Full Member
Sheila Villa
Membership since:
2025
Field of activity:
Degrees:
2018
Doctorate Medical and Health Sciences incl Neurosciences
Neurobiology, Regenerative medicine
Publications resulting from Research
1. Villa-Cedillo SA, Acosta-Espinoza EJ, Soto-Domínguez A, Rodríguez-Rocha H, Montes-de-Oca-Saucedo CR, García-García A, Loera-Arias MJ, Ríos-Vazquez CS, Sánchez-Torres G, Valdés J, Saucedo-Cárdenas O. (2025) Antioxidant PRDX3 gene therapy protects brain cells and prevents neurodegeneration in an animal model of Parkinson's disease. Neuropeptides. 110:102494. doi: 10.1016/j.npep.2024.102494.
2. De-Leon-Covarrubias UE, Perez-Trujillo JJ, Villa-Cedillo SA, Martinez-Perez AG, Montes-de-Oca-Saucedo CR, Loera-Arias MJ, Garcia-Garcia A, Saucedo-Cardenas O, Montes-de-Oca-Luna R. Metabolites. (2024) Unlocking the Potential: Caloric Restriction, Caloric Restriction Mimetics, and Their Impact on Cancer Prevention and Treatment. 30;14(8):418. doi: 10.3390/metabo14080418.
3. Pioquinto-Avila E, González-Cruz AO, Solís-Estrada J, Hernández-Juarez J, Balderas-Rentería I, Villa-Cedillo SA, Pérez-Trujillo JJ, Arredondo-Espinoza E. Anticancer Activity of HER2-targeting CPP-PTEN-THP Chimeric Proteins. Anticancer Res. 44(6):2567-2575. doi: 10.21873/anticanres.17062.
4. Martinez-Perez AG, Garza-Morales R, Loera-Arias MJ, Villa-Cedillo SA, Garcia-Garcia A, Rodriguez-Rocha H, Flores-Maldonado OE, Valdes J, Perez-Trujillo JJ, Saucedo-Cardenas O. (2024) Long-term antigen-specific immune response by an oncolytic adenovirus encoding SP-SA-E7-4-1BBL in HPV-16 cancer model. Mol Biol Rep. 9;51(1):408. doi: 10.1007/s11033-024-09303-0.
5. Villa-Cedillo SA, Matta-Yee-Chig D, Soto-Domínguez A, Rodríguez-Rocha H, García-García A, Montes-de-Oca-Saucedo CR, Loera-Arias MJ, Valdés J, Saucedo-Cárdenas O. (2023) CDNF overexpression prevents motor-cognitive dysfunction by intrastriatal CPP-based delivery system in a Parkinson's disease animal model. Neuropeptides. 102:102385. doi: 10.1016/j.npep.2023.102385.
6. Soto-Domínguez A, Salas-Treviño D, Guillén-Meléndez GA, Castillo-Velázquez U, Ballesteros-Elizondo RG, Montes-de-Oca-Saucedo CR, Villa-Cedillo SA, Morales-Ávalos R, Rodríguez-Tovar LE, Montes-de-Oca-Luna R, Saucedo-Cárdenas O. (2023) Histopathological, ultrastructural, and biochemical traits of apoptosis induced by peroxisomicine A1 (toxin T-514) from Karwinskia parvifolia in kidney and lung. Toxicon X. Dec 22;17:100148. doi: 10.1016/j.toxcx.2022.100148. eCollection 2023 Mar.
7. Soto-Domínguez A, Salas-Treviño D, Guillén-Meléndez GA, Castillo-Velázquez U, Ballesteros-Elizondo RG, Montes-de-Oca-Saucedo CR, Villa-Cedillo SA, Morales-Ávalos R, Rodríguez-Tovar LE, Montes-de-Oca-Luna R, Saucedo-Cárdenas O. (2022) Histopathological, ultrastructural, and biochemical traits of apoptosis induced by peroxisomicine A1 (toxin T-514) from Karwinskia parvifolia in kidney and lung. Toxicon X. doi: 10.1016/j.toxcx.2022.100148.
