Professor Al-Shaimaa Ahmed
About me
Dr. Al-Shaimaa F. Ahmed is a Professor of Pharmacology and Toxicology at the Faculty of Pharmacy, Minia University, Egypt. She earned her PhD in Neuroscience from the University of Calgary, Canada, focusing on hormonal regulation of feeding and energy balance. Her research interests include neuropharmacology, sepsis-induced organ injury, metabolic disorders, and endocrine pharmacology. Dr. Ahmed has published widely in international peer-reviewed journals and serves as a reviewer for many scientific journals. She is the Director of the Training Unit for the mandatory pharmacy internship year at Minia University and has received multiple International Publication Awards recognizing her research contributions. She is also working as a career advisor in the university center for career development.
Professor Al-Shaimaa Faissal Ahmed, PhD, is a distinguished academic and researcher in Pharmacology and Toxicology at the Faculty of Pharmacy, Minia University, Egypt. She currently serves as Professor of Pharmacology and Toxicology and Director of the Training Unit for the Mandatory Pharmacy Training Year, where she leads initiatives to enhance graduates’ employability and professional readiness. She is also actively engaged with the University Center for Career Development (UCCD), a USAID-supported program previously managed by the American University in Cairo, to foster industry-academic partnerships and skill-based training.
Dr. Ahmed obtained her PhD in Neuroscience from the Cumming School of Medicine, University of Calgary, Canada (2009–2014), under the supervision of Professor Keith Sharkey. Her doctoral research explored the “Role of sensory circumventricular organs in the function of hormones affecting feeding and energy balance,” contributing valuable insights to the neuroendocrine regulation of appetite and metabolism. She also holds an MSc in Pharmacology and Toxicology (2008) and a BSc (Honors) in Pharmaceutical Sciences (2003), both from Minia University, Egypt.
Throughout her academic career, Dr. Ahmed has held progressive academic appointments—from Lecturer (2015) to Associate Professor (2020) and Professor (2025)—at Minia University. She has also served as a Visiting Professor at the University of Calgary (2022), maintaining active international collaborations in neuropharmacology and inflammation research.
Her teaching experience spans more than a decade, encompassing undergraduate and postgraduate courses in pharmacology, toxicology, molecular pharmacology, biostatistics, and clinical pharmacology. She has been instrumental in modernizing pharmacology education by incorporating simulated learning, patient counseling modules, and Objective Structured Clinical Examinations (OSCEs) into the curriculum.
Dr. Ahmed’s research portfolio reflects a strong interdisciplinary orientation bridging neuropharmacology, inflammation, endocrinology, and translational medicine. Her studies have elucidated molecular mechanisms in sepsis-induced organ injury, neuroprotection in ischemic stroke, metabolic and hormonal disorders such as PCOS, and cardiovascular pharmacotherapy. She has contributed to numerous national and international research projects funded by the Science and Technology Development Fund (STDF, Egypt) and the Deanship of Scientific Research, Umm Al-Qura University (Saudi Arabia). Her recent collaborative projects include investigations into selective estrogen receptor modulators, TRPM8 channels in sepsis, and SGLT2 inhibitors in metabolic disorders.
Dr. Ahmed has published extensively in peer-reviewed journals including Bioorganic Chemistry, Life Sciences, BMC Cardiovascular Disorders, Clinical and Experimental Pharmacology and Physiology, International Immunopharmacology, and Naunyn-Schmiedeberg’s Archives of Pharmacology. She has co-authored over 40 scientific papers and numerous conference abstracts, and her work has been recognized by multiple International Publication Awards from Minia University (2020–2023).
In addition to her research and teaching, Dr. Ahmed serves as a review editor for Frontiers in Physiology and an active reviewer for leading journals such as Scientific Reports, Clinical Science, Drug Design, Development and Therapy, Expert Review of Clinical Pharmacology, Molecules (MDPI), and Frontiers in Pharmacology. Her academic leadership roles include serving as Assistant Director of the Quality Assurance and Accreditation Unit (2023–2024) and Assistant Program Coordinator for Training Affairs in the Clinical Pharmacy Program since 2018.
