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About me

Ms. Karen León Arcia is a Cuban biochemist and neuroscientist with over 18 years of research experience in molecular neuroscience. She holds a Master's in Neurosciences and is currently pursuing a Ph.D. at the National Autonomous University of Mexico (UNAM).
Previously, she served as Head of the Molecular Genetics Department and Principal Investigator at the Cuban Neuroscience Center for more than a decade. Her research is highly focused on neurodegenerative diseases, particularly the development of immunotherapies and vaccine candidates for Alzheimer's disease, evidenced by her leadership on several funded projects and a key patent for a multi-target chimeric antigen.
Ms. León Arcia has a strong publication record in international journals, covering areas from Alzheimer's disease and Parkinson's to spinocerebellar ataxia. She is an active member of scientific organizations, including the Cuban Academy of Sciences, and has contributed to the scientific community through teaching, student supervision, and peer review.

Ms. Karen León Arcia is a Cuban biochemist and molecular neuroscientist with over 18 years of experience dedicated to neurodegenerative disease research, focusing on immunotherapy development for Alzheimer’s disease. She is currently a Ph.D. candidate in Biological Sciences at the Institute of Neurobiology, National Autonomous University of Mexico (UNAM), building on extensive scientific leadership in Cuba.
Before her doctoral studies, Ms. León Arcia was Head of the Molecular Genetics Department and Principal Investigator at the Cuban Center for Neuroscience (CNEURO) for more than 10 years. She led research teams and managed national grants, notably developing a patented multi-target chimeric antigen designed to elicit immune responses against both amyloid-beta and tau proteins in Alzheimer’s immunotherapy.
Her scholarly contributions include over 25 peer-reviewed articles published in journals such as Vaccine, Movement Disorders, The Cerebellum, and Frontiers in Aging Neuroscience. She has also co-authored books and holds patents related to molecular biology methodologies, including pulsed-field gel electrophoresis.
Committed to mentoring, Ms. León Arcia supervises undergraduate and master’s theses and teaches postgraduate courses. She has been honored with the Abel Santamaría Medal by the Cuban Council of State and maintains active memberships in the Cuban Academy of Sciences and the DOHaD Cuban Research Group. Her engagement with OWSD highlights her dedication to empowering women scientists in developing countries.
Key Research Areas: Alzheimer’s Disease Immunotherapy; Neurodegenerative Diseases (Parkinson’s, Spinocerebellar Ataxias); Molecular Biomarkers; Recombinant Protein Engineering; Molecular Genetics and Microbiology
Education:
Ph.D. Candidate, Biological Sciences | National Autonomous University of Mexico (UNAM) | 2024–Present
M.Sc. in Neurosciences, Cellular and Molecular Neurobiology | National Center for Scientific Research (CNIC), Cuba | 2009
B.Sc. in Biochemistry | University of Havana, Cuba | 2006
Selected Affiliations:
Full Member, OWSD | 2017–Present
Junior Associate, Cuban Academy of Sciences (Natural Sciences) | 2024–2029
Member, Scientific Committee, Cuban Neuroscience Center | 2016–2024
Contact
Email: klarci@gmail.com
ORCID: https://orcid.org/0000-0001-5143-1642

Degrees:

2009
Master     Structural, Cell and Molecular Biology
Specialized in Cellular and Molecular Neurobiology

Publications resulting from Research
Karen León Arcia, Heidi Quintero Alvarez , Laura María Pantoja-Echevarría, Yainelis Garrido Nicot, (2022) A single-container procedure for multiple genomic DNA samples preparation for pulsed field gel electrophoresis, Journal of Microbiological Methods 195 (2022) 106453. https://doi.org/10.1016/j.mimet.2022.106453. (Refereed article)
Anette Hardy-Sosa, Karen León-Arcia, Jorge J. Llibre-Guerra, Jorge Berlanga-Acosta, Saiyet de la C. Baez, Gerardo Guillen-Nieto and Pedro A. Valdes-Sosa (2022) Diagnostic Accuracy of Blood-Based Biomarker Panels: A Systematic Review, Front. Aging Neurosci., 11 March 2022, https://doi.org/10.3389/fnagi.2022.683689. (Refereed article)
Yaimeé Vázquez-Mojena, Karen León-Arcia, Yanetza González-Zaldivar, Roberto Rodríguez-Labrada, Luis Velázquez-Pérez (2021) Gene therapy for Polyglutamine Spinocerebellar Ataxias: Advances, Challenges and Perspectives, Movement Disorder, DOI:10.1002/mds.28819. (Refereed article)
Heidi Quintero Alvarez, Karen León Arcia (2022) Standard protocol for typing Pasteurella multocida by pulsed field electrophoresis in minigels, Rev. CENIC Cienc. Biol.; Vol. 53. (1): 069-079. Año. 2022. e-ISSN: 2221-2450
Karen León-Arcia (2015) Two-dimensional pulsed field minigel electrophoresis for the Cryptococcus neoformans chromosomes characterization: bioinformatic procedure. CENIC Journal/Biological Sciences, 46(2): 119-130. (Refereed article)
Yenner Sánchez-Enamorado, Osney Leiva-Peláez, María Belsis Cordero-Ramírez, Magdalena Oliva-López, Karen León-Arcia (2015) Molecular characterization of Pasteurella multocida strains isolated from catle. VacciMonitor, 24(2):79-85. (Refereed article)
Yainelis Garrido-Nicot, Lilia López-Cánovas, Evelio González-Dalmau, David Higginson-Clark, Karen León-Arcia, Ana María Riverón-Rojas (2014) A mathematical model describing the migration of linear DNA molecules in Transverse Pulsed Field Gel Electrophoresis. CENIC Journal/Biological Sciences, 45(3): 179-189. (Refereed article)
Karen León, Ana María Riverón, Oscar Arencibia, Yenis Santamaría, Lilia López‐Cánovas (2013) Two‐Dimensional Pulsed Field Minigel Electrophoresis with High Throughput Sample Format. Journal of Food Safety, 33:215-221. (Refereed article)
Yilian M. Santos, Karen León, Lilia López, and Ana María Riverón (2013) System for image processing of DNA band patterns obtained by Pulsed Field Gel Electrophoresis. J. Folgueras Méndez et al. (Eds.): CLAIB 2011, IFMBE Proceedings, 33: 85–88, 2013. (Refereed article)
Karen León, Ana M Riverón, Oscar Arencibia, Lilia López-Cánovas (2011) Zinc-imidazole negative staining of chromosomal-sized DNA molecules. Analytical Biochemistry, 402(1):96-8. (Refereed article)

From Experimental Neuroscience to Translational Medicine
2025
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Conferences about advanced research in Neuroscience
2025
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Conferences about advanced research in Neuroscience
2025
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NC-ISO 9001:2015 Quality Management System
2025
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Process and Functions for an effective management
2025
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IX Workshop of Cuban Microbial Collection and other biological materials
2025
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LABIOFAM International Congress
2025
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VIII Cuban Congress of Microbiology and Parasitology
2025
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Havana Biotechnology 2014
2025
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First Meeting of the Iberoamerican Network for Epidemiological Surveillance
2025
icon-pin-location Mexico
The 16th International Symposium on Capillary Electroseparation Techniques
2025
icon-pin-location Italy
4th Cuban Congress of Clinical Neurophysiology
2025
icon-pin-location Havana