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Membership type: full

Melissa Dalcina Chengalroyen

Country of origin: South Africa Currently in: South Africa, Cape Town General field of specialization: Structural, Cell and Molecular Biology
Academic Background

Degrees

2011 Doctorate Structural, Cell and Molecular Biology
Research and Profession

Current Research Activities

Other

Mycobacteriology

Research Keywords: 
Mycobacteria
CRISPRi
Antimycobacterial drug screening

Publications resulting from Research: 


Chengalroyen M.D., Beukes G.M., Gordhan B.G., Streicher E.M., Churchyard G., Hafner R., Warren R., Otwombe K., Martinson N. and Kana B.D., (2016). Detection and quantification of differentially culturable tubercle bacteria in sputum from tuberculosis patients, American Journal of Respiratory and Critical Care Medicine, DOI:10.1164/rccm.201604-0769OC

Hadebe S., Chengalroyen M., Guler R., Nakedi K., Koch A., Makatsa M., Shey M., Parihar S.P., Bryson B., Marakalala M.J., Ndlovu H. (2020). Intervening along the spectrum of tuberculosis: meeting report from the World TB Day nanosymposium in the Institute of Infectious Disease and Molecular Medicine at the University of Cape Town. Gates Open Res. 3:1491. doi: 10.12688/gatesopenres.13035.4

Kieswetter N.S., Ozturk M., Jones S.S., Senzani S., Chengalroyen M.D., Brombacher F., Kana B., Guler R., (2021). Deletion of N-acetylmuramyl-L-alanine amidases alters the host immune response to Mycobacterium tuberculosis infection. Virulence. 2021 Dec;12(1):1227-1238. doi: 10.1080/21505594.2021.1914448

Chengalroyen M.D., Jordaan A., Seldon R., Ioerger T., Franzblau S.G., Nasr M., Warner D.F., Mizrahi V., (2020). Biological Profiling Enables Rapid Mechanistic Classification of Phenotypic Screening Hits and Identification of KatG Activation-Dependent Pyridine Carboxamide Prodrugs with activity against Mycobacterium tuberculosis. Front Cell Infect Microbiol, 13;10:582416. doi: 10.3389/fcimb.2020.582416. PMID: 33282750; PMCID: PMC7691319



Current profession

Current professional activities type: 
Research

Workshop and Conference Attended

2019 Cape Town, South Africa World Tuberculosis Day Nano Symposium

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