8. Guillén-Meléndez GA, Soto-Domínguez A, Loera-Arias MJ, Castillo-Velázquez U, Villa-Cedillo SA, Piña-Mendoza EI, Estrada-Castillón E, Chávez-Montes A, González-Alcocer A, Becerra-Verdín EM, Castañeda-Martínez A, Pérez-Hernández RA, Salas-Treviño D. (2022). Effect of methanolic extract of Mimosa malacophylla A.Gray in vero and HEK-293 cell lines, and in the morphology of kidney and bladder of rats with induced urolithiasis. J Ethnopharmacol. doi: 10.1016/j.jep.2022.115552.
9. Guillén-Meléndez GA, Villa-Cedillo SA, Pérez-Hernández RA, Castillo-Velázquez U, Salas-Treviño D, Saucedo-Cárdenas O, Montes-de-Oca-Luna R, Gómez-Tristán CA, Garza-Arredondo AJ, Zamora-Ávila DE, de Jesús Loera-Arias M, Soto-Domínguez A. (2021). Cytotoxic Effect In Vitro of Acalypha monostachya Extracts over Human Tumor Cell Lines. Plants (Basel). doi: 10.3390/plants10112326.
10. Villa-Cedillo SA, Soto-Domínguez A, Rodríguez-Rocha H, García-García A, de Jesús Loera-Arias M, Rivera-Chávez LF, Acosta-Espinoza EJ, Valdés J, Zavala-Flores LM, Montes-de-Oca-Luna R, Saucedo-Cárdenas O. (2019). The mRVG-9R peptide as a potential therapeutic vector to the central nervous system cells. Cell Biol Int. doi: 10.1002/cbin.11161.
11. Villa-Cedillo SA, Nava-Hernández MP, Soto-Domínguez A, Hernández-Ibarra JA, Perez-Trujillo JJ, Saucedo-Cárdenas O. (2019). Neurodegeneration, demyelination, and astrogliosis in rat spinal cord by chronic lead treatment. Cell Biol Int. doi: 10.1002/cbin.11147.
12. Soto-Domínguez A, Ballesteros-Elizondo RG, Santoyo-Pérez ME, Rodríguez-Rocha H, García-Garza R, Nava-Hernández MP, Villa-Cedillo SA, Montes-de-Oca-Luna R, Saucedo-Cárdenas O (2018). Peroxisomicine A1 (toxin T-514) induces cell death of hepatocytes in vivo by triggering the intrinsic apoptotic pathway. Toxicon. DOI: 10.1016/j.toxicon.2018.09.010
13. Villa-Cedillo SA, Rodríguez-Rocha H, Zavala-Flores LM, Montes-de-Oca-Luna R, García-García A, Loera-Arias MJ, Saucedo-Cárdenas O (2017). Asn194Lys mutation in RVG29 peptide increases GFP transgene delivery by endocytosis to neuroblastoma and astrocyte cells. Journal of Pharmacy and Pharmacology. DOI: 10.1111/jphp.12766.
14. Ramos-Treviño, J, Bassol-Mayagoitia, S, Ruiz-Flores, P, Espino-Silva, PK, Saucedo-Cárdenas, O, Villa-Cedillo, SA, Nava-Hernández, MP (2017). In vitro evaluation of damage by heavy metals in tight and gap junctions of sertoli cells. DNA and Cell Biology. doi: 10.1089/dna.2017.3839.
15. Villa-Cedillo SA, Saucedo-Cárdenas O (2017). Gene therapy with neurotrophic factors for neurodegenerative diseases. Revista Mexicana de Ciencias Farmacéuticas. https://www.redalyc.org/pdf/579/57956616002.pdf.
