Full Member
Ambeu-Loko N'ta Christelle Mélissa
Membership since:
2025
Field of activity:
Awards
Other Memberships/Affiliations
University of Nantes
Degrees:
2015
Doctorate Chemical Sciences
The theme of doctoral research is : Synthesis of pentamidine analogs bearing heterocyclic platforms (rhodanine, benzimidazole, pyrazole and imidazole) and their biological evaluations. The thesis manuscript is focused on the development of multi-steps synthesis strategy of new compounds bearing several heterocyclic platforms for multiple therapeutic use to fight malaria, leishmaniasis, cancer and neurodegenerative diseases. Thus, this research work led to the synthesis of 169 compounds. The compounds synthesized in this research work were evaluated for their antiproliferative activity on tumoral cell lines and for their inhibitory activity on protein kinases.
Publications resulting from Research
P1. FANTE Bamba, AMBEU-LOKO N’ta Christelle Mélissa, COULIBALY Souleymane, SORO Yaya et COUSTARD Jean-Marie
An Original Transposition of 4-Fluorobenzylamino Group from 1-(4-Fluorobenzylamino)-1-methylsulfanyl-2-nitroethylene in Triflic Acid
Organic Preparations and Procedures International 2023, DOI:10.1080/00304948.2023.2178212
P2. Coulibaly Wacothon Karime, Affi Sopi Thomas, James Titah, Mamadou Guy-Richard Koné, Affoué Estelle Brigitte Yao, Camille Déliko Dago, Christelle N’ta Ambeu, Jean-Pierre Bazureau, Josh Daniel McLoud, Benié Anoubilé, Nahossé Ziao
Anti-proliferative Activity Study on 5-Arylidene Rhodanine Derivatives Using Density Functional Theory (DFT) and Quantitative Structure Activity Relationship (QSAR)
International Journal of Computational and Theoretical Chemistry 2022; 10(1): pp. 1-8
P3. Wacothon Karime Coulibaly, Jean Stéphane N’dri, Mamadou Guy-Richard Koné, Camille Déliko Dago, Christelle N’ta Ambeu, Jean-Pierre Bazureau, Nahossé Ziao
Studies of the Chemical Reactivity of a Series of Rhodanine Derivatives by Approaches to Quantum Chemistry
Computational Molecular Bioscience 2019, 9, pp. 49-62.
P4. Christelle N'Ta Ambeu, Rémy Le Guével, Anne Corlu, Janat Akhanovna Mamyrbekova and Jean-Pierre Bazureau
A practical multi-step synthesis of ethyl N-functionalized β-aminobenzimidazole acrylate derivatives as promising cytotoxic agents
Molecular Diversity 2018, 22(3), pp. 685-708.
P5. Camille Déliko Dago, Christelle N'ta Ambeu, Wacothon Karime Coulibaly, Yves-Alain Békro, Janat A. Mamyrbekova-Békro, Rémy Le Guével, Anne Corlu and J-P. Bazureau.
Investigation on the synthesis of new 3-(4-(arylalkoxy)phenylethyl)-2-thioxo-1,3-thiazolidine-4-ones and their biological evaluation against cancer cells.
Chemistry of Heterocyclic Compounds 2017, 53(3), pp. 341–349.
P6. Christelle N'ta Ambeu, Camille Déliko Dago, Wacothon Karime Coulibaly, Yves-Alain Békro, Janat A. Mamyrbekova-Békro, Béatrice Foll-Josselin, Audrey Defontaine, Claire Delehouzé, Stéphane Bach, Sandrine Ruchaud, Rémy Le Guével, Anne Corlu, Philippe Jéhan, Fabian Lambert, Nicolas Le Yondre and J-P. Bazureau
Microwave synthesis of new 3-(3-aminopropyl)-5-arylidene-2-thioxo-1,3-thiazolidine-4-ones as potential Ser/Thr protein kinase inhibitors
Medicinal Chemistry Research 2016, 25, pp. 2940–2958.
P7. Christelle N’ta Ambeu; Camille Déliko Dago; Wacothon Karime Coulibaly; Yves-Alain Békro; Janat A. Mamyrbekova-Békro; Jean-Pierre Bazureau.
Microwave Assisted Prospective Synthesis of New 5-Arylidene Rhodanine Derivatives Bearing a 3-[4-(3-Aminopropyl)-piperazin-1-yl]propyl Side Chain
Current Microwave Chemistry 2016, vol.3, number 2, pp.145-156 (12).
P8. Camille Déliko Dago, Christelle N'ta Ambeu, Wacothon Karime Coulibaly, Yves-Alain Békro, Janat A. Mamyrbekova-Békro, Audrey Defontaine, Blandine Baratte, Stéphane Bach, Sandrine Ruchaud, Rémy Le Guével, Myriam Ravache, Anne Corlu, Jean Pierre Bazureau.
Synthetic development of new 3-(4-arylmethylamino)butyl-5-arylidene-rhodanines under microwave irradiation and their effects on tumor cell lines and against protein kinases.
Molecules 2015, 20, pp.12412-12435.
P9. KABRAN Guy Roger, AMBEU N’ta Christelle M., MAMYRBEKOVA-BÉKRO Janat Akhanovna, BÉKRO Yves-Alain
Phénols et Flavonoïdes Totaux Dans Les Extraits Organiques de Dix Plantes Utilisées Dans la Tradithérapie du Cancer du Sein en Côte d’Ivoire
European Journal of Scientific Research 2012, 68(2), pp.182-190.
