Full Member
Julia de Guadalupe Rodríguez Castelán
Membership since:
2025
Field of activity:
About me
Bachelor's degree in Nutrition from the University of Veracruz. Xalapa Region. Master's and Doctorate in Biological Sciences from the Autonomous University of Tlaxcala. Diploma in Renal Nutrition, Cristóbal Colón University, and International Certification in Psychonutrition from the Vive Sano University Institute, Brazil. She was a postdoctoral researcher at the Institute of Neurobiology at the National Autonomous University of Mexico (UNAM). Member of scientific associations such as the Mexican Society of Biochemistry, Mexican Society of Physiological Sciences, Mexican Association of Nutriology, Endocrine Society, and OWSD. Mentor for the British Council's Women Leaders in STEAM, PAUTA, and Mentors for Science programs. Coordinator of scientific education and professional development within AMENAC Veracruz chapter and co-coordinator of communication for OWSD Mexico Chapter. Co-author of 20 JCR scientific articles and 5 book chapters. Currently Postgraduate Coordinator of the Health Sciences Division at Cristóbal Colón University. Independent consultant at Nutria Científica.
Degrees:
2018
Doctorate Biological Systems and Organisms
Publications resulting from Research
1. Luna-Vazquez F, Cruz-Lumbreras R, Rodríguez-Castelán J, Cervantes-Rodríguez M, Rodríguez-Antolín J, Arroyo-Helguera O, Castelán F, Martínez-Gómez M, Cuevas, E. Association between the serum concentration of triiodothyronine with components of metabolic syndrome, cardiovascular risk, and diet in euthyroid post-menopausal women without and with metabolic syndrome. SpringerPlus. 3: 266-74, 2014.
2. Anaya‐Hernández A, Rodríguez‐Castelán J, Nicolás L, Martínez‐Gómez M, Jiménez‐Estrada I, Castelán F, Cuevas E. Hypothyroidism affects differentially the cell size of epithelial cells among oviductal regions of rabbits. Reprod Domest Anim. 50:104-11, 2015.
3. Rodríguez-Castelán J, Nicolás L, Morimoto S, Cuevas E. The Langerhans islet cells of female rabbits are differentially affected by hypothyroidism depending on the islet size. Endocrine. 48: 811-817. 2015.
4. Rodríguez-Castelán J, Martínez-Gómez M, Castelán F, Cuevas E. Hypothyroidism affects vascularization and promotes immune cells infiltration into pancreatic islets of female rabbits. Int J Endocrinol 2015. 8 pages, 2015.
5. Sánchez‐García O, Rodríguez‐Castelán J, Martínez‐Gómez M, Cuevas E, Castelán F. Hypothyroidism modifies morphometry and thyroid‐hormone receptor expression in periurethral muscles of female rabbits. Neurourol Urodyn 35: 895–901, 2016.
6. Rodríguez-Castelán J, Anaya-Hernández A, Méndez-Tepepa M, Martínez-Gómez M, Castelán F, Cuevas-Romero E. Distribution of thyroid hormone and thyrotropin receptors in reproductive tissues of adult female rabbits. Endocr Res 42:59-70, 2017.
7. Rodríguez-Castelán J, Méndez-Tepepa M, Carrillo-Portillo Y, Anaya-Hernández A, Rodríguez-Antolín J, Zambrano E, Castelán F, Cuevas-Romero E. Hypothyroidism reduces the size of ovarian follicles and promotes hypertrophy of periovarian fat with infiltration of macrophages in adult rabbits. Biomed Res Int 2017:3795950, 2017.
8. Rodríguez-Castelán J, Corona-Pérez A, Nicolás-Toledo L, Martínez-Gómez M, Castelán F, Cuevas-Romero E. Hypothyroidism induces a moderate steatohepatitis accompanied by liver regeneration, mast cells infiltration, and changes in the expression of the farnesoid x receptor. Exp Clin Endocrinol 125: 183-90, 2017.
