Ms Pearl Ntshonga

Pearl Ntshonga is a Medical Laboratory Scientist, UB Foundation Scholar, and SANTHE PhD Fellow at the University of Botswana.

Her previous research centred on understanding resistance mechanisms, particularly the role of disinfectant resistance genes such as qacE and qacEΔ1 in organisms including Klebsiella pneumoniae and Enterobacter species. Through this work, she has contributed to advancing knowledge on the intersection between biocide resistance, infection prevention and control (IPC), and antimicrobial resistance in low- and middle-income settings, co-authored five peer-reviewed publications in the field of AMR, reflecting her growing contribution to scientific research and evidence generation in global health. Her previous work aligned with One Health and public health priorities, particularly in strengthening antimicrobial stewardship and informing policy-relevant interventions.

Currently, her research has transitioned into HIV cure science, where she is investigating the dynamics of viral reservoirs, immune activation, and inflammation in individuals on antiretroviral therapy. Her work explores how intermittent viraemia and ongoing viral transcription may influence reservoir persistence and disease outcomes, with the aim of contributing to strategies for long-term remission and cure. With combined expertise in laboratory science and molecular techniques, her long-term goal is to bridge the gap between research, policy, and implementation in global health, particularly in the African context.