Ghanya Naji Mohammed Al-Naqeb

A- Publications with peer review process:

1. Kalmpourtzidou, A.; De Giuseppe, R.; Vincenti, A.; Al-Naqeb, G.; Cena, H. The Effect of Nature-Based Solutions on Human Nutrition and Food Security in Urban Settings. Proceedings 2023, 91, 214. https://doi.org/10.3390/proceedings202309121.

2. Al-Naqeb, G.; Kalmpourtzidou, A.; De Giuseppe, R.; Cena, H. Beneficial Effects of Plant Oils Supplementation on Multiple Sclerosis: A Comprehensive Review of Clinical and Experimental Studies. Nutrients 2023, 15, 4827. https:// doi.org/10.3390/nu15224827.

3. Al-Naqeb, G., Cafarella, C., Aprea, E., Ferrentino, G., Gasparini, A., Buzzanca, C., Micalizzi, G., Dugo, P., Mondello, L., Rigano, F. (2023). Supercritical Fluid Extraction of Oils from Cactus Opuntia ficus-indica L. and Opuntia dillenii Seeds. Foods, 12, 618. https://doi.org/10.3390/foods12030618.
4. Al-Naqeb, G., Sidarovich, V., Scrinzi, D., Mazzeo, I., Robbiati, S., Pancher, M., Fiori, L., & Adami, V. (2022). Hydrochar and hydrochar co-compost from OFMSW digestate for soil application: 3. Toxicological evaluation. Journal of environmental management, 320, 115910. https://doi.org/10.1016/j.jenvman.2022.115910.
5. Al-Naqeb, G.; Fiori, L.; Ciolli, M.; Aprea, E. (2021). Prickly Pear Seed Oil Extraction, Chemical Characterization and Potential Health Benefits. Molecules, 26, 5018. https://doi.org/10.3390/molecules26165018.
6. Al-Naqeb, G. (2020). Antioxidants activity and cholesterol regulation effect of Caralluma flava N.E.Br extract in HepG2 cells. Arabian Journal of Medicinal and Aromatic Plants, 6(3), 57-75. doi:https://doi.org/10.48347/IMIST.PRSM/ajmap-v6i3.23655.
7. Kaokabah, N., Al-Qubati, A., Al-Naqeb, G. (2020). Anti-Obesity Effects of Pulicaria Jaubertii E. Gamal-Eldin in High Fat Diet-Induced Rats. Universal Journal of Pharmaceutical Research, Vol. 5, no. 5, Nov. doi: https://doi.org/10.22270/ujpr.v5i5.487.
8. Al-Naqeb, G. (2017). Acute toxicity and anti-ulcerative potential of caralluma flava N.E.Br methanolic extract against ethanol-induced gastric ulcers in rats. Journal of Medicinal Plants Studies. 5(6): 21-25.
9. Al-Naqeb, G. (2017). Caralluma flava N.E.Br extract reduces plasma glucose level and improves plasma antioxidant enzymes in hyperglycemic rats. Journal of Medicinal Plants Studies. 5(6): 39-43. 2017.
10. Al-Naqeb, G., Taj Al- Deen, A. (2017). The effect of Rumex nervosus Vahl leaves on high fat diet-induced hyperglycemia and hyperlipidemia in albino rats. International Journal of Chemical Science. 1(2), 80-83.
11. Al-Naqeb, G., Rousová, J., Kubátová, A., & Picklo, M. J., Sr (2016). Pulicaria jaubertii E. Gamal-Eldin reduces triacylglyceride content and modifies cellular antioxidant pathways in 3T3-L1 adipocytes. Chemico-biological interactions, 253, 48–59. https://doi.org/10.1016/j.cbi.2016.05.013.
12. Al-Naqeb, G. (2015). Effect of prickly pear cactus seeds oil on the blood glucose level of streptozotocin-induced diabetic rats and its molecular mechanisms. International Journal of Herbal Medicine. 3(4): 2934.
13. Al-Naqeb, G. (2015). Antioxidant and Antibacterial Activities of Some Yemeni Medicinal Plants. International Journal of Herbal Medicine 2015; 3(3): 06-11.
14. Mohd Ghazali, M. A., Al-Naqeb, G., Krishnan Selvarajan, K., Hazizul Hasan, M., & Adam, A. (2014). Apoptosis Induction by Polygonum minus is related to antioxidant capacity, alterations in expression of apoptotic-related genes, and S-phase cell cycle arrest in HepG2 cell line. BioMed research international, 2014, 539607. https://doi.org/10.1155/2014/539607.
15. Wesam, R. K., Ghanya, A. N., Mizaton, H. H., Ilham, M., & Aishah, A. (2013). Assessment of genotoxicity and cytotoxicity of standardized aqueous extract from leaves of Erythroxylum cuneatum in human HepG2 and WRL68 cells line. Asian Pacific journal of tropical medicine, 6(10), 811–816. https://doi.org/10.1016/S1995-7645(13)60143-1.
16. Taj Al- Deen, A., Al-Naqeb, G., Al-Maqtari. Q., (2013). Potential antioxidants and antibacterial from Dodonaea viscose, Fragaria x ananassa duch and Vernonia amygdalina leaves. University of Aden Journal of Natural and Applied Sciences, 17, 2013.

