Ifeoma Felicia Chukwuma

Chukwuma, I. F., Apeh, V. O., Nworah, F. N., Ezeanyika, L. U. S., Ogugua, V.N., Adegboyega, A.E. and Ogugofor, M.O. (2024). Deciphering the therapeutic actions of Brenania brieyi (Rubiaceae) fractions on oxidoinflammatory anomalies. International Journal of Secondary Metabolite, 11(4):633-645. https://doi.org/10.21448/ijsm.1434379.
• Ezeorba, T.P.C., Ezugwu, A.L., Chukwuma, I.F., Anaduaka, E.G., Udenigwe, C.C. (2024). Health-promoting properties of bioactive proteins and peptides of garlic (Allium sativum), Food Chemistry, 435 (1): 137632. https://doi.org/10.1016/j.foodchem.2023.137632.
• Idoko, N.D., Chukwuma, I.F., Nworah, F.N., Mba, S.E., Joshua, P.E., Nwodo,O.F.C, Abusudah, W.F., Almohmadi, N.H., and de Waard, M. (2024). Immunomodulatory effects of epiphytic Loranthus micranthus leaf extracts collected from two host plants: Psidium guajava and Parkia biglobosa. BMC Complementary Medicine and Therapies (2024) 24:7 https://doi.org/10.1186/s12906-023-04282-4.
• Chukwuma, I.F., Ossai, E.C., Nworah, F.N., Apeh, V.O., Abiaziem, E.O., Iheagwam, F.N., Skendrović, H., Szymon Juchniewicz, S., Leicht, K., Okpala, C.O.R., and Korzeniowska, M. (2024). Changes in nutritional, health benefits, and pharmaceutical potential of raw and roasted tropical almond (Terminalia catappa Linn.) nuts from Nigeria. PLoS ONE 19(1): e0287840. https:// doi.org/10.1371/journal.pone.0287840.
• Chukwuma, I. F., Nweze, E. J., Nworah, F. N., Apeh, V. O., & Ezeorba, T. P. C. (2024). Concentration and Risk assessment analysis of polycyclic aromatic hydrocarbons associated with consuming Procambarus Clarkii (Cray fish) in Nigeria. Research and Innovation in Food Science and Technology, 13(2), 101-108. https://doi.org/10.22101/JRIFST.2023.391567.1449
• Apeh, V.O., Adegboyega, A.E., Chukwuma, I.F., Ugwah-Oguejiofor, C.J., Aja, P.M., Ofeimun, J.O., Ale, B.A., G.I., Ebenyi,L.N., Iwaloye, O., Ejembi, S.A., Ezugworie, F.N., Johnson, T.O. (2023). An in silico study of bioactive compounds of Annona muricata in the design of ani-prostate cancer agent: MM/GBSA, pharmacophore modeling and ADMET parameters, Informatics in Medicine Unlocked, 43: 101377. https://doi.org/10.1016/j.imu.2023.101377.
• Yusuf, A.J., Adegboyega, A.E., Yakubu, A.H., Johnson, G.I., Asomadu, R.O., Adeduro, M.N., Chukwuma, I.F., Ugwah-Oguejiofor, C.J., Okoh, O.S., Johnson, T.O. (2023). Exploring Scutellaria baicalensis bioactives as EGFR tyrosine kinase inhibitors: Cheminformatics and molecular docking studies, Informatics in Medicine Unlocked, 43: 101406, https://doi.org/10.1016/j.imu.2023.101406.
• Chukwuma, I.F., Ezeorba, T.P.C, Nworah, F.N., Apeh, V.O., Khalid, M. and Sweilam, S.H. (2023). Bioassay-guided identification of potential Alzheimer’s disease therapeutic agents from kaempferol-enriched fraction of Aframomum melegueta seeds using in vitro and chemoinformatics approaches. Arabian Journal of Chemistry, 16: 105089. https://doi.org/10.1016/j.arabjc.2023.105089.
• Chukwuma, I.F., Uchendu, N.O., Asomadu, R.O., Ezeorba, W.F.C. and Ezeorba, T.P.C. (2023). African and holy basil - a review of ethnobotany, phytochemistry, and toxicity of their essential oil: Current trends and prospects for antimicrobial/antiparasitic pharmacology. Arabian Journal of Chemistry, 16: 104870.. https://doi.org/10.1016/j.arabjc.2023.104870.
• Onyesifea, C.O., Chukwuma, I.F., Okagua, I.U., Ndefo, J.C., Amujiri, N.A., Ogugua, V.N. (2023). Nephroprotective effects of Piper nigrum extracts against monosodium glutamate-induced renal toxicity in rats. Scientific African 19: e01453. https://doi.org/10.1016/j.sciaf.2022.e01453.