Beyond academia, Dr. Ahmed is a strong advocate for youth development and community engagement. She has served as Conference Secretary General for the Minia Pharmacy Scientific Conference, a board member of the Nile International Egyptian School, and a supervisor for the Egyptian Pharmacy Students’ Federation (EPSF-Minia). Internationally, she volunteered as President of the Egyptian Students’ Association in Calgary and as a judge for the Calgary Youth Science Fair, reflecting her commitment to mentoring future scientists.
Dr. Ahmed’s professional recognition includes the Canadian Association of Neuroscience Travel Award (2011) and the Achievers in Medical Science Scholarship from the University of Calgary. Her passion for integrating pharmacological science, education, and global collaboration continues to inspire her students and colleagues alike.
Other Memberships/Affiliations
Degrees:
Al-Kadi A, Anter, A, Abdel Hafez SA, R. Roshdy, ElSayed M, Ahmed, AF. Klotho Modulation by Tempol: A Potential Therapeutic Axis in Sepsis. BMC Cardiovascular diseases (April 2025, accepted article)
Bader Huwaimel, Amr S. Abouzied, Abdul-Hamid Emwas, Al-Shaimaa F. Ahmed, Mohamed K.S. El-Nagar, Hamdoon A. Mohammed, Nader M. Alrashidi, Marwan A. Alrashidi, Rakan E. Alshammari, Abdulelah Y. Albladi, Saad Alqarni, Shaymaa E. Kassab. 2025. Precise structure manipulation of selective estrogen receptor modulators led to first-in-class thiophene-3-benzamide derivatives as potential ER-antagonists without uterotrophic activity. Bioorganic Chemistry, 161:108512,
Al-kadi, A., Anter, A.F., Rofaeil, R.R., Sayed-Ahmed, M.M., Hafez, S.M.N.A. and Ahmed, A.-S.F. 2025. Endothelin System Blockade Extenuates Sepsis-Induced Acute Heart and Kidney Injuries via Modulating ET-1/Klotho/p38-MAPK. Clin Exp Pharmacol Physiol, 52: e70042
Al-Kadi A, Anter, A, R. Roshdy, ElSayed M, Ahmed, AF. 2025. Klotho: A Multifaceted Protector in Sepsis-Induced Organ Damage and a Potential Therapeutic Target. 2025. World J Crit Care Med 14(3): 103458
Elrehany, O. M., Ahmed, A. S. F., Abou-Zied, H. A., Hayallah, A. M., Abdel-Aziz, M., & Nazmy, M. H. 2024. Investigation of anticancer mechanisms of a chalcone/xanthine hybrid in Non-Small Cell Lung Cancer. Bulletin of Pharmaceutical Sciences Assiut University. 47 (2), 1353-1366
Shehata, Alaa H., Aliaa F. Anter, Sara Mohamed Naguib Abdel Hafez, Ahmed RN Ibrahim, Eman S. Kamel, and Al-Shaimaa F. Ahmed. 2024 Pioglitazone ameliorates sepsis-associated encephalopathy through SIRT1 signaling pathway. International Immunopharmacology 139: 112757.
Sarah Sameh Abdel-Hameed, Mahmoud El-Daly, Al-Shaimaa F. Ahmed, Amany A Bekhit, Gehan H Heeba. 2024. Dapoxetine prevents neuronal damage and improves functional outcomes in a model of ischemic stroke through the modulation of inflammation and oxidative stress. Naunyn-Schmiedeberg's Archives of Pharmacology. 397 (1), 253-266
Al-Kadi, A., M. El-Daly, N. F. G. El-Tahawy, O. Fahmi, A. B. Abdel-Naim, M. M. A. Khalifa, and A. F. Ahmed. 2024 Therapeutic potential of ramipril, losartan, and spironolactone against sepsis-associated liver tissue injury induced by cecal ligation and puncture in rats. European Review for Medical & Pharmacological Sciences 28 (5).
