Full Member
Celia Quijano
Membership since:
2025
Field of activity:
Awards
Other Memberships/Affiliations
Society for Free Radical Biology and Medicine (SFRBM)
Publications resulting from Research
Demicheli V, Moreno D, Jara G, Lima A, Carballal S, Rios N, Batthyany C, Ferrer- Sueta G, Quijano C, Estrín D, Martí M, Radi R.
Mechanism of the Reaction of human Mn-Superoxide Dismutase with Peroxynitrite: Nitration of Critical Tyrosine-34. Biochemistry, 2016. [Epub ahead of print].
Quijano C, Trujillo M, Castro L, Trostchansky A. Interplay between oxidant species and energy metabolism. Redox Biol. 2016; 8:28-42.
Martino Adami PV, Quijano C, Magnani N, Galeano P, Evelson P, Cassina A, Do Carmo S, Leal MC, Castaño EM, Cuello AC, Morelli L. Synaptosomal bioenergetic defects are associated with cognitive impairment in a transgenic rat model of early Alzheimer's disease. J Cereb Blood Flow Metab. 2015 [Epub ahead of print]
Quijano C, Cao L, Fergusson MM, Romero H, Liu J, Gutkind S, Rovira II, Mohney RP, Karoly ED, Finkel T. Oncogene-induced senescence results in marked metabolic and bioenergetic alterations. Cell Cycle. 2012; 11(7):1383-92.
Valez V, Aicardo A, Cassina A, Quijano C, Radi R. Oxidative Stress in Mitochondria Principles of Free Radical Biomedicine. Editors: K. Pantopoulos and H. Schipper. Nova Science Publishers Inc. 2012; 2:283 – 302.
Yadav H, Quijano C, Kamaraju KA, Gavrilova O, Malek R, Chen W, Zerfas P, Zhigang D, Wright EC, Stuelten C, Sun P, Lonning S, Skarulis M, Sumner AE, Finkel T, and Rane SG. Protection from Obesity and Diabetes by Blockade of TGF-b/Smad3 Signaling. Cell Metabolism. 2011; 14:67-79.
Wu JJ, Quijano C, Wang J, Finkel T. Metabolism meets autophagy. Cell Cycle. 2010; 9:4780-4781.
Wu JJ, Quijano C, Chen E, Liu H, Fergusson MM, Rovira II, Gutkind S, Daniels MP, Komatsu M and Finkel T. Mitochondrial dysfunction and oxidative stress mediate physiological impairment induced by the disruption of autophagy. Aging. 2009; 1:425-437.
Hernandez-Saavedra D, Quijano C, Demicheli V, Souza JM, Radi R, McCord JM. Thiol-sensitive mutant forms of human SOD2, L60F, and I58T: The role of Cys 140. Free Radic. Biol. Med. 2010; 48:1202-1210.
Redondo-Horcajo M, Romero N, Martínez-Acedo P, Martínez-Ruiz A, Quijano C, Lourenço CF, Movilla N, Enríquez JA, Rodríguez-Pascual F, Rial E, Radi R, Vázquez J, Lamas L. Cyclosporine A-Induced Nitration of Tyrosine 34 MnSOD in Endothelial Cells: Role of Mitochondrial Superoxide. Cardiovasc Res. 2010; 87:356-365.
Liu J, Cao L, Chen J, Song S, Lee I, Quijano C, Liu H, Keyvanfar K, Chen H, Cao L, Ahn B, Kumar NJ, Rovira II, Daniels MP, Xu X, van Lohuizen M, Motoyama N, Deng C and Finkel T. Deletion of Bmi1 induces oxidative stress and activates the DNA damage response pathway. Nature. 2009; 459:388-393.
González-Pérez S, Quijano C, Romero N, Melø TB, Radi R, Arellano JB. Peroxynitrite inhibits electron transport on the acceptor side of higher plant photosystem II. Arch Biochem Biophys. 2008; 473:25-33.
Quijano C, Castro L, Peluffo G, Valez V and Radi R. Enhanced mitochondrial superoxide formation in hyperglycemic endothelial cells: Direct measurements and formation of hydrogen peroxide and peroxynitrite. Am. J. Physiol. Heart Circ. Physiol. 2007; 293: H340-14.
Demicheli V, Quijano C, Alvarez B, Radi R. Inactivation and nitration of human SODs by fluxes of nitric oxide and superoxide. Nitric oxide reaction with superoxide outcompetes SOD dismutation, generating peroxynitrite. Free Radic. Biol. Med. 2007; 42:1359-1368.
Tortora V, Quijano C, Freeman BA, Radi R, Castro L. Mitochondrial aconitase reaction with nitric oxide, S-nitrosoglutathione and peroxynitrite: Defining de mechanisms and relative contribution of these species to aconitase inactivation. Free Radic. Biol. Med. 2007; 42:1075-88.
