Member Profile
Membership type: full
PhD Fellowship Alumna
Dorothy Akinyi Okoth
Country of origin: Kenya Currently in: Kenya, Kisumu General field of specialization: Chemical SciencesPhD Fellowship Alumna
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Degrees
2014 Doctorate Chemical Sciences -
Current Research Activities
Chemical Sciences
Search for secondary metabolites from plants, fungi and bacteria with potential to be used in disease management. The research entails chromatographic isolation of natural products followed by spectroscopic elucidation of their structures and determination of bioactivity; antibacterial, antimalarial, anticancer, antioxidant etc.
Publications resulting from Research:
Dorothy, O. A. (2014). Phytochemistry and bioactive natural products from Lannea alata, Lannea rivae, Lannea schimperi and Lannea schweinfurthii (anacardiaceae). (Doctor of Philosophy), University of KwaZulu Natal, Durban.
Jondiko JIO, A. D., Ndong'a MF. (2009). Mosquito repellency and larvicidal activities of essential oils from the seeds of annatto (Bixa orellana L.). . In H. N. Bruce TFC, Keys A, Kunert K,Lawlor D, Parry M, Russell G (Ed.), Proceedings of 'Agriculture: Africa's "engine for growth" - plant science and biotechnology-Aspects of Applied Biology. (Vol. 96, pp. 337-342).
Okoth, D. A., Akala, H. M., Johnson, J. D., & Koorbanally, N. A. (2016). Alkyl phenols, alkenyl cyclohexenones and other phytochemical constituents from Lannea rivae (chiov) Sacleux (Anacardiaceae) and their bioactivity. Medicinal Chemistry Research, 25(4), 690-703. doi:10.1007/s00044-016-1521-2
Okoth, D. A., Chenia, H. Y., & Koorbanally, N. A. (2013). Antibacterial and antioxidant activities of flavonoids from Lannea alata (Engl.) Engl. (Anacardiaceae). Phytochemistry Letters, 6(3), 476-481. doi:https://doi.org/10.1016/j.phytol.2013.06.003
Okoth, D. A., Hug, J. J., Garcia, R., & Müller, R. (2022a). Discovery, Biosynthesis and Biological Activity of a Succinylated Myxochelin from the Myxobacterial Strain MSr12020. Microorganisms, 10(10). doi:10.3390/microorganisms10101959
Okoth, D. A., Hug, J. J., Garcia, R., & Müller, R. (2022b). Three New Stigmatellin Derivatives Reveal Biosynthetic Insights of Its Side Chain Decoration. Molecules, 27(14). doi:10.3390/molecules27144656
Okoth, D. A., Hug, J. J., Garcia, R., Spröer, C., Overmann, J., & Müller, R. (2020). 2-Hydroxysorangiadenosine: Structure and Biosynthesis of a Myxobacterial Sesquiterpene-Nucleoside. Molecules, 25(11). doi:10.3390/molecules25112676
Okoth, D. A., Hug, J. J., Mándi, A., Kurtán, T., Garcia, R., & Müller, R. (2021). Structure and biosynthesis of sorangipyranone - a new γ-dihydropyrone from the myxobacterial strain MSr12020. J Ind Microbiol Biotechnol, 48(3-4). doi:10.1093/jimb/kuab029
Okoth, D. A., & Koorbanally, N. A. (2015). Cardanols, long chain cyclohexenones and cyclohexenols from Lannea schimperi (Anacardiaceae). Nat Prod Commun, 10(1), 103-106.
Current profession
Current professional activities type:ResearchAdministrationTeachingHigher Education StudyA researcher and lecturer at Maseno University Kenya
Affiliations
Kenya Chemical SocietyHumboldt Foundation Fellowship -
Fellowship with OWSD
Fellowship with OWSD
Fellowship awarded 2010