16. Martínez-Romero, A., Villa-Cedillo, SA., Bustamante-Gómez, JB., Ortega-Sánchez, JL., García-Luján, C., Alba-Romero, JJ. (2009). Specific detection of anti hiv-1 and anti hiv-2 antibodies by antigens with improved immunoreactivity. Revista Chapingo Serie Zonas Aridas. ISSN: 0186-3131 2009 8:223-227.
2. De-Leon-Covarrubias UE, Perez-Trujillo JJ, Villa-Cedillo SA, Martinez-Perez AG, Montes-de-Oca-Saucedo CR, Loera-Arias MJ, Garcia-Garcia A, Saucedo-Cardenas O, Montes-de-Oca-Luna R. Metabolites. (2024) Unlocking the Potential: Caloric Restriction, Caloric Restriction Mimetics, and Their Impact on Cancer Prevention and Treatment. 30;14(8):418. doi: 10.3390/metabo14080418.
3. Pioquinto-Avila E, González-Cruz AO, Solís-Estrada J, Hernández-Juarez J, Balderas-Rentería I, Villa-Cedillo SA, Pérez-Trujillo JJ, Arredondo-Espinoza E. Anticancer Activity of HER2-targeting CPP-PTEN-THP Chimeric Proteins. Anticancer Res. 44(6):2567-2575. doi: 10.21873/anticanres.17062.
4. Martinez-Perez AG, Garza-Morales R, Loera-Arias MJ, Villa-Cedillo SA, Garcia-Garcia A, Rodriguez-Rocha H, Flores-Maldonado OE, Valdes J, Perez-Trujillo JJ, Saucedo-Cardenas O. (2024) Long-term antigen-specific immune response by an oncolytic adenovirus encoding SP-SA-E7-4-1BBL in HPV-16 cancer model. Mol Biol Rep. 9;51(1):408. doi: 10.1007/s11033-024-09303-0.
5. Villa-Cedillo SA, Matta-Yee-Chig D, Soto-Domínguez A, Rodríguez-Rocha H, García-García A, Montes-de-Oca-Saucedo CR, Loera-Arias MJ, Valdés J, Saucedo-Cárdenas O. (2023) CDNF overexpression prevents motor-cognitive dysfunction by intrastriatal CPP-based delivery system in a Parkinson's disease animal model. Neuropeptides. 102:102385. doi: 10.1016/j.npep.2023.102385.
6. Soto-Domínguez A, Salas-Treviño D, Guillén-Meléndez GA, Castillo-Velázquez U, Ballesteros-Elizondo RG, Montes-de-Oca-Saucedo CR, Villa-Cedillo SA, Morales-Ávalos R, Rodríguez-Tovar LE, Montes-de-Oca-Luna R, Saucedo-Cárdenas O. (2023) Histopathological, ultrastructural, and biochemical traits of apoptosis induced by peroxisomicine A1 (toxin T-514) from Karwinskia parvifolia in kidney and lung. Toxicon X. Dec 22;17:100148. doi: 10.1016/j.toxcx.2022.100148. eCollection 2023 Mar.
7. Soto-Domínguez A, Salas-Treviño D, Guillén-Meléndez GA, Castillo-Velázquez U, Ballesteros-Elizondo RG, Montes-de-Oca-Saucedo CR, Villa-Cedillo SA, Morales-Ávalos R, Rodríguez-Tovar LE, Montes-de-Oca-Luna R, Saucedo-Cárdenas O. (2022) Histopathological, ultrastructural, and biochemical traits of apoptosis induced by peroxisomicine A1 (toxin T-514) from Karwinskia parvifolia in kidney and lung. Toxicon X. doi: 10.1016/j.toxcx.2022.100148.