9. Sánchez-García O, López-Juárez R, Rodríguez-Castelán J, Corona-Quintanilla DL, Martínez-Gómez M, Cuevas-Romero E, Castelán F. Hypothyroidism impairs somatovisceral reflexes involved in micturition of female rabbits. Neurourol Urodyn. 37(8): 2406-13. 2018.
10. Rodríguez-Castelán J, Méndez-Tepepa M, Rodríguez-Antolín J, Castelán F, Cuevas-Romero E. Hypothyroidism affects the content of lipids and glycogen, and the PPAR-δ expression in the ovary of rabbits. Reprod Fertil Dev.30(10):1380-7. 2018.
11. Rodríguez-Castelán J, Zepeda-Pérez D. Méndez-Tepepa M, Castillo-Romano M, Espíndola-Lozano M, Anaya-Hernández A, Berbel P, Cuevas-Romero E. Hypothyroidism modifies the uterine lipid levels in pregnant rabbits and affects the fetal size. Endocr Metab Immune Disord Drug Targets. 19: 818-25. 2018.
12. Rodríguez-Castelán J, Del Moral-Morales A, Piña-Medina AG, Zepeda-Pérez D, Castillo-Romano M, Méndez-Tepepa M, Espíndola-Lozano M, Camacho-Arroyo I, Cuevas-Romero E. Hypothyroidism induces uterine hyperplasia and inflammation related to sex hormone receptors expresión in virgin rabbits. Life Sci. 230:111-20. 2019.
13. Peña M, Delgado-Gonzalez E, López-Marín LM, Millán-Chiu BE, Fernández F, Rodriguez-Castelan J, Muñoz-Torres C, Anguiano B, Loske AM, Aceves C. Shock wave application synergizes the antineoplastic effect of molecular iodine supplement in breast cancer xenografts. Ultrasound in Medicine and Biology, 46(3):649-59. 2020.
14. Méndez-Tepepa M, Zepeda-Pérez D, Espíndola-Lozano M, Rodríguez-Castelán J, Arroyo-Helguera O, Pacheco P, Nicolás-Toledo L, Cuevas Romero-E. Hypothyroidism modifies differentially the content of lipids and glycogen, lipid receptors, and intraepitelial lymphocytes among oviductal regions of rabbits. Reprod Biol, S1642-431X(19)30344-4. 2020.
15. Sánchez-Tusie-A, Montes de Oca C, Rodríguez-Castelán J, Delgado-González E, Ortiz Z, Álvarez L, Zarco C, Aceves C, Anguiano B. A rise in T3/T4 ratio reduces the growth of prostate tumors in a murine model. J Endocrinol, 247(3):225-38. 2020.
16. Mendieta I, Rodríguez-Gómez G, Rueda-Zarazúa B, Rodríguez-Castelán J, Álvarez-León W, Delgado-González E, Anguiano B, Vázquez-Martínez O, Díaz-Muñoz M, Aceves C. Molecular iodine synergized and sensitized neuroblastoma cells to the antineoplastic effect of ATRA. Endocr Relat Cancer, 27(12):699-710. 2020.
17. Rodríguez-Castelán, J., Zepeda-Pérez, D., Rojas-Juárez, R., Aceves, C., Castelán, F., & Cuevas-Romero, E. (2022). Effects of hypothyroidism on the female pancreas involve the regulation of estrogen receptors. Steroids, 181, 108996.
18. Rodríguez-Castelán, J., Delgado-González, E., Varela-Floriano, V., Anguiano, B., & Aceves, C. (2022). Molecular Iodine Supplement Prevents Streptozotocin-Induced Pancreatic Alterations in Mice. Nutrients, 14(3), 715.
19. Rojas-Juárez R, Cuatecontzi-Fuentes I, Méndez-Tepepa M., Rodríguez-Castelán J, Cruz-Lumbreras R, Rodríguez-Antolín J, Arroyo-Helguera OE, Cuevas-Romero E. (2022). Hypothyroidism affects de novo synthesis of cholesterol and lipids signaling in the pancreas of female rabbits. Steroids, 181, 108996.