• Nworah, F.N., Uchendu, N.O., Chukwuma, I.F., Ossai, E.C., and Ezeako, E.C. (2023). Antioxidative and haematopoietic potential of Pelusios sinuatus (turtle) blood on myelosuppressed Wistar albino rats. Pakistan Journal of Zoology, 55(1):347-353, doi:https://dx.doi.org/10.17582/journal.pjz/20201114021133.
• Chukwuma, I.F., Apeh, V.O., Nworah, F.N., Nkwocha, C.C., Mba, S.E. and Ossai, E.C. (2023). Phytochemical profiling and antioxidative potential of phenolic-rich extract of Cola acuminata nuts. Biointerface Research in Applied Chemistry, 13(1):29-39. doi: 10.33263/briac131.029.
• Nworah, F., Chukwuma, I, Osuji, D. and Ezeako E. (2023). Assessment of the aqueous methanol extract and ethyl acetate fraction of Tapinanthus globiferus leaves and their effects on ulceration and leukocyte mobilization in Wistar albino rats. Letters in Applied Nanobioscience, 12 (3):79. https://doi.org/10.33263/lianbs123.079
• Chukwuma, I.F., Aniagboso, K.T., Atrogo, B.E., Ese, U.E., Ezeali, O., Ese, A.U., Onuorah, S.N., Onyishi, S.T., Titus, B.M. and Ugwu, E.I. (2022). Elucidation of the phytochemicals, safety profile, and preclinical anti-inflammatory activity of ethanol extract of Combretum paniculatum leaves. Tropical Journal of Natural Product Research, 6(12):2035-2040. http://www.doi.org/10.26538/tjnpr/v6i12.22.
• Chukwuma, I.F., Apeh, V.O., Nworah, F.N., Nwafor, F.I., Ezeanyika, L.U.S. and Ogugua, N. (2022). Protective effects of Brenania brieyi (de wild) E.M.A. petit root bark fractions against inflammatory-mediated hemolysis and dyslipidemia in rats. Istanbul Journal of Pharmacy, 52(3), 271-280. doi: 10.26650/istanbuljpharm.2022.1007696.
• Nworah, F.N., Chukwuma, I.F., Nwanelo, V.O., Osuji, D.O,, Onyeso, S.S., Iwuji, G.O., Ngwu, I.N., Odo, C.P., Okoroafor, C.C., Nkwocha,A.C. and Ezeako, E.C. (2022). Gastroprotective effect of aqueous Achatina achatina l. (snail) slime extract on indomethacin- and acidified ethanol-induced ulceration in wistar albino rats. Pakistan Veterinary Journal, 42(4): 571-575. http://dx.doi.org/10.29261/pakvetj/2022.071.
• Chukwuma, I.F., Nworah, F.N., Apeh, V.O., Omeje, K.O., Nweze, E.J., Asogwa, C.D. and Ezeorba T.P.C. (2022). Phytochemical characterization, functional nutrition, and anti-diabetic potentials of Leptadenia hastata (pers) decne leaves: in silico and in vitro studies. Bioinformatics and Biology Insights. 16:1-17. doi: 10.1177/11779322221115436.
• Johnson, T.O., Adegboyega, A.E., Ojo, O.A., Yusuf, A.J., Iwaloye, O., Ugwah-Oguejiofor, C.J., Asomadu, R.O., Chukwuma, I.F., Ejembi, S.A., Ugwuja, E.J., Alotaibi, S.S., Albogami, S.M., Batiha ge-s, Rajab, B.S., and Conte-junior, C.A. (2022) A computational approach to elucidate the interactions of chemicals from Artemisia annua targeted toward SARS-COV-2 main protease inhibition for COVID-19 treatment. Frontier in Medicine, 9:907583. doi: 10.3389/fmed.2022.907583.
• Nkwocha, C.C., Ogugofor, M., Chukwuma, I.F. and Njoku, O.U. (2022). Identification and characterization of phytochemicals and constituents in Desmodium velutinum stem using high-performance liquid chromatography (hplc). Pharmacological Research-Modern Chinese Medicine, 3,100090. https://doi.org/10.1016/j.prmcm.2022.100090.
• Chukwuma, I.F., Apeh, V.O., Nworah, F.N., Nkwocha, C.C., Emaimo, J., Ezeanyika, L.U.S. and Ogugua, V.N. (2022). Inhibition of phospholipase A2 and prostaglandin synthase activities as possible mechanistic insight into the anti-inflammatory activity of Brenania brieyi methanol and chloroform fractions. Thai Journal of Pharmaceutical Sciences, 46 (1): 75-84. http://www.tjps.pharm.chula.ac.th.