P10. KABRAN Guy Roger Mida, AMBEU N’ta Christelle, MAMYRBEKOVA-BÉKRO Janat Akhanovna, BÉKRO Yves-Alain
CCM D’extraits Sélectifs de 10 Plantes Utilisées Dans le Traitement Traditionnel du Cancer du Sein en Côte d’Ivoire
European Journal of Scientific Research 2011, 63(4), pp. 592-603.
An Original Transposition of 4-Fluorobenzylamino Group from 1-(4-Fluorobenzylamino)-1-methylsulfanyl-2-nitroethylene in Triflic Acid
Organic Preparations and Procedures International 2023, DOI:10.1080/00304948.2023.2178212
P2. Coulibaly Wacothon Karime, Affi Sopi Thomas, James Titah, Mamadou Guy-Richard Koné, Affoué Estelle Brigitte Yao, Camille Déliko Dago, Christelle N’ta Ambeu, Jean-Pierre Bazureau, Josh Daniel McLoud, Benié Anoubilé, Nahossé Ziao
Anti-proliferative Activity Study on 5-Arylidene Rhodanine Derivatives Using Density Functional Theory (DFT) and Quantitative Structure Activity Relationship (QSAR)
International Journal of Computational and Theoretical Chemistry 2022; 10(1): pp. 1-8
P3. Wacothon Karime Coulibaly, Jean Stéphane N’dri, Mamadou Guy-Richard Koné, Camille Déliko Dago, Christelle N’ta Ambeu, Jean-Pierre Bazureau, Nahossé Ziao
Studies of the Chemical Reactivity of a Series of Rhodanine Derivatives by Approaches to Quantum Chemistry
Computational Molecular Bioscience 2019, 9, pp. 49-62.
P4. Christelle N'Ta Ambeu, Rémy Le Guével, Anne Corlu, Janat Akhanovna Mamyrbekova and Jean-Pierre Bazureau
A practical multi-step synthesis of ethyl N-functionalized β-aminobenzimidazole acrylate derivatives as promising cytotoxic agents
Molecular Diversity 2018, 22(3), pp. 685-708.
P5. Camille Déliko Dago, Christelle N'ta Ambeu, Wacothon Karime Coulibaly, Yves-Alain Békro, Janat A. Mamyrbekova-Békro, Rémy Le Guével, Anne Corlu and J-P. Bazureau.
Investigation on the synthesis of new 3-(4-(arylalkoxy)phenylethyl)-2-thioxo-1,3-thiazolidine-4-ones and their biological evaluation against cancer cells.
Chemistry of Heterocyclic Compounds 2017, 53(3), pp. 341–349.
P6. Christelle N'ta Ambeu, Camille Déliko Dago, Wacothon Karime Coulibaly, Yves-Alain Békro, Janat A. Mamyrbekova-Békro, Béatrice Foll-Josselin, Audrey Defontaine, Claire Delehouzé, Stéphane Bach, Sandrine Ruchaud, Rémy Le Guével, Anne Corlu, Philippe Jéhan, Fabian Lambert, Nicolas Le Yondre and J-P. Bazureau
Microwave synthesis of new 3-(3-aminopropyl)-5-arylidene-2-thioxo-1,3-thiazolidine-4-ones as potential Ser/Thr protein kinase inhibitors
Medicinal Chemistry Research 2016, 25, pp. 2940–2958.
P7. Christelle N’ta Ambeu; Camille Déliko Dago; Wacothon Karime Coulibaly; Yves-Alain Békro; Janat A. Mamyrbekova-Békro; Jean-Pierre Bazureau.
Microwave Assisted Prospective Synthesis of New 5-Arylidene Rhodanine Derivatives Bearing a 3-[4-(3-Aminopropyl)-piperazin-1-yl]propyl Side Chain
Current Microwave Chemistry 2016, vol.3, number 2, pp.145-156 (12).
P8. Camille Déliko Dago, Christelle N'ta Ambeu, Wacothon Karime Coulibaly, Yves-Alain Békro, Janat A. Mamyrbekova-Békro, Audrey Defontaine, Blandine Baratte, Stéphane Bach, Sandrine Ruchaud, Rémy Le Guével, Myriam Ravache, Anne Corlu, Jean Pierre Bazureau.
Synthetic development of new 3-(4-arylmethylamino)butyl-5-arylidene-rhodanines under microwave irradiation and their effects on tumor cell lines and against protein kinases.
Molecules 2015, 20, pp.12412-12435.
P9. KABRAN Guy Roger, AMBEU N’ta Christelle M., MAMYRBEKOVA-BÉKRO Janat Akhanovna, BÉKRO Yves-Alain
Phénols et Flavonoïdes Totaux Dans Les Extraits Organiques de Dix Plantes Utilisées Dans la Tradithérapie du Cancer du Sein en Côte d’Ivoire
European Journal of Scientific Research 2012, 68(2), pp.182-190.
P10. KABRAN Guy Roger Mida, AMBEU N’ta Christelle, MAMYRBEKOVA-BÉKRO Janat Akhanovna, BÉKRO Yves-Alain
CCM D’extraits Sélectifs de 10 Plantes Utilisées Dans le Traitement Traditionnel du Cancer du Sein en Côte d’Ivoire
European Journal of Scientific Research 2011, 63(4), pp. 592-603.
30th french-belgian Days (JFB) of pharmacochemistry
2025
Amboise, FranceSynthesis of ethyl N-functionalized β-amino benzimidazole acrylate derivatives and their cytotoxic biological evaluation
2025
http://www.sciforum.net/conference/ecmc-3; https://sciforum.net/manuscripts/4687/manuscript.pdf