VM Pulgar, C Guibert, ASF Ahmed, AJ Trask 2023. Editorial on the Research Topic Model Organisms and Experimental Models: Opportunities and Challenges in Vascular Physiology Research. Frontiers in Physiology 14, 1271220
2023
Shehata, A. H., Anter, A. F., & Ahmed, A.-S. F. 2023. Role of SIRT1 in sepsis-induced encephalopathy: Molecular targets for future therapies. European Journal of Neuroscience, 125.
C. E. Matisz, N. Semenoff, A.-S. F. Ahmed, L. Griffin, L. E. Wallace, P. McNabb, et al. 2022. Acute gut inflammation reduces neural activity and spine maturity in hippocampus but not basolateral amygdala Scientific Reports 2022 Vol. 12 Issue 1
A.-S. F. Ahmed, S. S. Sharkawi, S. S. AbdelHameed, A. M. Bayoumi, R. S. Moussa, N. A. Alhakamy, et al.
2023. Ketogenic diet restores hormonal, apoptotic/proliferative balance and enhances the effect of metformin on a letrozole-induced polycystic ovary model in rats. Life Sciences
E. M. Awad, A.-S. F. Ahmed, M. El-Daly, A. H. Amin, N. F. El-Tahawy, A. Wagdy, M. Hollenberg and A. Taye. 2022 Dihydromyricetin protects against high glucose-induced endothelial dysfunction: Role of HIF-1α/ROR2/NF-κB. Biomedicine & Pharmacotherapy Vol. 153.
O. Bender, I. Celik, R. Dogan, A. Atalay, M. E. Shoman, T. F. Ali, Ahmed A-SF. et al. 2023. Vanillin-Based Indolin-2-one Derivative Bearing a Pyridyl Moiety as a Promising Anti-Breast Cancer Agent via Anti-Estrogenic Activity. ACS omega Vol. 8 Issue 7
A. Anter, A.-S. F. Ahmed, A. W. Kasem, A. Hammad, W. Almalki, S. Abdel Hafez, et al. 2022. The severity of acute kidney and lung injuries induced by cecal ligation and puncture is attenuated by menthol: role of PCNA and apoptotic markers. Frontiers in Medicine
S. R. Senousy, M. El-Daly, A. R. Ibrahim, M. M. A. Khalifa and A.-S. F. Ahmed: Effect of Celecoxib and Infliximab against Multiple Organ Damage Induced by Sepsis in Rats: A Comparative Study. Biomedicines 2022 Vol. 10 Issue 7
Raafat M, Kamel AA, Shehata AH, Ahmed A-SF, Bayoumi A, Moussa RA, Abourehab MA, El-Daly M. 2022. Aescin Protects against Experimental Benign Prostatic Hyperplasia and Preserves Prostate Histomorphology in Rats via Suppression of Inflammatory Cytokines and COX-2. Pharmaceuticals. 15(2):130
Ragab MA, Elagawany M, Daabees H, Ahmed A-SF, Awad EM, Billon C, Elgendy B, Abouzid KA, Kassab SE. 2022. Structure-based design and synthesis of conformationally constrained derivatives of methyl-piperidinopyrazole (MPP) with estrogen receptor (ER) antagonist activity. Bioorganic Chemistry. 119:105554.
Awad E, Ahmed A-SF, El-Daly M, El-Tahawy N, Kasem A, Taye A. 2022. Role of apoptosis and oxidative stress in high glucose-induced endothelial dysfunction in isolated aortic rings. Journal of advanced Biomedical and Pharmaceutical Sciences. 5(1):23-28.
Tawfik AG, Abdelaziz AI, Omran M, Rabie KA, Ahmed A-SF, Abou-Ali A. 2021. Assessment of community pharmacy management towards self-medication requests of tetracyclines for pregnant women: a simulated client study in Upper Egypt. International journal of clinical pharmacy. 43(4):969-979.
Singh D, Gupta S, Verma I, Morsy MA, Nair AB, Ahmed A-SF. 2021. Hidden pharmacological activities of valproic acid: A new insight. Biomedicine & Pharmacotherapy. 142:112021.
Senousy SR, Ahmed A-SF, El-Daly M, Khalifa MA. 2021. Cytokines in sepsis: friend or enemy? Journal of advanced Biomedical and Pharmaceutical Sciences.29-39.
