrazone derivatives. Journal of the Chemical Society of Pakistan, 2018, 40, 961-973.

U. Salar, K. M. Khan, S. Chigurupati, M. Taha, A. Wadood, S. Vijayabalan, M. Ghufran, S. Perveen, New hybrid hydrazinyl thiazole substituted chromones: As potential α-amylase inhibitors and radical (DPPH & ABTS) scavengers. Scientific Reports, 2017, 7, 16980.

U. Salar, K. M. Khan, J. Iqbal, S. A. Ejaz, A. Hameed, M. Al-Rashida, S. Perveen, M. N. Tahir, Coumarin sulfonates: new alkaline phosphatase inhibitors; in vitro and in silico studies. European Journal of Medicinal Chemistry, 2017, 131, 29-47.
U. Salar, K. M. Khan, M. Taha, N. H. Ismail, B. Ali, Qurat-ul-Ain, S. Perveen, M. Ghufran, A. Wadood, Biology-oriented drug synthesis (BIODS): In vitro β-glucuronidase inhibitory and in silico studies on 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl aryl carboxylate derivatives. European Journal of Medicinal Chemistry, 2017, 125, 1289-1299.

U. Salar, K. M. Khan, S. Syed, M. Taha, F. Ali, N. H. Ismail, S. Perveen, A. Wadood, M. Ghufran, Synthesis, in vitro β-glucuronidase inhibitory activity and in silico studies of novel (E)-4-aryl-2-(2-(pyren-1-ylmethylene)hydrazinyl)thiazoles. Bioorganic Chemistry, 2017, 70, 199-209.

F. Ali, K. M. Khan, U. Salar, M. Taha, N. H. Ismail, A. Wadood, M. Riaz, S. Perveen, Hydrazinyl arylthiazole based pyridine scaffolds: Synthesis, structural characterization, in vitro α-glucosidase inhibitory activity, and in silico studies. European Journal of Medicinal Chemistry, 2017, 138, 255-272.

S. Mirza, S. A. Naqvi, K. M. Khan, U. Salar, M. I. Choudhary, Facile synthesis of novel substituted aryl-thiazole (SAT) analogs via one-pot multi-component reaction as potent cytotoxic agents against cancer cell lines. Bioorganic Chemistry, 2017, 70, 133-143.

H. Zafar, M. Hayat, S. Saied, M. Khan, U. Salar, R. Malik, M. I. Choudhary, K. M. Khan, Xanthine oxidase inhibitory activity of nicotino/isonicotinohydrazides: A systematic approach from in vitro, in silico to in vivo studies. Bioorganic and Medicinal Chemistry, 2017, 25, 2351-2371.

T. Arshad, K. M. Khan, N. Rasool, U. Salar, S. Hussain, H. Asghar, M. Ashraf, A. Wadood, M. Riaz, S. Perveen, M. Taha, N. H. Ismail, 5-Bromo-2-aryl benzimidazole derivatives as non-cytotoxic potential dual inhibitors of α-glucosidase and urease enzymes. Bioorganic Chemistry, 2017, 72, 21-31.

M. Taha, S. Imran, N. H. Ismail, M. Selvaraj, F. Rahim, S. Chigurupati, H. Ullah, F. Khan, U. Salar, S. Vijayabalan, K. Zaman, K. M. Khan, Biology-oriented drug synthesis (BIODS) of 2-(2-methyl-5-nitro-1H-imidazol-1-yl) ethyl aryl ether derivatives, in vitro α-amylase inhibitory activity and in silico studies. Bioorganic Chemistry, 2017, 74, 1-9.

M. Taha, F. Rahim, S. Imran, N. H. Ismail, H. Ullah, M. Selvaraj, M. T. Javid, U. Salar, M. Ali, K. M. Khan, Synthesis, α-glucosidase inhibitory activity and in silico study of tris-indole hybrid scaffold with oxadiazole ring: As potential leads for the management of type-II diabetes mellitus. Bioorganic Chemistry, 2017, 74, 30-40.

M. Taha, M. S. Baharudin, N. H. Ismail, M. Selvaraj, U. Salar, K. A. A. Alkadi, K. M. Khan, Synthesis and in silico studies of novel sulfonamides having oxadiazole ring: As β-glucuronidase inhibitors. Bioorganic Chemistry, 2017, 71, 86-96.

S. Iqbal, M. Saleem, M. K. Azim, M. Taha, U. Salar, K. M. Khan, S. Perveen, M. I. Choudhary, Carbohydrazones as new class of carbonic anhydrase inhibitors: synthesis, kinetics, and ligand docking studies. Bioorganic Chemistry, 2017, 72, 89-101.

F. Rahim, Samreen, H. Ullah, M. I. Fakhri, U. Salar, S. Perveen, K. M. Khan, M. I. Choudhary, Anti-Leishmanial activities of synthetic biscoumarins. Journal of the Chemical Society of Pakistan, 2017, 39, 79-82.

U. Salar, K. M. Khan, A. Jabeen, Bakhtawar, A. Faheem, M. Taha, F. Ali, S. Syed, Kanwal, S. M. Haider, S. Perveen, Anti-inflammatory activity of 3-thiazolyl coumarins. Journal of the Chemical Society of Pakistan, 2017, 39, 578-585.

U. Salar, M. Taha, K. M. Khan, N. H. Ismail, S. Imran, S. Perveen, S. Gul, A. Wadood, Syntheses of new 3-thiazolylcoumarin derivatives, in vitro α-glucosidase inhibitory activity, and molecular modeling studies. European Journal of Medicinal Chemistry, 2016, 122, 196-204.