• Apeh, V.O., Asogwa, E., Chukwuma, I.F., Okonkwo, O.F., Nwora, F. and Uke, R. (2022). Chemical analysis and in silico anticancer and anti‑inflammatory potentials of bioactive compounds from Moringa oleifera seed oil. Advances in Traditional Medicine, 22 (1): 59-74. https://doi.org/10.1007/s13596-020-00521-y
• John, J.I., Uchendu, N.O., Chukwuma, I.F., Ogugofor, M.O., Ezeanyika, L.U.S. (2022). Chemotherapeutic evaluation of ethanol extract of Chromolaena odorata on biochemical aberrations associated with experimentally-induced benign prostatic hyperplasia in male rats. Biointerface Research in Applied Chemistry, 12 (6):8426-8440 https://doi.org/10.33263/briac126.84268440.
• Apeh, V.O., Njoku, O.U., Nwodo, F.O.C., Chukwuma, I.F. and Emmanuel, A.A..(2022). in silico drug-like properties prediction and in vivo antifungal potentials of Citrullus lanatus seed oil against Candida albicans, Arabian Journal of Chemistry,15(2):103578. https://doi.org/10.1016/j.arabjc.2021.103578.
• Apeh, V.O., Chukwuma, I.F., Nworah, F.N., Njoku, O.U..and Nwodo, F.O. (2021). Significance of crude and degummed Citrullus lanatus seed oil on inflammatory cytokines in experimental infection induced by candida albicans, Acta Pharmaceutica Sciencia, 59 (3): 363-383. doi: 10.23893/1307-2080.aps.05922
• Chukwuma, I.F., Apeh, V.O. and Nwodo, O.F.C. (2021). Mechanisms and potential therapeutic targets of hyperinflammatory responses in SARS-COV2. Acta Virologica, 65: 12 – 19. doi: 10.4149/av_2021_102.
• Chukwuma, I.F., Apeh, V.O. and Emaimo, J. (2020). Cross talk on SARS-COV-2 and human immunity. Nigeria Journal of Pharmaceutical Research, 16: 51-59. https://doi.org/10.4314/njpr.v16i2.7s.
• Chukwuma, I.F., Nkwocha, C.C., Ezeanyika, L.U.S., and Ogugua, V.N. (2020). Phytochemical investigation and in vitro antioxidant potency of root bark of Brenania brieyi fractions. Tropical Journal of Natural Product Research, 4(11):970-975. doi: 10.26538/tjnpr/v4i11.21
• Nkwocha, C.C., Chukwuma, I.F., and Umeakuana, C.D. (2019). Fatty acid profile of some selected vegetable consumed in Enugu State, Nigeria. American Journal of Food and Nutrition, 7 (4):130-135.
• Ekwueme, F.N., Nwodo, O.F.C., Eluka, P.E., Nkwocha, C., Ezugwu, A.L. and Odo, I.F. (2015). Evaluating the immunomodulatory potential of the aqueous leaf extract of Senna mimosoides in wistar albino rats. Journal of Pharmacy and Biological Sciences, 10(2):83-89.
• Odo, I.F., Ezeanyika, L.U.S., Ogugua, V.N., Joshua. P. E. and Okagu, I.U.. (2017). FTIR and GC-MS spectroscopic analysis of methanol and chloroform extracts of Brenania brieyi root bark. American Journal of Research Communication, 5(3): 44 -54.
• Odo, I.F., Ezeanyika, L.U.S. and Uchendu, N. (2015). The relationship among body composition and body mass index in a population of adolescents in Enugu State, Nigeria. International Journal of Current Microbiology and Applied Sciences, 4 (1): 884-897.
• Odo, I.F., Ezeanyika, L.U.S., Joshua, P.E., Uchendu, O.N., Ekwueme, N.K, Ezugwu, A.L. and Idoko, N.D. (2014). Prevalence and pattern of overweight and obesity in adolescents living in urban and rural settings of enugu state, nigeria. World Engineering and Applied Science Journal, 5(2):23-29.

Chukwuma, I.F., Okafor, K.C., Apeh, V.O., Nworah, F.N., Odo, C.P., Okafor, I.P., Anoh, K., Okoronkwo, O.C. (2024). Utilizing mechatronic agilent gas chromatography to validate therapeutic efficacy of Combretum paniculatum against oxidative stress and inflammation,
Heliyon, 10, (18): e36586, https://doi.org/10.1016/j.heliyon.2024.e36586.

Chukwuma, I.F., Atikpoh, C.E., Apeh, V.O., Nworah, F.N., Ezeanyika, L.U.S. (2024). Probing the Therapeutic Efficacy of Combretum paniculatum Extract and GC-FID-Identified Phytochemicals as Novel Agents for Diabetes Mellitus. Bioinform Biol Insights. 18: 1–15. doi: 10.1177/11779322241271537.