17. Azahar, M. A., Al-Naqeb, G., Hasan, M., & Adam, A. (2012). Hypoglycemic effect of Octomeles sumatrana aqueous extract in streptozotocin-induced diabetic rats and its molecular mechanisms. Asian Pacific journal of tropical medicine, 5(11), 875–881. https://doi.org/10.1016/S1995-7645(12)60163-
18. John, C. M., Ramasamy, R., Al Naqeeb, G., Dhiab Al-Nuaimi, A. H., & Adam, A. (2012). Enhanced CD4+CD25+ regulatory T cells with splenic proliferation and protection against oxidative stress by nicotinamide in gestational diabetes. Current medicinal chemistry, Advance online publication.
19. John, C. M., Ramasamy, R., Al Naqeeb, G., Al-Nuaimi, A. H., & Adam, A. (2012). Nicotinamide supplementation protects gestational diabetic rats by reducing oxidative stress and enhancing immune responses. Current medicinal chemistry, 19(30), 5181–5186. https://doi.org/10.2174/092986712803530449.
20. Al-Naqeep, G., Al-Zubairi, A. S., Ismail, M., Amom, Z. H., & Esa, N. M. (2011). Antiatherogenic Potential of Nigella sativa Seeds and Oil in Diet-Induced Hypercholesterolemia in Rabbits. Evidence-based complementary and alternative medicine: eCAM, 2011, 213628. https://doi.org/10.1093/ecam/neq071.
21. Ismail, N., Ismail, M., Al-Absi A., Al-Naqeeb, G. (2011). Thymoquinone rich fraction from Nigella sativa and thymoquinone are cytotoxic towards colon and leukemic carcinoma cell lines. Journal of Medicinal Plants Research. 2011, Vol. 5(15), 3359–3366.
22. Al-Naqeb, G. Ismail, M., Bagalkotkar, G., Adamu, H. (2010). Vanillin rich fraction regulates LDLR and HMGCR genes expression in HepG2 cells. Food Research International 43 2437–2443. https://doi.org/10.1016/j.foodres.2010.09.015.
23. Ismail, M., Al-Naqeep, G., Chan, K. W. (2010). Nigella sativa thymoquinone-rich fraction greatly improves plasma antioxidant capacity and expression of antioxidant genes in hypercholesterolemic rats. Free radical biology & medicine, 48(5), 664–672. https://doi.org/10.1016/j.freeradbiomed.2009.12.002.
24. Mariod, A.A., Al-Naqeep, G., Ismail, M. (2010). Monechma ciliatum methanolic extract regulates low density lipoprotein receptor and 3-hydroxy-3- methylglutaryl coenzyme A reductase genes expression in HepG2 cells. 9(36) 5813-5819.
25. Ismail, M., Al-Naqeeb, G., Mamat, W. A., & Ahmad, Z. (2010). Gamma-oryzanol rich fraction regulates the expression of antioxidant and oxidative stress related genes in stressed rat's liver. Nutrition & metabolism, 7, 23. https://doi.org/10.1186/1743-7075-7-23.
26. Al-Naqeep, G., Ismail, M., & Allaudin, Z. (2009). Regulation of low-density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression by thymoquinone-rich fraction and thymoquinone in HepG2 cells. Journal of nutrigenetics and nutrigenomics, 2(4-5), 163–172. https://doi.org/10.1159/000227264.
27. Al-Naqeep, G., Ismail, M. (2009). Effects of Thymoquinone Rich Fraction and Thymoquinone on plasma lipoprotein level and hepatic low-density lipoprotein receptor and 3-Hydroxy-3methylglutaryl coenzyme A reductase gene expression. Journal of Functional Foods 1 (2009) 298–303. https://doi.org/10.1016/j.jff.2009.06.003.