U. Salar, K. M. Khan, A. Jabeen, A. Faheem, M. I. Fakhri, S. M. Saad, S. Perveen, M. Taha, Coumarin sulfonates: As potential leads for ROS inhibition. Bioorganic Chemistry, 2016, 69, 37-47.

U. Salar, M. Taha, N. H. Ismail, K. M. Khan, S. Imran, S. Perveen, A. Wadood, M. Riaz, Thiadiazole derivatives as new class of β-glucuronidase inhibitors. Bioorganic and Medicinal Chemistry, 2016, 24, 1909-1918.

K. M. Khan, U. Salar, S. Yousuf, F. Naz, M. Taha, S. Tauseef, S. Khan, S. Perveen, 5-Nitroimidazole derivatives and their antimicrobial activity.Journal of the Chemical Society of Pakistan, 2016, 38, 258-265.

F. Ali, K. M. Khan, U. Salar, S. Iqbal, M. Taha, N. H. Ismail, S. Perveen, A. Wadood, M. Ghufran, B. Ali, Dihydropyrimidones: As novel class of β-glucuronidase inhibitors. Bioorganic & Medicinal Chemistry, 2016, 24, 3624-3635.
K. M. Khan, S. Qurban, U. Salar, M. Taha, S. Hussain, S. Perveen, A. Hameed, N. H. Ismail, M. Riaz, A. Wadood, Synthesis, in vitro α-glucosidase inhibitory activity and molecular docking studies of new thiazole derivatives. Bioorganic Chemistry, 2016, 68, 245-258.

T. Arshad, K. M. Khan, N. Rasool, U. Salar, S. Hussain, T. Tahir, M. Ashraf, A. Wadood, M. Riaz, S. Perveen, M. Taha, N. H. Ismail, Syntheses, in vitro evaluation and molecular docking studies of 5-bromo-2-aryl benzimidazoles as α-glucosidase inhibitors. Medicinal Chemistry Research, 2016, 25, 2058-2069.

M. Taha, N. H. Ismail, S. Imran, H. Rashwan, W. Jamil, S. Ali, S. M. Kashif, F. Rahim, U. Salar, K. M. Khan, Synthesis of 6-chloro-2-aryl-1H-imidazo[4,5-b]pyridine derivatives: antidiabetic, antioxidant, β-glucuronidase inhibiton and their molecular docking studies. Bioorganic Chemistry, 2016, 65, 48-56.

M. Taha, N. H. Ismail, S. Imran, F. Rahim, A. Wadood, H. Khan, H. Ullah, U. Salar, K. M. Khan, Synthesis, β-glucuronidase inhibition and molecular docking studies of hybrid bisindole-thiosemicarbazides analogs. Bioorganic Chemistry, 2016, 68, 56-63.

Kanwal, K. M. Khan, B. Fatima, B. Bano, U. Salar, A facile route towards the synthesis of 2-(1H-indol-3-yl)-acetamides using 1,1-carbonyldiimidazole. Journal of the Chemical Society of Pakistan, 2016, 38, 771-774.

F. Mukhtar, K. Stieglitz, S. Ali, A. Ejaz, M. I. Choudhary, M. I. Fakhri, U. Salar, K. M. Khan, Coumarin and biscoumarin inhibit in vitro obesity model. Advances in Biological Chemistry, 2016, 6, 152-168.

M. Maqbool, M. Umar, M. A. Iqbal, M. Ajaib, K. M. Khan, S. Perveen, S. Shah, U. Salar, In vitro assessment of antioxidant activity of Anisomeles indica. International Journal of Biochemistry Research & Review, 2016, 14, 1-7.

K. M. Khan, U. Salar, M. I. Fakhri, M. Taha, A. Hameed, S. Perveen,. W. Voelter, Ultrasound‐assisted, convenient and widely applicable 1, 1′‐carbonyl‐diimidazole‐mediated “one‐pot” synthesis of acyl/sulfonyl hydrazines. Letters in Organic Chemistry, 2015, 12, 637-644.

U. Salar, G. A. Miana, K. M. Khan, F. Naz, N. I. Siddiqui, M. Taha, S. Tauseef, S. Khan, S. Perveen, Biology-oriented syntheses (BIOS) of novel santonic-1, 3, 4-oxadiazole derivatives under microwave-irradiation and their antimicrobial activity. Journal of the Chemical Society of Pakistan, 2015, 37, 1020-1029.

K. Javaid, S. M. Saad, S. Rasheed, S. T. Moin, N. Syed, I. Fatima, U. Salar, K. M. Khan, S. Perveen, M. I. Choudhary, 2-Arylquinazolin-4 (3H)-ones: A new class of α-glucosidase inhibitors. Bioorganic and Medicinal Chemistry, 2015, 23, 7417-7421.

K. M. Khan, A. Khan, M. Taha, U. Salar, A. Hameed, N. H. Ismail, W. Jamil, S. M. Saad, S. Perveen, S. M. Kashif, Synthesis of 4-amino-1,5-dimethyl-2-phenylpyrazolone derivatives and their antioxidant activity. Journal of the Chemical Society of Pakistan, 2015, 37, 802-810.

M. Taha, N. H. Ismail, W. Jamil, K. M. Khan, U. Salar, S. M. Kashif, F. Rahim, Y. Latif, Synthesis and evaluation of unsymmetrical heterocyclic thioureas as potent β-glucuronidase inhibitors. Medicinal Chemistry Research, 2015, 24, 3166-3173.