Ye Y, Quijano C, Robinson KM, Ricart KC, Strayer AL, Shacka JJ, Kirk M, Barnes S, Radi R, Beckman BS, Estévez AG. Prevention of peroxynitrite-induced apoptosis of motor neurons and PC12 cells by tyrosine containing peptides. J. Biol. Chem. 2007; 282:6324-37.
Quijano C, Cassina A, Castro L, Rodríguez R and Radi R. Peroxynitrite: a mediator of nitric-oxide dependent mitochondrial dysfunction in pathology. Nitric Oxide, Cell Signaling, and Gene Expression. Santiago Lamas and Enrique Cadenas eds. Taylor & Francis Group, Florida. 2006; 99-143.
Quijano C, Romero N and Radi R. Tyrosine nitration by superoxide and nitric oxide fluxes in biological systems: Modeling the impact of superoxide dismutase and nitric oxide diffusion. Free Radic. Biol. Med. 2005; 39, 728-41.
Radi R, Cassina A, Hodara R, Quijano C and Castro L. Peroxynitrite reactions and formation in mitochondria. Free Radic. Biol. Med. 2002; 33, 1451-64.
Ferrer-Sueta G, Quijano C, Alvarez B, Radi R. Reactions of manganese porphyrins and manganese-superoxide dismutase with peroxynitrite. Methods Enzymol. 2002; 349:23-37.
Quijano C, Hernandez-Saavedra D, Castro L, McCord JM, Freeman BA and Radi R. Reaction of peroxynitrite with Mn-superoxide dismutase: Role of the metal center in decomposition kinetics and nitration. J. Biol. Chem. 2001; 276, 11631-8.
Blanchard-Fillion B, Souza JM, Friel T, Jiang GC, Vrana K, Sharov V, Barrón L, Schöneich C, Quijano C, Alvarez B, Radi R, Przedborski S, Fernando GS, Horwitz J, Ischiropoulos H. Nitration and inactivation of tyrosine hydroxylase by peroxynitrite. J Biol Chem. 2001; 276:46017-23.
Cerecetto H, Di Maio R, Gonzalez M, Risso M, Sagrera G, Seoane G, Denicola A, Peluffo G, Quijano C, Stoppani AO, Paulino M, Olea-Azar C, Basombrio MA. Synthesis and antitrypanosomal evaluation of E-isomers of 5-nitro-2-furaldehyde and 5-nitrothiophene-2-carboxaldehyde semicarbazone derivatives. Structure-activity relationships. Eur. J. Med. Chem. 2000; 35:343-50.
Cerecetto H, Di Maio R, González M, Risso M, Saenz P, Seoane G, Denicola A, Peluffo G, Quijano C and Olea-Azar C. 1,2,5,-Oxadiazole N-oxide derivatives and related compounds as potential antitrypanosomal drugs: structure-activity relationships. J. Med. Chem. 1999; 42:1941-1950.
Quijano C, Alvarez B, Gatti RM, Augusto O and Radi R. Pathways of peroxinitrite oxidation of thiol groups. Biochem. J. 1997; 322, 167-73.
Mini-Symposium ICGEB-CEINBIO: Frontiers in Biomedical Research
2025
Montevideo, Uruguay1st Conference of the South American Chapter of Cell Stress Society International
2025
Montevideo, UruguayCold Spring Harbor Laboratory Meeting Molecular Genetics of Aging
2025
Cold Spring Harbor, NY, USA7as Jornadas de la Seccional Bioquímica y Biología Molecular de la Sociedad Uruguaya de Biociencias
2025
Montevideo, UruguayXIII Biennal Meeting of the Society for Free Radical Research International
2025
Davos, Switzerland9th Annual Meeting of the Oxygen Society
2025
San Antonio, Texas, USA Mini-Symposium ICGEB-CEINBIO: Frontiers in Biomedical Research
2025
Uruguay1st Conference of the South American Chapter of Cell Stress Society International
2025
UruguayCold Spring Harbor Laboratory Meeting Molecular Genetics of Aging
2025
USACell Senescence in Cancer and Ageing
2025
Cambridge, United Kingdom23rd Congress of the International Union for Biochemistry and Molecular Biology (IUBMB) and 44th Annual Meeting of the Brazilian Society for Biochemistry and Molecular Biology (SBBq)
2025
BrazilXV Jornadas de la Sociedad Uruguaya de Biociencias
2025
Uruguay8vas Jornadas de la Sociedad de Biooquímica y Biología Molecular
2025
Uruguay7as Jornadas de la Seccional Bioquímica y Biología Molecular de la Sociedad Uruguaya de Biociencias
2025
UruguayGordon Research Conference. Oxygen Radicals
2025
USAV Meeting of the Society for Free Radical Research – South American Group
2025
UruguayXIII Biennal Meeting of the Society for Free Radical Research International
2025
SwitzerlandIV Meeting of the South American Group of the Society for Free Radical Biology and Medicine
2025
BrazilSociety for Free Radical Research 12th Biennal Meeting
2025
Argentina9th Annual Meeting of the Oxygen Society
2025
USA