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Awards

January 2011 National Prize of Cuban Society of Chemistry to Young Scientist in the International Year of Chemistry, 2010.

January 2011 Prize to Best Research Article in Natural Sciences of Havana University, 2011

October 2012 Ciudad Capital: Heberto Castillo

January 2020 Research Prize of Havana University in Natural Sciences 2019

July 2022 Cuban Academy of Sciences 2021

January 2022 Special Distinction of the Ministry of Higher Education of Cuba in Sciences Technology and Innovation 2020.

February 2023 Research prize of the Havana University 2022 To the Result of Higher Impact In basic and Natural Sciences

October 2023 Special Distinction of the Ministry of Higher Education of Cuba 2022 To the Result of Higher Impact In basic and Natural Sciences

February 2024 Research prize of the Havana University 2023 to Distinguished Research Article in Natural Sciences

February 2024 Research Prize Research prize of the Havana University 2023 to Distinguished Researcher

Degrees:

2005
Isel Pascual Alonso > Degrees
Structural, Cell and Molecular Biology

Publications resulting from Research
1. García, F. A., Fuentes, T. F., Pascual Alonso, I. , Bosch, R. A., Brunetti, A. E., & Lopes, N. P. (2024). A Comprehensive Review of Patented Antimicrobial Peptides from Amphibian Anurans. Journal of Natural Products. https://doi.org/10.1021/acs.jnatprod.3c01040
2. Pascual Alonso, I*., Méndez, L. R., García, F. A., Valdés-Tresanco, M. E., Bosch, R. A., Perera, W. H., ... & Charli, J. L. (2023). Bufadienolides preferentially inhibit aminopeptidase N among mammalian metallo-aminopeptidases; relationship with effects on human melanoma MeWo cells. International Journal of Biological Macromolecules, 229, 825-837. https://doi.org/10.1016/j.ijbiomac.2022.12.280
3. Pascual Alonso, I.*; AlmeidaGarcía, F.; Valdés Tresanco, M.E.;Arrebola Sánchez, Y.; Ojeda del Sol,D.; Sánchez Ramírez, B.; Florent, I.;Schmitt, M.; Avilés, F.X. (2023) MarineInvertebrates: A Promissory StillUnexplored Source of Inhibitors of Biomedically Relevant Metallo Aminopeptidases Belonging to the M1 and M17 Families. Mar. Drugs 2023, 21, 279. https://doi.org/10.3390/md21050279
4. Isel Pascual Alonso*, Yarini Arrebola Sánchez, Fabiola Almeida García, Mario Ernesto Valdés Tresanco, Sandra del Valle Peláiz, Daniel Ojeda del Sol, Talía Frómeta Fuentes, Thalía Acén Ravelo and Belinda Sánchez Ramírez (2023) Mammalian aminopeptidase A: biochemical characteristics, physiological roles and physiopathological implications. Pure and applied Chemistry. https://doi.org/10.1515/pac-2023-0301
5. Fabiola Almeida García, Laura Rivera Méndez, Talía Frómeta Fuentes, Thalía Acén Ravelo,Roberto Alonso Bosch, Wilmer H. Perera, Yarini Arrebola Sánchez, Gretchen Bergado, Belinda Sánchez Ramírez, Jean-Louis Charli and Isel Pascual Alonso* (2023) Bufotalin inhibits porcine kidney cortex aminopeptidase N and is cytotoxic to APN+ tumor cells. Pure and applied chemistry. https://doi.org/10.1515/pac-2023-0214
6. Yarini Arrebola Sánchez, Fabiola Almeida García, Daniel Ojeda del Sol,Mario E. Valdés-Tresanco, Carlos David Ortiz, Belinda Sánchez Ramírez, and Isel Pascual Alonso* (2023) Dipeptidyl peptidase IV: a multifunctional enzyme with implications in several pathologies including cancer. Physical Medicine Reviews. 1-56. https://doi.org/10.1515/psr-2022-0288
7. PascualAlonso I*, Valiente PA, Valdés-Tresanco ME, Arrebola Y, García FA, Díaz L, García G, Guirola O, Pastor D, Bergado G, Sánchez B, Charli J.L. Discovery of tight-binding competitive inhibitors of dipeptidyl peptidase IV. International Journal of Biological Macromolecules. 2022 Jan 31;196:120-30. https://doi.org/10.1016/j.ijbiomac.2021.12.056.
8. Pascual Alonso I*, García G, Díaz L, Arrebola Y, Méndez LR, García FA, Pacheco MC, Sánchez B, Charli JL. Effect of non-competitive inhibitors of aminopeptidase N on viability of human and murine tumor cells. Pure and Applied Chemistry. 2021 Oct 1;93(10):1161-70. https://doi.org/10.1515/pac-2020-1010 .
9. Méndez LR, Arrebola Y, Valdés-Tresanco ME, Díaz-Guevara L, Bergado G, Sánchez B, Charli JL, Pascual Alonso I*. Bestatin and bacitracin inhibit porcine kidney cortex dipeptidyl peptidase IV activity and reduce human melanoma MeWo cell viability. International Journal of Biological Macromolecules. 2020 Dec 1;164:2944-52.https://doi.org/10.1016/j.ijbiomac.2020.08.157
10.Pascual Alonso I*, Valiente PA, García G, Valdés-Tresanco ME, Arrebola Y, Díaz L, Bounaadja L, Uribe RM, Pacheco MC, Florent I, Charli JL. Discovery of novel non-competitive inhibitors of mammalian neutral M1 aminopeptidase (APN). Biochimie. 2017 Nov 1;142:216-25.https://doi.org/10.1016/j.biochi.2017.09.015