Alzahrani, A., M.E.-S.M. El-Daly, and Ahmed A-SF, A critical review on therapeutic potential of vitamin D mediated suppression of miRNA222 associated metabolic defect in polycystic ovarian syndrome. Critical Reviews™ in Eukaryotic Gene Expression.
Al‐Kadi, El-Daly M, Khalifa MA Ahmed A-SF, Angiotensin aldosterone inhibitors improve survival and ameliorate kidney injury induced by sepsis through suppression of inflammation and apoptosis. Fundamental & Clinical Pharmacology, 2021.
Shehata, A.H., Ahmed A-SF, Bekheit Amany, Heeba G., The impact of single and combined PPAR-α and PPAR-γ activation on the neurological outcomes following cerebral ischemia reperfusion. Life sciences, 2020. 252: p. 117679
Ibrahim, Y.F., Bayoumi A, Mousa R. Ahmed A-SF, Tocilizumab attenuates acute lung and kidney injuries and improves survival in a rat model of sepsis via down-regulation of NF-κB/JNK: a possible role of P-glycoprotein. Inflammopharmacology, 2020. 28(1): p. 215-230.
Ahmed A-SF,, A.M.A.B., Heba M. Eltahir , Sara M.N. Abdel Hafez, Mekky M. Abouzied, Amelioration of Sepsis-Induced Liver and Lung Injury by a Superoxide Dismutase Mimetic; Role of TNF-alpha and Caspase-3. Journal of Advanced Biomedical and Pharmaceutical Sciences, 2020. 3(1).
Al-Kadi, A., Ahmed A-SF, Khalifa MM, El-Daly M, Silymarin protects against sepsis-induced acute liver and kidney injury via anti-inflammatory and antioxidant mechanisms in the rat. Journal of Advanced Biomedical and Pharmaceutical Sciences, 2020. 3: p. 190-197.
Hammad, A.S., Ahmed A-SF, Heeba G, Taye A., Heme oxygenase-1 contributes to the protective effect of resveratrol against endothelial dysfunction in STZ-induced diabetes in rats. Life sciences, 2019. 239: p. 117065
Asmaa, S.A.H., Ahmed A-SF, Heeba G, Taye A, Resveratrol protects against early cardiomyopathic changes-induced by Type-1 diabetes through a heme-oxygenase-1 dependent mechanism. Journal of Advanced Biomedical and Pharmaceutical Sciences, 2019. 2(1): p. 12-18.
Abdelaziz, A.I., Omran M, Rabie KA, Abou-Ali, Ahmed A-SF, Quality of Community Pharmacy Practice in Antibiotic Self-Medication Encounters: A Simulated Patient Study in Upper Egypt. Antibiotics, 2019. 8(2): p. 35.
Abd-Ellah, H.S., M.A.-A., Mai E. Shoman, Eman A.M. Beshr, Tamer S. Kaoud, Ahmed A-SF, New 1, 3, 4-oxadiazole/oxime hybrids: Design, synthesis, anti-inflammatory, COX inhibitory activities and ulcerogenic liability. Bioorganic chemistry, 2017. 74: p. 15-29.
Heba S. Abd-Ellah, M.A.-A., Mai E. Shoman, Eman A.M. Beshr, Tamer S. Kaoud, Ahmed A-SF, Novel 1,3,4-oxadiazole/oxime hybrids: Synthesis, docking studies and investigation of anti-inflammatory, ulcerogenic liability and analgesic activities. Bioorganic chemistry, 2016. 69: p. 48-63.
Ahmed A-SF, Ho W, Ferguson A, Sharkey KA, The subfornical organ: a novel site of action of cholecystokinin. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2014. 306(5): p. R363-R373.
Ahmed A-SF, Role of Sensory Circumventricular Organs in the Function of Hormones Affecting Feeding and Energy Balance. 2014, University of Calgary.
Khalifa, M., Moselhy M., Kasem M, Ahmed A-SF, Evaluation of the effects of rofecoxib and nitric oxide-releasing aspirin on stress-Induced gastric ulcers in rats. Saudi Pharmaceutical J, 2008. 16(3-4): p. 203-213.