8. Guillén-Meléndez GA, Soto-Domínguez A, Loera-Arias MJ, Castillo-Velázquez U, Villa-Cedillo SA, Piña-Mendoza EI, Estrada-Castillón E, Chávez-Montes A, González-Alcocer A, Becerra-Verdín EM, Castañeda-Martínez A, Pérez-Hernández RA, Salas-Treviño D. (2022). Effect of methanolic extract of Mimosa malacophylla A.Gray in vero and HEK-293 cell lines, and in the morphology of kidney and bladder of rats with induced urolithiasis. J Ethnopharmacol. doi: 10.1016/j.jep.2022.115552.
9. Guillén-Meléndez GA, Villa-Cedillo SA, Pérez-Hernández RA, Castillo-Velázquez U, Salas-Treviño D, Saucedo-Cárdenas O, Montes-de-Oca-Luna R, Gómez-Tristán CA, Garza-Arredondo AJ, Zamora-Ávila DE, de Jesús Loera-Arias M, Soto-Domínguez A. (2021). Cytotoxic Effect In Vitro of Acalypha monostachya Extracts over Human Tumor Cell Lines. Plants (Basel). doi: 10.3390/plants10112326.
10. Villa-Cedillo SA, Soto-Domínguez A, Rodríguez-Rocha H, García-García A, de Jesús Loera-Arias M, Rivera-Chávez LF, Acosta-Espinoza EJ, Valdés J, Zavala-Flores LM, Montes-de-Oca-Luna R, Saucedo-Cárdenas O. (2019). The mRVG-9R peptide as a potential therapeutic vector to the central nervous system cells. Cell Biol Int. doi: 10.1002/cbin.11161.
11. Villa-Cedillo SA, Nava-Hernández MP, Soto-Domínguez A, Hernández-Ibarra JA, Perez-Trujillo JJ, Saucedo-Cárdenas O. (2019). Neurodegeneration, demyelination, and astrogliosis in rat spinal cord by chronic lead treatment. Cell Biol Int. doi: 10.1002/cbin.11147.
12. Soto-Domínguez A, Ballesteros-Elizondo RG, Santoyo-Pérez ME, Rodríguez-Rocha H, García-Garza R, Nava-Hernández MP, Villa-Cedillo SA, Montes-de-Oca-Luna R, Saucedo-Cárdenas O (2018). Peroxisomicine A1 (toxin T-514) induces cell death of hepatocytes in vivo by triggering the intrinsic apoptotic pathway. Toxicon. DOI: 10.1016/j.toxicon.2018.09.010
13. Villa-Cedillo SA, Rodríguez-Rocha H, Zavala-Flores LM, Montes-de-Oca-Luna R, García-García A, Loera-Arias MJ, Saucedo-Cárdenas O (2017). Asn194Lys mutation in RVG29 peptide increases GFP transgene delivery by endocytosis to neuroblastoma and astrocyte cells. Journal of Pharmacy and Pharmacology. DOI: 10.1111/jphp.12766.
14. Ramos-Treviño, J, Bassol-Mayagoitia, S, Ruiz-Flores, P, Espino-Silva, PK, Saucedo-Cárdenas, O, Villa-Cedillo, SA, Nava-Hernández, MP (2017). In vitro evaluation of damage by heavy metals in tight and gap junctions of sertoli cells. DNA and Cell Biology. doi: 10.1089/dna.2017.3839.
15. Villa-Cedillo SA, Saucedo-Cárdenas O (2017). Gene therapy with neurotrophic factors for neurodegenerative diseases. Revista Mexicana de Ciencias Farmacéuticas. https://www.redalyc.org/pdf/579/57956616002.pdf.
16. Martínez-Romero, A., Villa-Cedillo, SA., Bustamante-Gómez, JB., Ortega-Sánchez, JL., García-Luján, C., Alba-Romero, JJ. (2009). Specific detection of anti hiv-1 and anti hiv-2 antibodies by antigens with improved immunoreactivity. Revista Chapingo Serie Zonas Aridas. ISSN: 0186-3131 2009 8:223-227.