20. Varela-Floriano, V.; Rojas-López, M.; Méndez, S.S.; Luna-Vázquez, F.; Rodríguez-Castelán, J. Diet-Induced Metabolic Syndrome Altered Bladder Urothelium in Adult Female Rats. Biol. Life Sci. Forum 2023, 29, 18.
21. Rojas-Juárez, R., Rodríguez-Castelán, J., Cuatecontzi-Fuentes, I., Mendez-Tepepa, M., Cruz-Lumbreras, R., Rodríguez-Antolín, J., Arroyo-Helguera, O. E., & Cuevas-Romero, E. (2025). Pancreatic inflammation induced by hypothyroidism in female rabbits is associated with cholesterol accumulation and a reduced expression of CYP51A1, FXRβ, and PPARβ/δ. Anatomical record (Hoboken, N.J. : 2007), 308(5), 1517–1528.
2. Anaya‐Hernández A, Rodríguez‐Castelán J, Nicolás L, Martínez‐Gómez M, Jiménez‐Estrada I, Castelán F, Cuevas E. Hypothyroidism affects differentially the cell size of epithelial cells among oviductal regions of rabbits. Reprod Domest Anim. 50:104-11, 2015.
3. Rodríguez-Castelán J, Nicolás L, Morimoto S, Cuevas E. The Langerhans islet cells of female rabbits are differentially affected by hypothyroidism depending on the islet size. Endocrine. 48: 811-817. 2015.
4. Rodríguez-Castelán J, Martínez-Gómez M, Castelán F, Cuevas E. Hypothyroidism affects vascularization and promotes immune cells infiltration into pancreatic islets of female rabbits. Int J Endocrinol 2015. 8 pages, 2015.
5. Sánchez‐García O, Rodríguez‐Castelán J, Martínez‐Gómez M, Cuevas E, Castelán F. Hypothyroidism modifies morphometry and thyroid‐hormone receptor expression in periurethral muscles of female rabbits. Neurourol Urodyn 35: 895–901, 2016.
6. Rodríguez-Castelán J, Anaya-Hernández A, Méndez-Tepepa M, Martínez-Gómez M, Castelán F, Cuevas-Romero E. Distribution of thyroid hormone and thyrotropin receptors in reproductive tissues of adult female rabbits. Endocr Res 42:59-70, 2017.
7. Rodríguez-Castelán J, Méndez-Tepepa M, Carrillo-Portillo Y, Anaya-Hernández A, Rodríguez-Antolín J, Zambrano E, Castelán F, Cuevas-Romero E. Hypothyroidism reduces the size of ovarian follicles and promotes hypertrophy of periovarian fat with infiltration of macrophages in adult rabbits. Biomed Res Int 2017:3795950, 2017.
8. Rodríguez-Castelán J, Corona-Pérez A, Nicolás-Toledo L, Martínez-Gómez M, Castelán F, Cuevas-Romero E. Hypothyroidism induces a moderate steatohepatitis accompanied by liver regeneration, mast cells infiltration, and changes in the expression of the farnesoid x receptor. Exp Clin Endocrinol 125: 183-90, 2017.
9. Sánchez-García O, López-Juárez R, Rodríguez-Castelán J, Corona-Quintanilla DL, Martínez-Gómez M, Cuevas-Romero E, Castelán F. Hypothyroidism impairs somatovisceral reflexes involved in micturition of female rabbits. Neurourol Urodyn. 37(8): 2406-13. 2018.
10. Rodríguez-Castelán J, Méndez-Tepepa M, Rodríguez-Antolín J, Castelán F, Cuevas-Romero E. Hypothyroidism affects the content of lipids and glycogen, and the PPAR-δ expression in the ovary of rabbits. Reprod Fertil Dev.30(10):1380-7. 2018.
11. Rodríguez-Castelán J, Zepeda-Pérez D. Méndez-Tepepa M, Castillo-Romano M, Espíndola-Lozano M, Anaya-Hernández A, Berbel P, Cuevas-Romero E. Hypothyroidism modifies the uterine lipid levels in pregnant rabbits and affects the fetal size. Endocr Metab Immune Disord Drug Targets. 19: 818-25. 2018.