28. Al-Naqeep, G.N., M.M. Ismail, A.S. Al-Zubairi and N.M. Esa. (2009). Nutrients composition and minerals content of three different samples of Nigella sativa L. cultivated in Yemen. Asian Journal of Biological Sciences, 2: 43-48.

29. Al-Naqeep, G., Ismail, M., (2009). Regulation of Apolipoprotien A-1 and Apolipoprotien B100 Genes by Thymoquinone Rich Fraction and Thymoquinone in HepG2 Cells. Journal of Food Lipids16(2009) 245–258.

30. Al-Naqeeb, G., M. Ismail and A.S. Al-Zubairi. (2009). Fatty acid profile, α-tocopherol content and total antioxidant activity of oil extracted from Nigella sativa seeds. International Journal of Pharmacology. 5 (4): 244-250. Impact factor 0.751.

31. Yazan, L.S., Ng, W.K., Al-Naqeeb, G., Ismail, M. (2009). Cytotoxicity of Thymoquinone (TQ) from Nigella sativa Towards Human Cervical Carcinoma Cells (HeLa). Journal of Pharmacy Research, 2(4), 585-589. Impact factor 0. Citation 34.

B- (Conference paper)

32. Aliki Kalmpourtzidou1, Beatrice Maccarini1, Ghanya Al-Naqeb1, Rachele de Giuseppe 1, Hellas Cena. The effect of urban gardening/farming on human nutrition and wellbeing: a systematic review. Belgrade, Serbia. 14-17th November 2023.
33. Al-Naqeb, G. (2022). Genotoxicity Evaluation of Prickly Pear Cactus Seeds Oil in Cultured V79 Cells. September 2022. DOI: 10.21748/ZIFS8532. Conference: 2022 AOCS Annual Meeting & Expo.
34. Antiadipogenic properties, Chemical characterization and Genotoxicity Approaches of Pulicaria Jaubertii E. Gamal-Eldin leaves Extract Originated from Yemen.
35. Ghanya Al-Naqeb, Harald L. Esch, Carolin Kleider, Matthew J. Picklo Sr, Leane Lehmann:
36. 19th International Congress of the International Society for Ethnopharmacology (12th-14th June 2019) “ Hörsaalzentrum of the Technische Universität Dresden. 12th-14th June 2019.
37. https://tu-dresden.de/mn/internationales/veranstaltungen/symposien-kolloquien/2019-international-ethnopharmacological-congress



38. Picklo M, Rousova J, Kubatova, Al-Neqeb G. (2015). Pulicaria jaubertii Extract Prevents Triglyceride Deposition in 3T3-L1 Adipocytes. FASEB J, 29(1):924.19.

39. Kraidi, S., Adam, A., Iryani, W., Al-Naqeb, G. (2013). Antiproliferative Effect of Antioxidant Rich Fraction Isolated from Cassia Auriculat and its Molecular Mechanisms. The Open Conference Proceedings Journal, 2013, Volume 4. 10.2174/2210289201304010228.

C – Patents

40. Ismail, M., Al-Naqeeb, G. Cardioprotective Effects of Nutraceuticals Isolated from Nigella Sativa Seeds. US Patent App. 13/124,370, 2011.
Publication of US20110244060A1. 2011-10-06.
41. M Ismail, G Al-Naqeeb, W Chan, NE Adnan Extraction of fixed oil and thymoquinone rich fraction - US Patent App. 13/832,499, 2013.
2012-02-23. Publication of US20120046366A1
https://patents.google.com/patent/US20110244060A1/en