12. Rodríguez-Castelán J, Del Moral-Morales A, Piña-Medina AG, Zepeda-Pérez D, Castillo-Romano M, Méndez-Tepepa M, Espíndola-Lozano M, Camacho-Arroyo I, Cuevas-Romero E. Hypothyroidism induces uterine hyperplasia and inflammation related to sex hormone receptors expresión in virgin rabbits. Life Sci. 230:111-20. 2019.
13. Peña M, Delgado-Gonzalez E, López-Marín LM, Millán-Chiu BE, Fernández F, Rodriguez-Castelan J, Muñoz-Torres C, Anguiano B, Loske AM, Aceves C. Shock wave application synergizes the antineoplastic effect of molecular iodine supplement in breast cancer xenografts. Ultrasound in Medicine and Biology, 46(3):649-59. 2020.
14. Méndez-Tepepa M, Zepeda-Pérez D, Espíndola-Lozano M, Rodríguez-Castelán J, Arroyo-Helguera O, Pacheco P, Nicolás-Toledo L, Cuevas Romero-E. Hypothyroidism modifies differentially the content of lipids and glycogen, lipid receptors, and intraepitelial lymphocytes among oviductal regions of rabbits. Reprod Biol, S1642-431X(19)30344-4. 2020.
15. Sánchez-Tusie-A, Montes de Oca C, Rodríguez-Castelán J, Delgado-González E, Ortiz Z, Álvarez L, Zarco C, Aceves C, Anguiano B. A rise in T3/T4 ratio reduces the growth of prostate tumors in a murine model. J Endocrinol, 247(3):225-38. 2020.
16. Mendieta I, Rodríguez-Gómez G, Rueda-Zarazúa B, Rodríguez-Castelán J, Álvarez-León W, Delgado-González E, Anguiano B, Vázquez-Martínez O, Díaz-Muñoz M, Aceves C. Molecular iodine synergized and sensitized neuroblastoma cells to the antineoplastic effect of ATRA. Endocr Relat Cancer, 27(12):699-710. 2020.
17. Rodríguez-Castelán, J., Zepeda-Pérez, D., Rojas-Juárez, R., Aceves, C., Castelán, F., & Cuevas-Romero, E. (2022). Effects of hypothyroidism on the female pancreas involve the regulation of estrogen receptors. Steroids, 181, 108996.
18. Rodríguez-Castelán, J., Delgado-González, E., Varela-Floriano, V., Anguiano, B., & Aceves, C. (2022). Molecular Iodine Supplement Prevents Streptozotocin-Induced Pancreatic Alterations in Mice. Nutrients, 14(3), 715.
19. Rojas-Juárez R, Cuatecontzi-Fuentes I, Méndez-Tepepa M., Rodríguez-Castelán J, Cruz-Lumbreras R, Rodríguez-Antolín J, Arroyo-Helguera OE, Cuevas-Romero E. (2022). Hypothyroidism affects de novo synthesis of cholesterol and lipids signaling in the pancreas of female rabbits. Steroids, 181, 108996.
20. Varela-Floriano, V.; Rojas-López, M.; Méndez, S.S.; Luna-Vázquez, F.; Rodríguez-Castelán, J. Diet-Induced Metabolic Syndrome Altered Bladder Urothelium in Adult Female Rats. Biol. Life Sci. Forum 2023, 29, 18.
21. Rojas-Juárez, R., Rodríguez-Castelán, J., Cuatecontzi-Fuentes, I., Mendez-Tepepa, M., Cruz-Lumbreras, R., Rodríguez-Antolín, J., Arroyo-Helguera, O. E., & Cuevas-Romero, E. (2025). Pancreatic inflammation induced by hypothyroidism in female rabbits is associated with cholesterol accumulation and a reduced expression of CYP51A1, FXRβ, and PPARβ/δ. Anatomical record (Hoboken, N.J. : 2007), 308(5), 1517–1528.